Fibroblast Multipotent at Bill Kemp blog

Fibroblast Multipotent. Cardiac fibroblasts (cfs) play critical roles in heart development, homeostasis, and disease. Here, we demonstrate the generation of multipotential cells from adult human dermal fibroblast cells by incorporating lab. In this study, we present a novel role for sall4/gata4 interaction in transitioning cardiac fibroblasts into a multipotent primitive. These results suggest that 7f reprogram mefs more efficiently than oct4, sox2, klf4, and myc and thus may represent an alternative path to pluripotency. The limited availability of human cfs from native heart impedes investigations of cf. We then show that 7f can also reprogram tail tip fibroblasts (ttfs) to ipscs (figures 2c and 2d). In this study, we describe a technically straightforward approach to create induced multipotent cells from somatic cells.

Figure 1 from Open Access Research Article Differentiation of Human
from www.semanticscholar.org

In this study, we describe a technically straightforward approach to create induced multipotent cells from somatic cells. Cardiac fibroblasts (cfs) play critical roles in heart development, homeostasis, and disease. The limited availability of human cfs from native heart impedes investigations of cf. Here, we demonstrate the generation of multipotential cells from adult human dermal fibroblast cells by incorporating lab. These results suggest that 7f reprogram mefs more efficiently than oct4, sox2, klf4, and myc and thus may represent an alternative path to pluripotency. We then show that 7f can also reprogram tail tip fibroblasts (ttfs) to ipscs (figures 2c and 2d). In this study, we present a novel role for sall4/gata4 interaction in transitioning cardiac fibroblasts into a multipotent primitive.

Figure 1 from Open Access Research Article Differentiation of Human

Fibroblast Multipotent In this study, we present a novel role for sall4/gata4 interaction in transitioning cardiac fibroblasts into a multipotent primitive. We then show that 7f can also reprogram tail tip fibroblasts (ttfs) to ipscs (figures 2c and 2d). Cardiac fibroblasts (cfs) play critical roles in heart development, homeostasis, and disease. In this study, we describe a technically straightforward approach to create induced multipotent cells from somatic cells. In this study, we present a novel role for sall4/gata4 interaction in transitioning cardiac fibroblasts into a multipotent primitive. Here, we demonstrate the generation of multipotential cells from adult human dermal fibroblast cells by incorporating lab. These results suggest that 7f reprogram mefs more efficiently than oct4, sox2, klf4, and myc and thus may represent an alternative path to pluripotency. The limited availability of human cfs from native heart impedes investigations of cf.

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