Antiinflammatory actions of glucagon
In the liver, the researchers also found GLP-1 receptors in immune cells called T cells, which could contribute some anti-inflammatory benefits , but their role couldn't be confirmed in the study.
Key Details About Glp-1 Suppresses Inflammation Immune Benefits
GLP-1 is involved in several pathophysiological processes, including appetite regulation, cardiovascular function, and inflammation . Inflammation is a complex biological response mediated by both innate and adaptive immune mechanisms, initially aimed at restoring tissue homeostasis following internal or external insults.
While GLP -1RAs ability to lower plasma glucose and to induce weight loss has allowed them to be approved for the treatment of diabetes and obesity, consistent evidences from in vitro studies and preclinical models suggested that GLP -1RAs have anti-inflammatory properties and that may modulate the immune -system.
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