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        <p>This is a model of the coupled Natch, Wnt and FGF modules as described in:      <br/>
                <b>A. Goldbeter and O. Pourquié</b>
          ,      <em>Modeling the segmentation clock as a network of coupled oscillations in the Notch, Wnt and FGF signaling pathways.</em>
          J Theor Biol. 2008 Jun 7;252(3):574-85, pubmed ID:      <a href="http://www.ncbi.nlm.nih.gov/pubmed/18308339">18308339</a>
                <br/>
          To uncouple the modules remove the reaction      <em>MAx_trans_Xa</em>
          and set      <em>vsFK=vsF</em>
          .      <br/>
          The SBML version of the model was converted from the CellML      <a href="http://www.cellml.org/models/goldbeter_pourquie_2008_version02">version</a>
          by Catherine Lloyd for the      <a href="http://www.cellml.org/models">CellML repository</a>
          .      </p>
            <br/>
            <p>To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to      <a href="http://creativecommons.org/publicdomain/zero/1.0/" title="Creative Commons CC0">CC0 Public Domain Dedication</a>
          for more information.      </p>
            <p>In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not.</p>
            <br/>
            <p>To cite BioModels Database, please use:      <a href="http://www.ncbi.nlm.nih.gov/pubmed/20587024" class="external">Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.</a>
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	<rdf:li rdf:resource="http://identifiers.org/interpro/IPR008349"/>
	</rdf:Bag>
	</bqbiol:isVersionOf>
	</rdf:Description>
	
          </rdf:RDF>
        </annotation>
            </species>
      <species boundaryCondition="true" compartment="cytosol" id="Xi" metaid="metaid_0000115" name="inactive TF X" sboTerm="SBO:0000252">
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
            <rdf:Description rdf:about="#metaid_0000115">
	<bqbiol:isVersionOf>
	<rdf:Bag>
	<rdf:li rdf:resource="http://identifiers.org/interpro/IPR006715"/>
	</rdf:Bag>
	</bqbiol:isVersionOf>
	</rdf:Description>
	
          </rdf:RDF>
        </annotation>
            </species>
      <species compartment="cytosol" id="Rast" initialConcentration="2" metaid="metaid_0000116" name="Ras total" sboTerm="SBO:0000252">
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
            <rdf:Description rdf:about="#metaid_0000116">
	<bqbiol:isVersionOf>
	<rdf:Bag>
	<rdf:li rdf:resource="http://identifiers.org/interpro/IPR001806"/>
	</rdf:Bag>
	</bqbiol:isVersionOf>
	</rdf:Description>
	
          </rdf:RDF>
        </annotation>
            </species>
      <species compartment="cytosol" id="ERKt" initialConcentration="2" metaid="metaid_0000117" name="ERK total" sboTerm="SBO:0000252">
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
            <rdf:Description rdf:about="#metaid_0000117">
	<bqbiol:isVersionOf>
	<rdf:Bag>
	<rdf:li rdf:resource="http://identifiers.org/interpro/IPR008349"/>
	</rdf:Bag>
	</bqbiol:isVersionOf>
	</rdf:Description>
	
          </rdf:RDF>
        </annotation>
            </species>
      <species compartment="cytosol" id="Xt" initialConcentration="2" metaid="metaid_0000118" name="X total" sboTerm="SBO:0000252">
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
            <rdf:Description rdf:about="#metaid_0000118">
	<bqbiol:isVersionOf>
	<rdf:Bag>
	<rdf:li rdf:resource="http://identifiers.org/interpro/IPR006715"/>
	</rdf:Bag>
	</bqbiol:isVersionOf>
	</rdf:Description>
	
          </rdf:RDF>
        </annotation>
            </species>
      <species compartment="cytosol" id="D" initialConcentration="2" metaid="metaid_0000119" name="Dsh protein" sboTerm="SBO:0000252">
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
            <rdf:Description rdf:about="#metaid_0000119">
              <bqbiol:isVersionOf>
	<rdf:Bag>
	<rdf:li rdf:resource="http://identifiers.org/interpro/IPR003351"/>
	</rdf:Bag>
	</bqbiol:isVersionOf>
	
