Diabetes and gut microbiome
The pathogenesis of the two most common subtypes of diabetes mellitus, type 1 (T1DM) and type 2 (T2DM), is substantially different, so each form is characterized by a different causation, etiology, pathophysiology, presentation, and treatment.
Type 2 diabetes (T2D), the most prevalent form, is a complex disease with numerous contributing factors, including genetics, epigenetics, diet, lifestyle, medication use, and socioeconomic factors. In addition, the gut microbiome has emerged as a significant potential contributing factor in T2D development and progression.
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5 ). The gut bacterial microbiome has been associated with the pathophysiology of multiple chronic diseases, one of which is Type 2 diabetes mellitus (T2DM) ( 6 - 8 ). Type 2 diabetes mellitus (T2DM) is characterized by chronic hyperglycemia due to decreased insulin secretion by pancreatic beta cells and increased insulin resistance.
The inhabitants of our intestines, collectively called the gut microbiome , comprise fungi, viruses, and bacterial strains. These microorganisms are involved in the fermentation of dietary compounds and the regulation of our adaptive and innate immune systems. Less known is the reciprocal interaction between the gut microbiota and type 2 diabetes mellitus (T2DM), as well as their role in ...
Changes to Gut Microbiome May Increase Type 2 Diabetes Risk
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Gut microbiome: A revolution in type II diabetes mellitus. This note connects the source idea with the visuals in a simple, reader-friendly way.
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