APC_Cdc20
type: PhysicalEntity
member physical entity: APC:Cdc20
cellular location: Cytoplasm

OMad2
type: PhysicalEntity
member physical entity: O-Mad2
cellular location: Cytoplasm

Cdc20_CMad2
type: PhysicalEntity
member physical entity: Cdc20:C-Mad2
cellular location: Cytoplasm

MODEL6655578762
type: Pathway
pathway component: R7b
pathway component: R1
pathway component: R2
pathway component: R3
pathway component: R4
pathway component: R5
pathway component: R6
pathway component: R7
pathway component: R8
xref: hsa04110
xref: http://identifiers.org/pubmed/15694304
xref: BIOMD0000000187
xref: GO:0007094
xref: http://identifiers.org/pubmed/18253502
xref: REACT 2137.2
xref: MODEL6655578762
organism: biosource 1
comment: This BioPAX Level3 file was automatically generated on 23-Jun-2017 by SBML2BioPAX-3.1, BioModels.net, EMBL-EBI.
comment: The original model, 'MODEL6655578762', was published in BioModels Database (http://www.ebi.ac.uk/biomodels/).
data source: BioModels Database

RIGHT 0 conversion R4 MCC STOICHIOMETRY
type: Stoichiometry
physical entity: MCC
stoichiometric coefficient: 1.0

OMad2
type: PhysicalEntity
member physical entity: O-Mad2
cellular location: Cytoplasm

MCC_APC
type: PhysicalEntity
member physical entity: MCC:APC
cellular location: Cytoplasm

GO:0033597
type: UnificationXref
id: GO:0033597
db: Gene Ontology

RIGHT 0 conversion R1 Mad1 CMad2 OMad2 STOICHIOMETRY
type: Stoichiometry
physical entity: Mad1_CMad2_OMad2
stoichiometric coefficient: 1.0

Bub3_BubR1
type: PhysicalEntity
member physical entity: Bub3:BubR1
cellular location: Cytoplasm

Mad1_CMad2_OMad2
type: PhysicalEntity
member physical entity: Mad1:C-Mad2:O-Mad2*
cellular location: Cytoplasm

Cdc20
type: PhysicalEntity
member physical entity: Cdc20
cellular location: Cytoplasm

MODEL6655578762
type: UnificationXref
id: MODEL6655578762
db: BioModels Database

Cdc20
type: Protein
xref: Q12834

RIGHT 1 conversion R3 OMad2 STOICHIOMETRY
type: Stoichiometry
physical entity: OMad2
stoichiometric coefficient: 1.0

GO:0005737
type: UnificationXref
id: GO:0005737
db: Gene Ontology

APC
type: PhysicalEntity
member physical entity: APC
cellular location: Cytoplasm

RIGHT 1 conversion R2 Cdc20 CMad2 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdc20_CMad2
stoichiometric coefficient: 1.0

O43684
type: UnificationXref
id: O43684
db: UniProt Knowledgebase

R7b
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion R7b MCC APC STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R7b OMad2 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R7b Bub3 BubR1 STOICHIOMETRY
participant stoichiometry: RIGHT 2 conversion R7b APC Cdc20 STOICHIOMETRY
xref: GO:0007092
xref: GO:0043624
right: APC_Cdc20
right: Bub3_BubR1
right: OMad2
spontaneous: true
left: MCC_APC
conversion direction: LEFT_TO_RIGHT

LEFT 1 conversion R4 Bub3 BubR1 STOICHIOMETRY
type: Stoichiometry
physical entity: Bub3_BubR1
stoichiometric coefficient: 1.0

LEFT 0 conversion R3 Cdc20 CMad2 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdc20_CMad2
stoichiometric coefficient: 1.0

REACT 2137.2
type: UnificationXref
id: REACT_2137.2
db: Reactome

LEFT 1 conversion R8 Cdc20 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdc20
stoichiometric coefficient: 1.0