	<bqbiol:isHomologTo>
	<rdf:Bag>
	<rdf:li rdf:resource="http://identifiers.org/uniprot/O14640"/>
	</rdf:Bag>
	</bqbiol:isHomologTo>
	</rdf:Description>
	
          </rdf:RDF>
        </annotation>
            </species>
      <species boundaryCondition="true" compartment="cytosol" id="AK" metaid="metaid_0000120" name="Axin2/Gsk3 destruction complex" sboTerm="SBO:0000297">
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
            <rdf:Description rdf:about="#metaid_0000120">
	<bqbiol:hasPart>
	<rdf:Bag>
	<rdf:li rdf:resource="http://identifiers.org/uniprot/Q9Y2T1"/>
	<rdf:li rdf:resource="http://identifiers.org/uniprot/P49841"/>
	</rdf:Bag>
	</bqbiol:hasPart>
	</rdf:Description>
	
          </rdf:RDF>
        </annotation>
            </species>
      <species compartment="cytosol" constant="true" id="Kt" initialConcentration="3" metaid="metaid_0000047" name="Kt" sboTerm="SBO:0000252">
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
            <rdf:Description rdf:about="#metaid_0000047">
	<bqbiol:isHomologTo>
	<rdf:Bag>
	<rdf:li rdf:resource="http://identifiers.org/uniprot/P49841"/>
	</rdf:Bag>
	</bqbiol:isHomologTo>
	</rdf:Description>
	
          </rdf:RDF>
        </annotation>
            </species>
      <species compartment="cytosol" constant="true" id="Fgf" initialConcentration="1" metaid="metaid_0000075" name="Fgf" sboTerm="SBO:0000252">
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
            <rdf:Description rdf:about="#metaid_0000075">
	<bqbiol:isVersionOf>
	<rdf:Bag>
	<rdf:li rdf:resource="http://identifiers.org/interpro/IPR017338"/>
	</rdf:Bag>
	</bqbiol:isVersionOf>
	</rdf:Description>
	
