In Scarcity and Abundance
Similarly, the increase in ATP concentration upon glucose stimulation of pancreatic beta-cells triggers insulin secretion but might also contribute to the activation of PKA (85, 100).
Metabolic cycles and signals for insulin secretion
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Thus, regulatory or effectory processes would have to discriminate between a very high NADPH/NADP + ratio and a slightly higher ratio upon glucose stimulation . At the time of this writing, such a molecular target of NADPH with these biochemical features remains to be identified.
Useful Notes on Increased In Abundance Upon Glucose Stimulation
After glucose stimulation (8 mmol/l glucose , middle), most beta cells are metabolically activated given the synchronisation facilitated by functional Cx36 channels. As a result, the number of exocytotic events markedly increases, and a larger proportion of beta cells contribute to insulin secretion.
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Figure 1 from Stimulation of glucose transport by thyroid hormone in. It gives the article a little more context before the image collection begins.
Secretion of insulin peptides into the circulation upon glucose. It gives the article a little more context before the image collection begins.
Figure 2 from Stimulation of glucose transport by thyroid hormone in. It works as a short bridge between the article summary and the gallery section.
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