Data from epidemiological studies suggest an increased risk of miscarriage and of cardiac malformation and gastroschisis after use of a prostaglandin synthesis inhibitor in early pregnancy. Key takeaways: Ibuprofen is not considered safe for pregnant women to use to relieve pain or fever. Studies show ibuprofen may increase the risk of miscarriage in the first trimester, the risk of pregnancy complications in the third trimester, and the risk of labor and postpartum complications. The use of ibuprofen during pregnancy presents important discussions regarding safety and efficacy. This section highlights the potential risks associated with ibuprofen use, answering key concerns regarding how it may impact both the mother and the developing fetus. Can ibuprofen affect pregnancy? Some evidence suggests that taking ibuprofen in the first month of pregnancy could increase the risk of , and the U.S. Food and Drug Administration (FDA) has found evidence that taking ibuprofen during the third trimester can affect the healthy development of your growing baby. Can I take ibuprofen If I'm 20 weeks pregnant? Don't take ibuprofen if you are 20 weeks or more pregnant as it can lead to poor kidney function in the fetus. It's not clear if it's safe to take ibuprofen before 20 weeks of pregnancy. It's safest to use Tylenol instead of ibuprofen for pain during pregnancy. When should you avoid taking ibuprofen during pregnancy? Experts recommend avoiding ibuprofen after 20 weeks. This recommendation comes from the Food and Drug Administration (FDA). Additionally, some research suggests a link between taking ibuprofen in pregnancy and problems with fetal development (commonly known as birth defects) even when taken before 20 weeks. Does ibuprofen affect fertility? Some studies suggest ibuprofen could affect male fertility (ability to get a woman pregnant), and others do not. Studies have not been done to see if ibuprofen could increase the chance of birth defects. In general, exposures that men have are unlikely to increase risks to a pregnancy. Research has established that ibuprofen can be risky after the midpoint of pregnancy, which is about 20 weeks. The FDA advises against using ibuprofen after this point in pregnancy...

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