y5
type: PhysicalEntity
member physical entity: active cycE_cdk2
cellular location: compartment

GO:0003700
type: UnificationXref
id: GO:0003700
db: Gene Ontology

y4
type: PhysicalEntity
member physical entity: inactive cycE_cdk2
cellular location: compartment

y1
type: PhysicalEntity
member physical entity: E2F
cellular location: compartment

y3
type: PhysicalEntity
member physical entity: Phosphorylated pRB
cellular location: compartment

GO:0006412
type: UnificationXref
id: GO:0006412
db: Gene Ontology

GO:0000278
type: UnificationXref
id: GO:0000278
db: Gene Ontology

RIGHT 0 conversion R4 y3 STOICHIOMETRY
type: Stoichiometry
physical entity: y3
stoichiometric coefficient: 1.0

Q01094
type: UnificationXref
id: Q01094
db: UniProt Knowledgebase

GO:0000082
type: UnificationXref
id: GO:0000082
db: Gene Ontology

compartment
type: CellularLocationVocabulary

RIGHT 0 conversion R9 y5 STOICHIOMETRY
type: Stoichiometry
physical entity: y5
stoichiometric coefficient: 1.0

y1
type: PhysicalEntity
member physical entity: E2F
cellular location: compartment

RIGHT 0 conversion R1 y1 STOICHIOMETRY
type: Stoichiometry
physical entity: y1
stoichiometric coefficient: 1.0

RIGHT 0 conversion R3 y2 STOICHIOMETRY
type: Stoichiometry
physical entity: y2
stoichiometric coefficient: 1.0

RIGHT 0 conversion R7 y4 STOICHIOMETRY
type: Stoichiometry
physical entity: y4
stoichiometric coefficient: 1.0

y5
type: PhysicalEntity
member physical entity: active cycE_cdk2
cellular location: compartment

y2
type: PhysicalEntity
member physical entity: pRB
cellular location: compartment

y4
type: PhysicalEntity
member physical entity: inactive cycE_cdk2
cellular location: compartment

P05412
type: UnificationXref
id: P05412
db: UniProt Knowledgebase

RIGHT 0 conversion R8 y4 STOICHIOMETRY
type: Stoichiometry
physical entity: y4
stoichiometric coefficient: 1.0

RIGHT 0 conversion R13 y6 STOICHIOMETRY
type: Stoichiometry
physical entity: y6
stoichiometric coefficient: 1.0

LEFT 0 conversion R10 y5 STOICHIOMETRY
type: Stoichiometry
physical entity: y5
stoichiometric coefficient: 1.0

MODEL1475866846
type: UnificationXref
id: MODEL1475866846
db: BioModels Database

LEFT 0 conversion R11 y4 STOICHIOMETRY
type: Stoichiometry
physical entity: y4
stoichiometric coefficient: 1.0

RIGHT 0 conversion R10 y4 STOICHIOMETRY
type: Stoichiometry
physical entity: y4
stoichiometric coefficient: 1.0

y5
type: PhysicalEntity
member physical entity: active cycE_cdk2
cellular location: compartment

http://identifiers.org/pubmed/14582399
type: PublicationXref
id: 14582399
db: PubMed

y2
type: PhysicalEntity
member physical entity: pRB
cellular location: compartment

RIGHT 0 conversion R14 y6 STOICHIOMETRY
type: Stoichiometry
physical entity: y6
stoichiometric coefficient: 1.0

LEFT 0 conversion R5 y2 STOICHIOMETRY
type: Stoichiometry
physical entity: y2
stoichiometric coefficient: 1.0

R11
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion R11 y4 STOICHIOMETRY
spontaneous: true
left: y4
conversion direction: RIGHT_TO_LEFT

R10
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R10 y4 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R10 y5 STOICHIOMETRY
right: y4
left: y5

GO:0004693
type: UnificationXref
id: GO:0004693
db: Gene Ontology

R13
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R13 y6 STOICHIOMETRY
xref: GO:0003700
xref: GO:0045727
right: y6

Deineko2003 CellCycle
type: Pathway
pathway component: R1
pathway component: R11
pathway component: R2
pathway component: R10
pathway component: R3
pathway component: R13
pathway component: R4
pathway component: R12
pathway component: R5
pathway component: R15
pathway component: R6
pathway component: R14
pathway component: R7
pathway component: R8
pathway component: R9
xref: hsa04110
xref: http://identifiers.org/pubmed/14582399
xref: BIOMD0000000208
xref: GO:0000278
xref: MODEL1475866846
organism: biosource 1
comment: This BioPAX Level3 file was automatically generated on 23-Jun-2017 by SBML2BioPAX-3.1, BioModels.net, EMBL-EBI.
comment: The original model, 'Deineko2003_CellCycle', was published in BioModels Database (http://www.ebi.ac.uk/biomodels/).
data source: BioModels Database

