As a hormone, melatonin is released by the pineal gland and is involved in sleepwake cycles. As a supplement and medication, it is often used for the short-term treatment of disrupted sleep patterns such as from jet lag or shift work, and is typically taken orally.
In most cases, you can treat melatonin overdoses with time and rest. Very few require hospitalization. Life-threatenting overdoses are rare, but overdoses can cause noticeable side effects, including difficulty breathing, seizures, or a loss of consciousness.
Melatonin Overdose (14 Effects of an Overdose) How much is too much?

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Melatonin is becoming a popular supplement for those struggling with sleep. But there has recently been a big spike in the number of overdoses. What harm can too much of it do? Hands up those who use their smartphone in bed.
Check out our guide on the Best Melatonin Supplements. While melatonin may cause unwanted side effects, the question as to whether or not you can experience a lethal overdose from it appears to be generally no.

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A 16-year-old male overdosed on 900mg of melatonin and benzodiazepines, obtained online without prescription. The case underscores rising melatonin abuse due to easy access. Despite low toxicity potential, side effects and fatalities are concerning.
Melatonin side effects include drowsiness, as expected, and dizziness, but otherwise are about the same as placebo pills (sugar pills). People with seizure disorders should not take melatonin, as there are some reports of seizures occurring in people who took it.

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How to Treat Melatonin Overdose? Side effects do exist with melatonin overdose, but serious side effects are rare. Treatment of overdose depends on the severity of the symptoms. An individual taking melatonin should consult a doctor if one experiences: High blood pressure.
Case report on melatonin overdose: Cause and concern.