          </rdf:RDF>
        </annotation>
            </species>
    </listOfSpecies>
    <listOfParameters>
      <parameter id="KdN" metaid="metaid_0000009" name="KdN" sboTerm="SBO:0000027" units="nanomolar" value="1.4"/>
      <parameter id="vsN" metaid="metaid_0000010" name="vsN" sboTerm="SBO:0000048" units="flux" value="0.23"/>
      <parameter id="vdN" metaid="metaid_0000011" name="vdN" sboTerm="SBO:0000324" units="flux" value="2.82"/>
      <parameter id="KdNa" metaid="metaid_0000013" name="KdNa" sboTerm="SBO:0000027" units="nanomolar" value="0.001"/>
      <parameter id="VdNa" metaid="metaid_0000014" name="VdNa" sboTerm="SBO:0000186" units="flux" value="0.01"/>
      <parameter id="kt1" metaid="metaid_0000015" name="kt1" sboTerm="SBO:0000022" units="first_order_rate_constant" value="0.1"/>
      <parameter id="kt2" metaid="metaid_0000016" name="kt2" sboTerm="SBO:0000032" units="first_order_rate_constant" value="0.1"/>
      <parameter id="KdNan" metaid="metaid_0000017" name="KdNan" sboTerm="SBO:0000027" units="nanomolar" value="0.001"/>
      <parameter id="VdNan" metaid="metaid_0000018" name="VdNan" sboTerm="SBO:0000186" units="flux" value="0.1"/>
      <parameter id="KdMF" metaid="metaid_0000019" name="KdMF" sboTerm="SBO:0000027" units="nanomolar" value="0.768"/>
      <parameter id="KIG1" metaid="metaid_0000020" name="KIG1" units="nanomolar" value="2.5"/>
      <parameter constant="false" id="vsFK" metaid="metaid_0000021" name="vsFK" sboTerm="SBO:0000186" units="flux"/>
      <parameter id="vsF" metaid="metaid_0000022" name="vsF" sboTerm="SBO:0000186" units="flux" value="3"/>
      <parameter id="vmF" metaid="metaid_0000023" name="vmF" sboTerm="SBO:0000186" units="flux" value="1.92"/>
      <parameter id="KA" metaid="metaid_0000024" name="KA" units="nanomolar" value="0.05"/>
      <parameter id="KdF" metaid="metaid_0000025" name="KdF" sboTerm="SBO:0000027" units="nanomolar" value="0.37"/>
      <parameter id="vdF" metaid="metaid_0000026" name="vdF" sboTerm="SBO:0000186" units="flux" value="0.39"/>
      <parameter id="ksF" metaid="metaid_0000027" name="ksF" sboTerm="SBO:0000022" units="first_order_rate_constant" value="0.3"/>
      <parameter id="kd1" metaid="metaid_0000028" name="kd1" sboTerm="SBO:0000022" units="first_order_rate_constant" value="0"/>
      <parameter id="vsB" metaid="metaid_0000029" name="vsB" sboTerm="SBO:0000186" units="flux" value="0.087"/>
      <parameter id="kd2" metaid="metaid_0000030" name="kd2" sboTerm="SBO:0000022" units="first_order_rate_constant" value="7.062"/>
      <parameter id="v0" metaid="metaid_0000031" name="v0" sboTerm="SBO:0000186" units="flux" value="0.06"/>
      <parameter id="vMB" metaid="metaid_0000032" name="vMB" sboTerm="SBO:0000186" units="flux" value="1.64"/>
      <parameter id="vmd" metaid="metaid_0000033" name="vmd" sboTerm="SBO:0000186" units="flux" value="0.8"/>
      <parameter id="KaB" metaid="metaid_0000034" name="KaB" units="nanomolar" value="0.7"/>
      <parameter id="KaXa" metaid="metaid_0000035" name="KaXa" sboTerm="SBO:0000027" units="nanomolar" value="0.05"/>
      <parameter id="Kmd" metaid="metaid_0000036" name="Kmd" units="nanomolar" value="0.48"/>
      <parameter id="n" metaid="metaid_0000037" name="n" sboTerm="SBO:0000190" units="dimensionless" value="2"/>
      <parameter id="m" metaid="metaid_0000038" name="m" sboTerm="SBO:0000190" units="dimensionless" value="2"/>
      <parameter id="vMXa" metaid="metaid_0000039" name="vMXa" sboTerm="SBO:0000186" units="flux" value="0.5"/>
      <parameter id="ksAx" metaid="metaid_0000040" name="ksAx" sboTerm="SBO:0000022" units="first_order_rate_constant" value="0.02"/>
      <parameter id="vdAx" metaid="metaid_0000041" name="vdAx" sboTerm="SBO:0000186" units="flux" value="0.6"/>
      <parameter id="KdAx" metaid="metaid_0000042" name="KdAx" sboTerm="SBO:0000027" units="nanomolar" value="0.63"/>
      <parameter id="d1" metaid="metaid_0000048" name="d1" sboTerm="SBO:0000338" units="first_order_rate_constant" value="0.1"/>
      <parameter id="a1" metaid="metaid_0000049" name="a1" sboTerm="SBO:0000023" units="second_order_rate_constant" value="1.8"/>
      <parameter id="K1" metaid="metaid_0000050" name="K1" sboTerm="SBO:0000027" units="nanomolar" value="0.28"/>
      <parameter id="K2" metaid="metaid_0000051" name="K2" sboTerm="SBO:0000027" units="nanomolar" value="0.03"/>
      <parameter id="kt3" metaid="metaid_0000052" name="kt3" sboTerm="SBO:0000022" units="first_order_rate_constant" value="0.7"/>
      <parameter id="kt4" metaid="metaid_0000053" name="kt4" sboTerm="SBO:0000032" units="first_order_rate_constant" value="1.5"/>
      <parameter id="ksDusp" metaid="metaid_0000056" name="ksDusp" sboTerm="SBO:0000022" units="first_order_rate_constant" value="0.5"/>
      <parameter id="vdDusp" metaid="metaid_0000057" name="vdDusp" sboTerm="SBO:0000186" units="flux" value="2"/>
      <parameter id="KdDusp" metaid="metaid_0000058" name="KdDusp" sboTerm="SBO:0000027" units="nanomolar" value="0.5"/>
      <parameter id="kcDusp" metaid="metaid_0000067" name="kcDusp" sboTerm="SBO:0000022" units="first_order_rate_constant" value="1.35"/>
      <parameter id="KaFgf" metaid="metaid_0000076" name="KaFgf" sboTerm="SBO:0000191" units="nanomolar" value="0.5"/>
