cdc2k dephosphorylation
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion Reaction3 CP STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Reaction3 C2 STOICHIOMETRY
xref: GO:0006470
xref: http://identifiers.org/ec-code/3.1.3.16
right: C2
left: CP

cdc2k phosphorylation
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion Reaction2 CP STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Reaction2 C2 STOICHIOMETRY
xref: http://identifiers.org/ec-code/2.7.11.1
xref: GO:0006468
right: CP
left: C2

deactivation of cdc2 kinase
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion Reaction5 pM STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Reaction5 M STOICHIOMETRY
xref: REACT 6327
xref: http://identifiers.org/ec-code/2.7.10.2
xref: GO:0045736
xref: GO:0006468
xref: REACT 3178
right: pM
left: M

cyclin cdc2k-p association
type: ComplexAssembly
participant stoichiometry: RIGHT 0 conversion Reaction4 pM STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Reaction4 CP STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion Reaction4 Y STOICHIOMETRY
xref: REACT 6308
xref: REACT 6216
right: pM
spontaneous: true
left: CP
left: Y
conversion direction: LEFT_TO_RIGHT

default degradation of cyclin
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion Reaction7 EmptySet STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Reaction7 Y STOICHIOMETRY
xref: GO:0008054
right: EmptySet
left: Y

cyclin biosynthesis
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion Reaction6 Y STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Reaction6 EmptySet STOICHIOMETRY
xref: GO:0006412
right: Y
left: EmptySet

P04551
type: UnificationXref
id: P04551
db: UniProt Knowledgebase

activation of cdc2 kinase
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion Reaction9 M STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Reaction9 pM STOICHIOMETRY
xref: GO:0006470
xref: REACT 6175
xref: REACT 6294
xref: http://identifiers.org/ec-code/3.1.3.16
xref: GO:0045737
xref: REACT 6257
right: M
left: pM

EmptySet
type: PhysicalEntity

YP
type: PhysicalEntity
member physical entity: p-cyclin
cellular location: cell

cdc2 kinase triggered degration of cyclin
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion Reaction8 EmptySet STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Reaction8 YP STOICHIOMETRY
xref: GO:0008054
right: EmptySet
left: YP

pM
type: PhysicalEntity
member physical entity: p-cyclin_cdc2-p
cellular location: cell

GO:0006412
type: UnificationXref
id: GO:0006412
db: Gene Ontology

Y
type: PhysicalEntity
member physical entity: cyclin
cellular location: cell

http://identifiers.org/pubmed/1831270
type: PublicationXref
id: 1831270
db: PubMed

GO:0000278
type: UnificationXref
id: GO:0000278
db: Gene Ontology

GO:0000079
type: UnificationXref
id: GO:0000079
db: Gene Ontology

LEFT 0 conversion Reaction1 M STOICHIOMETRY
type: Stoichiometry
physical entity: M
stoichiometric coefficient: 1.0

RIGHT 0 conversion Reaction6 Y STOICHIOMETRY
type: Stoichiometry
physical entity: Y
stoichiometric coefficient: 1.0

pM
type: PhysicalEntity
member physical entity: p-cyclin_cdc2-p
cellular location: cell

p-cyclin
type: Protein
xref: IPR006670

RIGHT 1 conversion Reaction1 YP STOICHIOMETRY
type: Stoichiometry
physical entity: YP
stoichiometric coefficient: 1.0

M
type: PhysicalEntity
member physical entity: p-cyclin_cdc2
cellular location: cell

MODEL6614644188
type: UnificationXref
id: MODEL6614644188
db: BioModels Database

sce04111
type: UnificationXref
id: sce04111
db: KEGG Pathway

total_cyclin
type: Protein
xref: IPR006670

http://identifiers.org/ec-code/2.7.10.2
type: UnificationXref
id: 2.7.10.2
db: Enzyme Nomenclature

C2
type: PhysicalEntity
member physical entity: cdc2k
cellular location: cell

YP
type: PhysicalEntity
member physical entity: p-cyclin
cellular location: cell

CP
type: PhysicalEntity
member physical entity: cdc2k-P
cellular location: cell

REACT 6175
type: UnificationXref
id: REACT_6175
db: Reactome

RIGHT 0 conversion Reaction5 pM STOICHIOMETRY
type: Stoichiometry
physical entity: pM
stoichiometric coefficient: 1.0

REACT 6294
type: UnificationXref
id: REACT_6294
db: Reactome

CP
type: PhysicalEntity
member physical entity: cdc2k-P
cellular location: cell

LEFT 0 conversion Reaction6 EmptySet STOICHIOMETRY
type: Stoichiometry
physical entity: EmptySet
stoichiometric coefficient: 1.0

C2
type: PhysicalEntity
member physical entity: cdc2k
cellular location: cell

EmptySet
type: PhysicalEntity
member physical entity: EmptySet
cellular location: cell

GO:0006468
type: UnificationXref
id: GO:0006468
db: Gene Ontology

GO:0006470
type: UnificationXref
id: GO:0006470
db: Gene Ontology

REACT 152
type: UnificationXref
id: REACT_152
db: Reactome

REACT 6327
type: UnificationXref
id: REACT_6327
db: Reactome

M
type: PhysicalEntity
member physical entity: p-cyclin_cdc2
cellular location: cell

GO:0008054
type: UnificationXref
id: GO:0008054
db: Gene Ontology

M
type: PhysicalEntity
member physical entity: p-cyclin_cdc2
cellular location: cell

http://identifiers.org/taxonomy/33154
type: UnificationXref
id: 33154
db: Taxonomy