Q9UJX5
type: UnificationXref
id: Q9UJX5
db: UniProt Knowledgebase

Q9UJX4
type: UnificationXref
id: Q9UJX4
db: UniProt Knowledgebase

P30260
type: UnificationXref
id: P30260
db: UniProt Knowledgebase

Q9UJX3
type: UnificationXref
id: Q9UJX3
db: UniProt Knowledgebase

Bub3:BubR1:Cdc20
type: Complex
xref: Q12834
xref: Q60566
xref: O43684

Q9UJX2
type: UnificationXref
id: Q9UJX2
db: UniProt Knowledgebase

Q9Y6D9
type: UnificationXref
id: Q9Y6D9
db: UniProt Knowledgebase

Q9UJX6
type: UnificationXref
id: Q9UJX6
db: UniProt Knowledgebase

Bub3:BubR1
type: Complex
xref: Q60566
xref: O43684

GO:0032092
type: UnificationXref
id: GO:0032092
db: Gene Ontology

APC:Cdc20
type: Complex
xref: Q9UJX5
xref: Q9UJX4
xref: P30260
xref: Q9UJX3
xref: Q9UJX2
xref: Q13042
xref: Q9UJX6
xref: Q9UM13
xref: Q9NYG5
xref: Q9H1A4
xref: Q12834
xref: Q9BS18
xref: Q8NHZ8

GO:0043623
type: UnificationXref
id: GO:0043623
db: Gene Ontology

GO:0043624
type: UnificationXref
id: GO:0043624
db: Gene Ontology

Bub3_BubR1_Cdc20
type: PhysicalEntity
member physical entity: Bub3:BubR1:Cdc20
cellular location: Cytoplasm

Q9BS18
type: UnificationXref
id: Q9BS18
db: UniProt Knowledgebase

MCC:APC
type: Complex
xref: Q9UJX5
xref: Q9UJX4
xref: P30260
xref: Q9UJX3
xref: Q9UJX2
xref: Q13042
xref: Q9UJX6
xref: Q9UM13
xref: Q13257
xref: Q9NYG5
xref: O43684
xref: Q9H1A4
xref: Q12834
xref: Q9BS18
xref: GO:0033597
xref: GO:0005680
xref: Q8NHZ8
xref: Q60566

OMad2
type: PhysicalEntity
member physical entity: O-Mad2
cellular location: Cytoplasm

Mad1_CMad2
type: PhysicalEntity
member physical entity: Mad1:C-Mad2
cellular location: Cytoplasm

LEFT 1 conversion R1 OMad2 STOICHIOMETRY
type: Stoichiometry
physical entity: OMad2
stoichiometric coefficient: 1.0

Bub3_BubR1
type: PhysicalEntity
member physical entity: Bub3:BubR1
cellular location: Cytoplasm

http://identifiers.org/pubmed/15694304
type: PublicationXref
id: 15694304
db: PubMed

GO:0043234
type: UnificationXref
id: GO:0043234
db: Gene Ontology

Cdc20
type: PhysicalEntity
member physical entity: Cdc20
cellular location: Cytoplasm

MCC
type: Complex
xref: Q12834
xref: GO:0033597
xref: Q13257
xref: Q60566
xref: O43684

RIGHT 0 conversion R5 Bub3 BubR1 Cdc20 STOICHIOMETRY
type: Stoichiometry
physical entity: Bub3_BubR1_Cdc20
stoichiometric coefficient: 1.0

RIGHT 0 conversion R7b OMad2 STOICHIOMETRY
type: Stoichiometry
physical entity: OMad2
stoichiometric coefficient: 1.0

Cdc20
type: PhysicalEntity
member physical entity: Cdc20
cellular location: Cytoplasm

GO:0005680
type: UnificationXref
id: GO:0005680
db: Gene Ontology

LEFT 1 conversion R7 APC STOICHIOMETRY
type: Stoichiometry
physical entity: APC
stoichiometric coefficient: 1.0

APC_Cdc20
type: PhysicalEntity
member physical entity: APC:Cdc20
cellular location: Cytoplasm

LEFT 0 conversion R6 OMad2 STOICHIOMETRY
type: Stoichiometry
physical entity: OMad2
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/18253502
type: PublicationXref
id: 18253502
db: PubMed

Cytoplasm
type: CellularLocationVocabulary
xref: GO:0005737

RIGHT 2 conversion R7b APC Cdc20 STOICHIOMETRY
type: Stoichiometry
physical entity: APC_Cdc20
stoichiometric coefficient: 1.0

BIOMD0000000187
type: UnificationXref
id: BIOMD0000000187
db: BioModels Database

GO:0043241
type: UnificationXref
id: GO:0043241
db: Gene Ontology

Bub3_BubR1
type: PhysicalEntity
member physical entity: Bub3:BubR1
cellular location: Cytoplasm