      <parameter id="KaRas" metaid="metaid_0000077" name="KaRas" sboTerm="SBO:0000027" units="nanomolar" value="0.103"/>
      <parameter id="KdRas" metaid="metaid_0000078" name="KdRas" sboTerm="SBO:0000027" units="nanomolar" value="0.1"/>
      <parameter id="KdErk" metaid="metaid_0000079" name="KdErk" sboTerm="SBO:0000027" units="nanomolar" value="0.05"/>
      <parameter id="KaErk" metaid="metaid_0000080" name="KaErk" sboTerm="SBO:0000027" units="nanomolar" value="0.05"/>
      <parameter id="KaX" metaid="metaid_0000081" name="KaX" sboTerm="SBO:0000027" units="nanomolar" value="0.05"/>
      <parameter id="KIF" metaid="metaid_0000082" name="KIF" sboTerm="SBO:0000191" units="nanomolar" value="0.5"/>
      <parameter id="KID" metaid="metaid_0000083" name="KID" sboTerm="SBO:0000027" units="nanomolar" value="0.5"/>
      <parameter id="KdX" metaid="metaid_0000084" name="KdX" sboTerm="SBO:0000027" units="nanomolar" value="0.05"/>
      <parameter id="KaMDusp" metaid="metaid_0000085" name="KaMDusp" sboTerm="SBO:0000191" units="nanomolar" value="0.5"/>
      <parameter id="KdMDusp" metaid="metaid_0000086" name="KdMDusp" sboTerm="SBO:0000027" units="nanomolar" value="0.5"/>
      <parameter id="q" metaid="metaid_0000087" name="q" sboTerm="SBO:0000190" units="dimensionless" value="2"/>
      <parameter id="r" metaid="metaid_0000088" name="r" sboTerm="SBO:0000191" units="dimensionless" value="2"/>
      <parameter id="kc" metaid="metaid_0000089" name="kc" sboTerm="SBO:0000022" units="first_order_rate_constant" value="3.45"/>
      <parameter id="j" metaid="metaid_0000090" name="j" sboTerm="SBO:0000191" units="dimensionless" value="2"/>
      <parameter id="p" metaid="metaid_0000091" name="p" sboTerm="SBO:0000191" units="dimensionless" value="2"/>
      <parameter id="epsilon" metaid="metaid_0000092" name="epsilon" sboTerm="SBO:0000381" units="dimensionless" value="0.3"/>
      <parameter id="theta" metaid="metaid_0000093" name="theta" sboTerm="SBO:0000381" units="dimensionless" value="1.5"/>
      <parameter id="eta" metaid="metaid_0000094" name="eta" sboTerm="SBO:0000381" units="dimensionless" value="0.3"/>
      <parameter id="VMsMDusp" metaid="metaid_0000136" name="VMsMDusp" sboTerm="SBO:0000186" units="flux" value="0.9"/>
      <parameter id="VMdMDusp" metaid="metaid_0000137" name="VMdMDusp" sboTerm="SBO:0000186" units="flux" value="0.5"/>
      <parameter id="VMK" metaid="metaid_0000138" name="VMK" sboTerm="SBO:0000186" units="flux" value="5.08"/>
      <parameter id="VMP" metaid="metaid_0000139" name="VMP" sboTerm="SBO:0000186" units="flux" value="1"/>
      <parameter id="VMaRas" metaid="metaid_0000140" name="VMaRas" sboTerm="SBO:0000186" units="flux" value="4.968"/>
      <parameter id="VMdRas" metaid="metaid_0000141" name="VMdRas" sboTerm="SBO:0000186" units="flux" value="0.41"/>
      <parameter id="VMaErk" metaid="metaid_0000142" name="VMaErk" sboTerm="SBO:0000186" units="flux" value="3.3"/>
      <parameter id="VMaX" metaid="metaid_0000143" name="VMaX" sboTerm="SBO:0000186" units="flux" value="1.6"/>
      <parameter id="VMdX" metaid="metaid_0000144" name="VMdX" sboTerm="SBO:0000186" units="flux" value="0.5"/>
    </listOfParameters>
    <listOfRules>
      <assignmentRule metaid="metaid_0000122" variable="vsFK">
        <math xmlns="http://www.w3.org/1998/Math/MathML">        
          <apply>
            <times/>
            <ci> vsF </ci>
            <apply>
              <divide/>
              <ci> KIG1 </ci>
              <apply>
                <plus/>
                <ci> KIG1 </ci>
                <ci> K </ci>
              </apply>
            </apply>
          </apply>
        </math>
            </assignmentRule>
      <assignmentRule metaid="metaid_0000123" variable="AK">
        <math xmlns="http://www.w3.org/1998/Math/MathML">        
          <apply>
            <minus/>
            <ci> Kt </ci>
            <ci> K </ci>
          </apply>
        </math>
            </assignmentRule>
      <assignmentRule metaid="metaid_0000128" variable="Rasi">
        <math xmlns="http://www.w3.org/1998/Math/MathML">        
          <apply>
            <minus/>
            <ci> Rast </ci>
            <ci> Rasa </ci>
          </apply>
        </math>
            </assignmentRule>
      <assignmentRule metaid="metaid_0000131" variable="ERKi">
        <math xmlns="http://www.w3.org/1998/Math/MathML">        
          <apply>
            <minus/>
            <ci> ERKt </ci>
            <ci> ERKa </ci>
          </apply>
        </math>
            </assignmentRule>
      <assignmentRule metaid="metaid_0000134" variable="Xi">
        <math xmlns="http://www.w3.org/1998/Math/MathML">        
          <apply>
            <minus/>
            <ci> Xt </ci>
            <ci> Xa </ci>
          </apply>
        </math>
            </assignmentRule>
    </listOfRules>
    <listOfReactions>
      <reaction id="n_synth" metaid="metaid_0000155" name="Notch_synthesis" reversible="false">
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
            <rdf:Description rdf:about="#metaid_0000155">
	<bqbiol:isVersionOf>
	<rdf:Bag>
	<rdf:li rdf:resource="http://identifiers.org/go/GO:0010467"/>
	</rdf:Bag>
	</bqbiol:isVersionOf>
	</rdf:Description>
	
