Remdesivir targets the viral RNA polymerase, just likeFavipiravir, and is incorporated into the virus ' RNA. Unlike Favipiravir, which causes mutations in the viral RNA, however, Remdesivir insertion completely stops the formation of new RNA. Any new RNA means any virus new to it.
Hydroxychloroquine 's action is quite different from those two medications. Hydroxychloroquine and chloroquine are immunomodulatory drugs that eliminate body inflammation. Inflammation and excess cytokines are two significant causes of lung damage and death in patients with COVID-19.
What's more: Favipiravir and Remdesivir inhibit polymerase RNA in two ways. RNA is an abbreviation of ribonucleic acid as you know it. Both Favipiravir and Remdesivir are analogs of nucleoside, meaning they contain a nitrogen base and a cube of sugar.
And though Remdesivir competes in the viral RNA with the ATP, Favipiravir is a purine analog. And it competes with both the base A and G. What this means is that while Remdesivir replaces the ATP in the viral RNA, to change the virus so that it can no longer make copies of itself, Favipiravir attempts to achieve the same effect by attempting to take the place of A and G nitrogenic bases in the RNA.
ATP, or triphosphate from adenosine, is one of four organic compounds that make up an RNA chain. The remaining 3 are GTP, CTP, and UTP. A and G are called purines, while pyrimidines are called C, and U. Flu-virus studies have shown that Favipiravir (259793-96-9) causes changes in the virus ' RNA sequence from G to A and C to U.
Does Favipiravir experience any side effects? Is it safe for people with other conditions and pregnant women? Favipiravir in pregnant women is contraindicated as animal studies have shown that this drug can have adverse effects on the fetus. Those with a history of allergy to any of Favipiravir 's ingredients are not administered this drug.