LEFT 0 conversion R1 Mad1 CMad2 STOICHIOMETRY
type: Stoichiometry
physical entity: Mad1_CMad2
stoichiometric coefficient: 1.0

Mad1_CMad2
type: PhysicalEntity
member physical entity: Mad1:C-Mad2
cellular location: Cytoplasm

RIGHT 0 conversion R3 Cdc20 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdc20
stoichiometric coefficient: 1.0

MCC
type: PhysicalEntity
member physical entity: MCC
cellular location: Cytoplasm

Mad1_CMad2_OMad2
type: PhysicalEntity
member physical entity: Mad1:C-Mad2:O-Mad2*
cellular location: Cytoplasm

LEFT 0 conversion R4 Cdc20 CMad2 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdc20_CMad2
stoichiometric coefficient: 1.0

Mad1:C-Mad2:O-Mad2*
type: Complex
xref: Q9Y6D9
xref: Q13257
xref: GO:0043234

http://identifiers.org/taxonomy/9606
type: UnificationXref
id: 9606
db: Taxonomy

GO:0006461
type: UnificationXref
id: GO:0006461
db: Gene Ontology

Cdc20:C-Mad2
type: Complex
xref: Q12834
xref: Q13257

GO:0051436
type: UnificationXref
id: GO:0051436
db: Gene Ontology

MCC_APC
type: PhysicalEntity
member physical entity: MCC:APC
cellular location: Cytoplasm

LEFT 1 conversion R2 Cdc20 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdc20
stoichiometric coefficient: 1.0

RIGHT 0 conversion R2 Mad1 CMad2 STOICHIOMETRY
type: Stoichiometry
physical entity: Mad1_CMad2
stoichiometric coefficient: 1.0

Q13042
type: UnificationXref
id: Q13042
db: UniProt Knowledgebase

LEFT 0 conversion R2 Mad1 CMad2 OMad2 STOICHIOMETRY
type: Stoichiometry
physical entity: Mad1_CMad2_OMad2
stoichiometric coefficient: 1.0

O-Mad2
type: Protein
xref: Q13257

Cdc20_CMad2
type: PhysicalEntity
member physical entity: Cdc20:C-Mad2
cellular location: Cytoplasm

LEFT 0 conversion R5 Bub3 BubR1 STOICHIOMETRY
type: Stoichiometry
physical entity: Bub3_BubR1
stoichiometric coefficient: 1.0

RIGHT 1 conversion R7b Bub3 BubR1 STOICHIOMETRY
type: Stoichiometry
physical entity: Bub3_BubR1
stoichiometric coefficient: 1.0

Cdc20
type: PhysicalEntity
member physical entity: Cdc20
cellular location: Cytoplasm

LEFT 1 conversion R6 Cdc20 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdc20
stoichiometric coefficient: 1.0

MCC
type: PhysicalEntity
member physical entity: MCC
cellular location: Cytoplasm

Cdc20_CMad2
type: PhysicalEntity
member physical entity: Cdc20:C-Mad2
cellular location: Cytoplasm

Q9UM13
type: UnificationXref
id: Q9UM13
db: UniProt Knowledgebase

Q13257
type: UnificationXref
id: Q13257
db: UniProt Knowledgebase

Q9H1A4
type: UnificationXref
id: Q9H1A4
db: UniProt Knowledgebase

LEFT 0 conversion R7b MCC APC STOICHIOMETRY
type: Stoichiometry
physical entity: MCC_APC
stoichiometric coefficient: 1.0

Q12834
type: UnificationXref
id: Q12834
db: UniProt Knowledgebase

GO:0007094
type: UnificationXref
id: GO:0007094
db: Gene Ontology

REACT 36.2
type: UnificationXref
id: REACT_36.2
db: Reactome

GO:0007092
type: UnificationXref
id: GO:0007092
db: Gene Ontology

Cdc20_CMad2
type: PhysicalEntity
member physical entity: Cdc20:C-Mad2
cellular location: Cytoplasm

BioModels Database
type: Provenance
xref: BIOMD0000000187

hsa04110
type: UnificationXref
id: hsa04110
db: KEGG Pathway

LEFT 0 conversion R8 APC STOICHIOMETRY
type: Stoichiometry
physical entity: APC
stoichiometric coefficient: 1.0

Cdc20
type: PhysicalEntity
member physical entity: Cdc20
cellular location: Cytoplasm