          </rdf:RDF>
        </annotation>
              <listOfProducts>
          <speciesReference metaid="_389874" species="N"/>
        </listOfProducts>
        <kineticLaw metaid="_389886">
          <math xmlns="http://www.w3.org/1998/Math/MathML">          
            <apply>
              <times/>
              <ci> cytosol </ci>
              <ci> epsilon </ci>
              <ci> vsN </ci>
            </apply>
          </math>
                </kineticLaw>
      </reaction>
      <reaction id="N_degradation" metaid="metaid_0000156" name="N_degradation" reversible="false" sboTerm="SBO:0000179">
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
            <rdf:Description rdf:about="#metaid_0000156">
	<bqbiol:isVersionOf>
	<rdf:Bag>
	<rdf:li rdf:resource="http://identifiers.org/go/GO:0030163"/>
	</rdf:Bag>
	</bqbiol:isVersionOf>
	</rdf:Description>
	
          </rdf:RDF>
        </annotation>
              <listOfReactants>
          <speciesReference metaid="_389898" species="N"/>
        </listOfReactants>
        <kineticLaw metaid="_389910">
          <math xmlns="http://www.w3.org/1998/Math/MathML">          
            <apply>
              <divide/>
              <apply>
                <times/>
                <ci> epsilon </ci>
                <ci> cytosol </ci>
                <ci> vdN </ci>
                <ci> N </ci>
              </apply>
              <apply>
                <plus/>
                <ci> KdN </ci>
                <ci> N </ci>
              </apply>
            </apply>
          </math>
                </kineticLaw>
      </reaction>
      <reaction id="N_activation" metaid="metaid_0000157" name="Notch_activation" reversible="false" sboTerm="SBO:0000178">
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
            <rdf:Description rdf:about="#metaid_0000157">
	<bqbiol:isVersionOf>
	<rdf:Bag>
	<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_691.2"/>
	<rdf:li rdf:resource="http://identifiers.org/go/GO:0007220"/>
	</rdf:Bag>
	</bqbiol:isVersionOf>
	</rdf:Description>
	
