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GLP-1 receptor agonists represent the most significant advance in obesity medicine in a generation. This comprehensive guide covers the science, evidence, eligibility criteria, access options , realistic outcomes, and what to expect on treatment.

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The name behind the GLP-1 acronym is Glucagon-like peptide-1. This class of medications work by mimicking a hormone produced in your small intestine which slows digestion, helps you feel fuller for longer and triggers an insulin release, lowering blood sugar. 2 Once used exclusively to help manage type 2 diabetes, GLP-1s are now being prescribed for weight loss . Dual medications combining GLP ...

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What are GLP-1s ? GLP-1 receptor agonists work by targeting GLP-1 receptors: increasing insulin, decreasing glucagon and delaying gastric emptying. Originally developed for use in type 2 diabetes mellitus, GLP-1s are increasingly being licensed for weight-loss and other cardiometabolic applications. Some newer drugs combine GLP-1 receptor agonists with other metabolic targets or additional ...

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GLP-1 therapies (glucagon-like peptide-1 receptor agonists) are a class of medications that mimic the natural GLP-1 hormone, which helps regulate blood sugar and appetite. They were originally used for managing type 2 diabetes, but are now also approved for treating obesity and weight loss . Some GLP-1 drugs lower the risk of heart attack, stroke, and heart failure, and reduce the incidence of ...

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