A Novel Orally Active Inverse Agonist of Estrogen
Estrogen -related receptor gamma (ERRγ), one of three members of the ERR family, is an inducible transcription factor. ERRγ has dual functions in different tissues.
Exploring the impact of estrogen
ERRγ is a key regulator of metabolic gene expression. ERRγ is involved in crosstalk with the endocrine pathway and other metabolic pathways. Dysregulation of ERRγ contributes to various diseases and metabolic conditions. Targeting ERRγ is a potential approach for treating metabolic diseases.
However, the mechanisms regulating hepatic DAGL gene expression and 2-AG production are largely unknown. In this study, we show that CB1R-induced estrogen -related receptor γ (ERRγ) controls hepatic DAGL gene expression and 2-AG levels.
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Useful Notes on Estrogen Receptor Gamma Agonist
Direct regulators of nuclear-encoded mitochondrial genes are members of the estrogen -related receptor (ERR) family, encoded by Esrra, Esrrb and Esrrg. Members of this family show sequence...
DY131 is a pharmacological agonist of the orphan receptor estrogen -related receptor (ERR) γ which plays a crucial role in regulating energy generation, oxidative metabolism, cell apoptosis, inflammatory responses, etc.
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Estrogen and Related Receptors | ER | ERR | Tocris Bioscience. It gives the article a little more context before the image collection begins.
Inverse Agonist of Estrogen-Related Receptor γ Enhances Sodium Iodide. This note connects the source idea with the visuals in a simple, reader-friendly way.
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