          </rdf:RDF>
        </annotation>
              <listOfReactants>
          <speciesReference metaid="_389922" species="N"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference metaid="_389934" species="Na"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference metaid="_389946" species="F"/>
        </listOfModifiers>
        <kineticLaw metaid="_389959">
          <math xmlns="http://www.w3.org/1998/Math/MathML">          
            <apply>
              <divide/>
              <apply>
                <times/>
                <ci> epsilon </ci>
                <ci> cytosol </ci>
                <ci> kc </ci>
                <ci> N </ci>
                <apply>
                  <power/>
                  <ci> KIF </ci>
                  <ci> j </ci>
                </apply>
              </apply>
              <apply>
                <plus/>
                <apply>
                  <power/>
                  <ci> KIF </ci>
                  <ci> j </ci>
                </apply>
                <apply>
                  <power/>
                  <ci> F </ci>
                  <ci> j </ci>
                </apply>
              </apply>
            </apply>
          </math>
                </kineticLaw>
      </reaction>
      <reaction id="Na_degradation" metaid="metaid_0000158" name="Na_degradation" reversible="false" sboTerm="SBO:0000179">
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
            <rdf:Description rdf:about="#metaid_0000158">
	<bqbiol:isVersionOf>
	<rdf:Bag>
	<rdf:li rdf:resource="http://identifiers.org/go/GO:0030163"/>
	</rdf:Bag>
	</bqbiol:isVersionOf>
	</rdf:Description>
	
          </rdf:RDF>
        </annotation>
              <listOfReactants>
          <speciesReference metaid="_389971" species="Na"/>
        </listOfReactants>
        <kineticLaw metaid="_389983">
          <math xmlns="http://www.w3.org/1998/Math/MathML">          
            <apply>
              <divide/>
              <apply>
                <times/>
                <ci> epsilon </ci>
                <ci> cytosol </ci>
                <ci> VdNa </ci>
                <ci> Na </ci>
              </apply>
              <apply>
                <plus/>
                <ci> KdNa </ci>
                <ci> Na </ci>
              </apply>
            </apply>
          </math>
                </kineticLaw>
      </reaction>
      <reaction id="Na_transport" metaid="metaid_0000159" sboTerm="SBO:0000185">
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
            <rdf:Description rdf:about="#metaid_0000159">
	<bqbiol:isVersionOf>
	<rdf:Bag>
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