R12
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion R12 y5 STOICHIOMETRY
xref: GO:0019941
spontaneous: true
left: y5
conversion direction: RIGHT_TO_LEFT

GO:0045727
type: UnificationXref
id: GO:0045727
db: Gene Ontology

R15
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R15 y6 STOICHIOMETRY
xref: GO:0019941
left: y6

R14
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R14 y6 STOICHIOMETRY
xref: GO:0006412
right: y6

LEFT 0 conversion R15 y6 STOICHIOMETRY
type: Stoichiometry
physical entity: y6
stoichiometric coefficient: 1.0

http://identifiers.org/taxonomy/40674
type: UnificationXref
id: 40674
db: Taxonomy

P24941
type: UnificationXref
id: P24941
db: UniProt Knowledgebase

y6
type: PhysicalEntity
member physical entity: AP-1
cellular location: compartment

P24864
type: UnificationXref
id: P24864
db: UniProt Knowledgebase

E2F
type: Protein
xref: Q01094

LEFT 0 conversion R9 y4 STOICHIOMETRY
type: Stoichiometry
physical entity: y4
stoichiometric coefficient: 1.0

pRB
type: Protein
xref: P06400

GO:0019941
type: UnificationXref
id: GO:0019941
db: Gene Ontology

BIOMD0000000208
type: UnificationXref
id: BIOMD0000000208
db: BioModels Database

Phosphorylated pRB
type: Protein
xref: P06400

inactive cycE_cdk2
type: Complex
xref: P24941
xref: P24864

y2
type: PhysicalEntity
member physical entity: pRB
cellular location: compartment

active cycE_cdk2
type: Complex
xref: P24941
xref: P24864

AP-1
type: Protein
xref: P05412

LEFT 0 conversion R12 y5 STOICHIOMETRY
type: Stoichiometry
physical entity: y5
stoichiometric coefficient: 1.0

BioModels Database
type: Provenance
xref: BIOMD0000000208

hsa04110
type: UnificationXref
id: hsa04110
db: KEGG Pathway

y4
type: PhysicalEntity
member physical entity: inactive cycE_cdk2
cellular location: compartment

y4
type: PhysicalEntity
member physical entity: inactive cycE_cdk2
cellular location: compartment

y6
type: PhysicalEntity
member physical entity: AP-1
cellular location: compartment

P06400
type: UnificationXref
id: P06400
db: UniProt Knowledgebase

R1
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R1 y1 STOICHIOMETRY
xref: GO:0006412
right: y1

R2
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R2 y1 STOICHIOMETRY
xref: GO:0019941
left: y1

R3
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R3 y2 STOICHIOMETRY
xref: GO:0003700
xref: GO:0045727
right: y2

R4
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R4 y2 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R4 y3 STOICHIOMETRY
xref: GO:0004693
right: y3
left: y2

R5
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R5 y2 STOICHIOMETRY
xref: GO:0019941
left: y2

y4
type: PhysicalEntity
member physical entity: inactive cycE_cdk2
cellular location: compartment

R6
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R6 y3 STOICHIOMETRY
xref: GO:0019941
left: y3

R7
type: ComplexAssembly
participant stoichiometry: RIGHT 0 conversion R7 y4 STOICHIOMETRY
xref: GO:0003700
xref: GO:0045727
right: y4
spontaneous: true
conversion direction: LEFT_TO_RIGHT

BioModels Database
type: Provenance
xref: MODEL1475866846

R8
type: ComplexAssembly
participant stoichiometry: RIGHT 0 conversion R8 y4 STOICHIOMETRY
xref: GO:0003700
xref: GO:0045727
right: y4
spontaneous: true
conversion direction: LEFT_TO_RIGHT

R9
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R9 y4 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R9 y5 STOICHIOMETRY
xref: GO:0000082
right: y5
left: y4

y6
type: PhysicalEntity
member physical entity: AP-1
cellular location: compartment

LEFT 0 conversion R4 y2 STOICHIOMETRY
type: Stoichiometry
physical entity: y2
stoichiometric coefficient: 1.0

LEFT 0 conversion R6 y3 STOICHIOMETRY
type: Stoichiometry
physical entity: y3
stoichiometric coefficient: 1.0

LEFT 0 conversion R2 y1 STOICHIOMETRY
type: Stoichiometry
physical entity: y1
stoichiometric coefficient: 1.0

y3
type: PhysicalEntity
member physical entity: Phosphorylated pRB
cellular location: compartment