P06493
type: UnificationXref
id: P06493
db: UniProt Knowledgebase

cdk1
type: Protein
xref: P06493

cdk2
type: Protein
xref: P24941

cyclinE degradation
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R10 C2 STOICHIOMETRY
xref: GO:0008054
left: C2

GO:0004693
type: UnificationXref
id: GO:0004693
db: Gene Ontology

MODEL1111382868
type: UnificationXref
id: MODEL1111382868
db: BioModels Database

GO:0000278
type: UnificationXref
id: GO:0000278
db: Gene Ontology

cyclinB
type: Protein
xref: Q8WWL7

Romond1999 CellCycle
type: Pathway
pathway component: Ubiquitin ligase mediated cyclinE degradation
pathway component: cdk2 mediated cyclinB synthesis
pathway component: Ubiquitin ligase mediated cyclinB degradation
pathway component: cyclinE degradation
pathway component: cyclinB degradation
pathway component: cyclinE synthesis
xref: hsa04110
xref: http://identifiers.org/pubmed/10415827
xref: BIOMD0000000207
xref: MODEL1111382868
xref: GO:0000278
organism: biosource 1
comment: This BioPAX Level3 file was automatically generated on 23-Jun-2017 by SBML2BioPAX-3.1, BioModels.net, EMBL-EBI.
comment: The original model, 'Romond1999_CellCycle', was published in BioModels Database (http://www.ebi.ac.uk/biomodels/).
data source: BioModels Database

cyclinE
type: Protein
xref: P24864

C2
type: PhysicalEntity
member physical entity: cyclinE
cellular location: compartment

P24941
type: UnificationXref
id: P24941
db: UniProt Knowledgebase

P24864
type: UnificationXref
id: P24864
db: UniProt Knowledgebase

http://identifiers.org/taxonomy/2759
type: UnificationXref
id: 2759
db: Taxonomy

compartment
type: CellularLocationVocabulary

C1
type: PhysicalEntity
member physical entity: cyclinB
cellular location: compartment

LEFT 0 conversion R9 C2 STOICHIOMETRY
type: Stoichiometry
physical entity: C2
stoichiometric coefficient: 1.0

ubiquitin ligase
type: Protein
xref: Q9UBT2

Ubiquitin ligase 2
type: Protein
xref: Q9UBT2

BIOMD0000000207
type: UnificationXref
id: BIOMD0000000207
db: BioModels Database

LEFT 0 conversion R3 C1 STOICHIOMETRY
type: Stoichiometry
physical entity: C1
stoichiometric coefficient: 1.0

Q9UBT2
type: UnificationXref
id: Q9UBT2
db: UniProt Knowledgebase

BioModels Database
type: Provenance
xref: BIOMD0000000207

hsa04110
type: UnificationXref
id: hsa04110
db: KEGG Pathway

LEFT 0 conversion R10 C2 STOICHIOMETRY
type: Stoichiometry
physical entity: C2
stoichiometric coefficient: 1.0

cdk2 mediated cyclinB synthesis
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R1 C1 STOICHIOMETRY
xref: GO:0004693
right: C1

Ubiquitin ligase mediated cyclinB degradation
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R2 C1 STOICHIOMETRY
xref: GO:0008054
left: C1

RIGHT 0 conversion R1 C1 STOICHIOMETRY
type: Stoichiometry
physical entity: C1
stoichiometric coefficient: 1.0

LEFT 0 conversion R2 C1 STOICHIOMETRY
type: Stoichiometry
physical entity: C1
stoichiometric coefficient: 1.0

cyclinB degradation
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R3 C1 STOICHIOMETRY
xref: GO:0008054
left: C1

Q8WWL7
type: UnificationXref
id: Q8WWL7
db: UniProt Knowledgebase

C1
type: PhysicalEntity
member physical entity: cyclinB
cellular location: compartment

BioModels Database
type: Provenance
xref: MODEL1111382868

cyclinE synthesis
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R8 C2 STOICHIOMETRY
right: C2

Ubiquitin ligase mediated cyclinE degradation
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R9 C2 STOICHIOMETRY
xref: GO:0008054
left: C2

http://identifiers.org/pubmed/10415827
type: PublicationXref
id: 10415827
db: PubMed

C2
type: PhysicalEntity
member physical entity: cyclinE
cellular location: compartment

C2
type: PhysicalEntity
member physical entity: cyclinE
cellular location: compartment

GO:0008054
type: UnificationXref
id: GO:0008054
db: Gene Ontology

RIGHT 0 conversion R8 C2 STOICHIOMETRY
type: Stoichiometry
physical entity: C2
stoichiometric coefficient: 1.0

C1
type: PhysicalEntity
member physical entity: cyclinB
cellular location: compartment