Hookworm infection associates with a vaginal Type 1Type 2 immune ...
A pronounced mixed Type 1/Type 2 immune response was detected in the vaginal fluids of women with hookworm infection and this immune signature was a notable feature in hookworm -HPV co-infected women. Moreover, hookworm infection is positively associated with increased risk and load of HPV infection .
Helminth infection -driven changes to immunity in the female reproductive tract (FRT) is an immune axis that is currently understudied but can have major implications for the control of FRT infections . Here we address how human hookworm infection associates with vaginal immune profile and risk of Human papillomavirus (HPV) infection .
Hookworm infection associates with a vaginal Type 1Type 2 immune ...
A pronounced mixed Type 1/Type 2 immune response was detected in the vaginal fluids of women with hookworm infection and this immune signature was a notable feature in hookworm -HPV co-infected women.
Here we address how human hookworm infection associates with vaginal immune profile and risk of Human papillomavirus (HPV) infection . Stool, blood, cervical swabs and vaginal flushes were collected from women from the Central region of Togo to screen for hookworms ( and high carcinogenic risk HPV types , Kato Katz and PCR, respectively.
DataSheet1Hookworm infection associates with a vaginal Type 1Type 2 ...
A pronounced mixed Type 1/Type 2 immune response was detected in the vaginal fluids of women with hookworm infection and this immune signature was a notable feature in hookworm -HPV co-infected women. Moreover, hookworm infection is positively associated with increased risk and load of HPV infection .
Millicent A Omondi's 3 research works with 21 citations and 606 reads, including: Hookworm infection associates with a vaginal Type 1/Type 2 immune signature and increased HPV load
Hookworm infection associates with a vaginal Type 1Type 2 immune ...
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Influence of helminth infection on vaginal immunity
In summary, this thesis demonstrates that helminth infection induces Type 2 associated immune changes in the female reproductive tract in humans and alters B and T cell populations in lymph nodes draining the female reproductive tract of mice.
A comprehensive understanding of the molecular interactions between the parasite and host is vital for unraveling the complexities of infection dynamics. This study aimed to identify the immune system components responsible for host specificity in hookworms by infecting immunodeficient mouse models.