R1
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R1 Mad1 CMad2 OMad2 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R1 Mad1 CMad2 STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R1 OMad2 STOICHIOMETRY
xref: GO:0043241
xref: GO:0006461
xref: GO:0032092
right: Mad1_CMad2_OMad2
left: OMad2
left: Mad1_CMad2

R2
type: ComplexAssembly
participant stoichiometry: LEFT 1 conversion R2 Cdc20 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R2 Mad1 CMad2 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R2 Cdc20 CMad2 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R2 Mad1 CMad2 OMad2 STOICHIOMETRY
xref: GO:0006461
xref: GO:0032092
right: Cdc20_CMad2
right: Mad1_CMad2
spontaneous: true
left: Cdc20
left: Mad1_CMad2_OMad2
conversion direction: LEFT_TO_RIGHT

Q9NYG5
type: UnificationXref
id: Q9NYG5
db: UniProt Knowledgebase

R3
type: ComplexAssembly
participant stoichiometry: RIGHT 0 conversion R3 Cdc20 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R3 Cdc20 CMad2 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R3 OMad2 STOICHIOMETRY
xref: GO:0043241
right: Cdc20
right: OMad2
spontaneous: true
left: Cdc20_CMad2
conversion direction: RIGHT_TO_LEFT

R4
type: ComplexAssembly
participant stoichiometry: LEFT 1 conversion R4 Bub3 BubR1 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R4 MCC STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R4 Cdc20 CMad2 STOICHIOMETRY
xref: GO:0043241
xref: GO:0006461
xref: REACT 36.2
right: MCC
spontaneous: true
left: Bub3_BubR1
left: Cdc20_CMad2
conversion direction: RIGHT_TO_LEFT

R5
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R5 Bub3 BubR1 Cdc20 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R5 Bub3 BubR1 STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R5 Cdc20 STOICHIOMETRY
xref: GO:0043241
xref: GO:0006461
right: Bub3_BubR1_Cdc20
left: Cdc20
left: Bub3_BubR1

R6
type: ComplexAssembly
participant stoichiometry: LEFT 1 conversion R6 Cdc20 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R6 OMad2 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R6 Cdc20 CMad2 STOICHIOMETRY
xref: GO:0006461
right: Cdc20_CMad2
spontaneous: true
left: Cdc20
left: OMad2
conversion direction: LEFT_TO_RIGHT

LEFT 1 conversion R5 Cdc20 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdc20
stoichiometric coefficient: 1.0

RIGHT 0 conversion R7 MCC APC STOICHIOMETRY
type: Stoichiometry
physical entity: MCC_APC
stoichiometric coefficient: 1.0

R7
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion R7 MCC STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R7 APC STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R7 MCC APC STOICHIOMETRY
xref: GO:0051436
xref: GO:0043623
right: MCC_APC
spontaneous: true
left: APC
left: MCC
conversion direction: RIGHT_TO_LEFT

BioModels Database
type: Provenance
xref: MODEL6655578762

R8
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R8 APC STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R8 Cdc20 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R8 APC Cdc20 STOICHIOMETRY
xref: GO:0007092
xref: GO:0043623
right: APC_Cdc20
left: APC
left: Cdc20

LEFT 0 conversion R7 MCC STOICHIOMETRY
type: Stoichiometry
physical entity: MCC
stoichiometric coefficient: 1.0

OMad2
type: PhysicalEntity
member physical entity: O-Mad2
cellular location: Cytoplasm

APC
type: Complex
xref: Q9UJX5
xref: Q9UJX4
xref: P30260
xref: Q9UJX3
xref: Q9UJX2
xref: Q13042
xref: Q9UJX6
xref: Q9UM13
xref: Q9NYG5
xref: Q9H1A4
xref: Q9BS18
xref: GO:0005680
xref: Q8NHZ8

Q8NHZ8
type: UnificationXref
id: Q8NHZ8
db: UniProt Knowledgebase

Mad1:C-Mad2
type: Complex
xref: Q9Y6D9
xref: Q13257
xref: GO:0043234

Q60566
type: UnificationXref
id: Q60566
db: UniProt Knowledgebase

RIGHT 0 conversion R6 Cdc20 CMad2 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdc20_CMad2
stoichiometric coefficient: 1.0

APC
type: PhysicalEntity
member physical entity: APC
cellular location: Cytoplasm

RIGHT 0 conversion R8 APC Cdc20 STOICHIOMETRY
type: Stoichiometry
physical entity: APC_Cdc20
stoichiometric coefficient: 1.0