LEFT 0 conversion Reaction2 C2 STOICHIOMETRY
type: Stoichiometry
physical entity: C2
stoichiometric coefficient: 1.0

cyclin_cdc2k dissociation
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion Reaction1 M STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion Reaction1 YP STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Reaction1 C2 STOICHIOMETRY
xref: REACT 6308
xref: GO:0000079
right: YP
right: C2
spontaneous: true
left: M
conversion direction: RIGHT_TO_LEFT

REACT 3178
type: UnificationXref
id: REACT_3178
db: Reactome

LEFT 0 conversion Reaction5 M STOICHIOMETRY
type: Stoichiometry
physical entity: M
stoichiometric coefficient: 1.0

Y
type: PhysicalEntity
member physical entity: cyclin
cellular location: cell

LEFT 0 conversion Reaction3 CP STOICHIOMETRY
type: Stoichiometry
physical entity: CP
stoichiometric coefficient: 1.0

CP
type: PhysicalEntity
member physical entity: cdc2k-P
cellular location: cell

IPR006670
type: UnificationXref
id: IPR006670
db: InterPro

BIOMD0000000005
type: Pathway
pathway component: cdc2k dephosphorylation
pathway component: cdc2k phosphorylation
pathway component: deactivation of cdc2 kinase
pathway component: cyclin cdc2k-p association
pathway component: default degradation of cyclin
pathway component: cyclin biosynthesis
pathway component: activation of cdc2 kinase
pathway component: cdc2 kinase triggered degration of cyclin
pathway component: cyclin_cdc2k dissociation
xref: REACT 152
xref: MODEL6614644188
xref: sce04111
xref: http://identifiers.org/pubmed/1831270
xref: GO:0000278
xref: BIOMD0000000005
organism: biosource 1
comment: This BioPAX Level3 file was automatically generated on 23-Jun-2017 by SBML2BioPAX-3.1, BioModels.net, EMBL-EBI.
comment: The original model, 'BIOMD0000000005', was published in BioModels Database (http://www.ebi.ac.uk/biomodels/).
data source: BioModels Database

cell
type: CellularLocationVocabulary
xref: GO:0005623

GO:0005623
type: UnificationXref
id: GO:0005623
db: Gene Ontology

p-cyclin_cdc2
type: Complex
xref: P04551
xref: IPR006670

RIGHT 0 conversion Reaction3 C2 STOICHIOMETRY
type: Stoichiometry
physical entity: C2
stoichiometric coefficient: 1.0

cdc2k
type: Protein
xref: P04551

EmptySet
type: PhysicalEntity
member physical entity: EmptySet
cellular location: cell

RIGHT 0 conversion Reaction9 M STOICHIOMETRY
type: Stoichiometry
physical entity: M
stoichiometric coefficient: 1.0

RIGHT 0 conversion Reaction8 EmptySet STOICHIOMETRY
type: Stoichiometry
physical entity: EmptySet
stoichiometric coefficient: 1.0

cyclin
type: Protein
xref: IPR006670

LEFT 1 conversion Reaction4 Y STOICHIOMETRY
type: Stoichiometry
physical entity: Y
stoichiometric coefficient: 1.0

http://identifiers.org/ec-code/2.7.11.1
type: UnificationXref
id: 2.7.11.1
db: Enzyme Nomenclature

REACT 6216
type: UnificationXref
id: REACT_6216
db: Reactome

p-cyclin_cdc2-p
type: Complex
xref: P04551
xref: IPR006670

BIOMD0000000005
type: UnificationXref
id: BIOMD0000000005
db: BioModels Database

REACT 6257
type: UnificationXref
id: REACT_6257
db: Reactome

BioModels Database
type: Provenance
xref: BIOMD0000000005

LEFT 0 conversion Reaction7 Y STOICHIOMETRY
type: Stoichiometry
physical entity: Y
stoichiometric coefficient: 1.0

RIGHT 0 conversion Reaction2 CP STOICHIOMETRY
type: Stoichiometry
physical entity: CP
stoichiometric coefficient: 1.0

RIGHT 0 conversion Reaction1 C2 STOICHIOMETRY
type: Stoichiometry
physical entity: C2
stoichiometric coefficient: 1.0

LEFT 0 conversion Reaction9 pM STOICHIOMETRY
type: Stoichiometry
physical entity: pM
stoichiometric coefficient: 1.0

C2
type: PhysicalEntity
member physical entity: cdc2k
cellular location: cell

Y
type: PhysicalEntity
member physical entity: cyclin
cellular location: cell

cdc2k-P
type: Protein
xref: P04551

GO:0045737
type: UnificationXref
id: GO:0045737
db: Gene Ontology

GO:0045736
type: UnificationXref
id: GO:0045736
db: Gene Ontology

LEFT 0 conversion Reaction8 YP STOICHIOMETRY
type: Stoichiometry
physical entity: YP
stoichiometric coefficient: 1.0

BioModels Database
type: Provenance
xref: MODEL6614644188

REACT 6308
type: UnificationXref
id: REACT_6308
db: Reactome

total_cdc2
type: Protein
xref: P04551

RIGHT 0 conversion Reaction7 EmptySet STOICHIOMETRY
type: Stoichiometry
physical entity: EmptySet
stoichiometric coefficient: 1.0

http://identifiers.org/ec-code/3.1.3.16
type: UnificationXref
id: 3.1.3.16
db: Enzyme Nomenclature

RIGHT 0 conversion Reaction4 pM STOICHIOMETRY
type: Stoichiometry
physical entity: pM
stoichiometric coefficient: 1.0

LEFT 0 conversion Reaction4 CP STOICHIOMETRY
type: Stoichiometry
physical entity: CP
stoichiometric coefficient: 1.0

pM
type: PhysicalEntity
member physical entity: p-cyclin_cdc2-p
cellular location: cell

EmptySet
type: PhysicalEntity
member physical entity: EmptySet
cellular location: cell