% This file works with OCTAVE and is automatically generated with 
% the System Biology Format Converter (http://sbfc.sourceforge.net/)
% from an SBML file.
% To run this file with Matlab you must edit the comments providing
% the definition of the ode solver and the signature for the 
% xdot function.
%
% The conversion system has the following limitations:
%  - You may have to re order some reactions and Assignment Rules definition
%  - Delays are not taken into account
%  - You should change the lsode parameters (start, end, steps) to get better results
%

%
% Model name = Lee2010_ThrombinActivation_OneForm_minimal
%
% is http://identifiers.org/biomodels.db/MODEL1108260004
% is http://identifiers.org/biomodels.db/BIOMD0000000363
% isDescribedBy http://identifiers.org/pubmed/20435402
% isDerivedFrom http://identifiers.org/pubmed/17726029
%


function main()
%Initial conditions vector
	x0=zeros(4,1);
	x0(1) = 1.0;
	x0(2) = 0.0;
	x0(3) = 0.0;
	x0(4) = 0.0;


% Depending on whether you are using Octave or Matlab,
% you should comment / uncomment one of the following blocks.
% This should also be done for the definition of the function f below.
% Start Matlab code
%	tspan=[0:0.01:100];
%	opts = odeset('AbsTol',1e-3);
%	[t,x]=ode23tb(@f,tspan,x0,opts);
% End Matlab code

% Start Octave code
	t=linspace(0,100,100);
	x=lsode('f',x0,t);
% End Octave code


	plot(t,x);
end



% Depending on whether you are using Octave or Matlab,
% you should comment / uncomment one of the following blocks.
% This should also be done for the definition of the function f below.
% Start Matlab code
%function xdot=f(t,x)
% End Matlab code

% Start Octave code
function xdot=f(x,t)
% End Octave code

% Compartment: id = compartment, name = compartment, constant
	compartment_compartment=1.0;

% Reaction: id = r1, name = r1	% Local Parameter:   id =  k1, name = k1
	reaction_r1_k1=0.005;

	reaction_r1=compartment_compartment*reaction_r1_k1*x(1);

% Reaction: id = r2, name = r2	% Local Parameter:   id =  k1, name = k1
	reaction_r2_k1=0.01;

	reaction_r2=compartment_compartment*reaction_r2_k1*x(2);

% Reaction: id = r3, name = r3	% Local Parameter:   id =  k1, name = k1
	reaction_r3_k1=1.0E-5;

	reaction_r3=compartment_compartment*reaction_r3_k1*x(1);

% Reaction: id = r4, name = r4	% Local Parameter:   id =  k1, name = k1
	reaction_r4_k1=2.5E-5;

	reaction_r4=compartment_compartment*reaction_r4_k1*x(4);

	xdot=zeros(4,1);
	
% Species:   id = II, name = II, affected by kineticLaw
	xdot(1) = (1/(compartment_compartment))*((-1.0 * reaction_r1) + (-1.0 * reaction_r3));
	
% Species:   id = M, name = M, affected by kineticLaw
	xdot(2) = (1/(compartment_compartment))*(( 1.0 * reaction_r1) + (-1.0 * reaction_r2));
	
% Species:   id = IIa, name = IIa, affected by kineticLaw
	xdot(3) = (1/(compartment_compartment))*(( 1.0 * reaction_r2) + ( 1.0 * reaction_r4));
	
% Species:   id = P2, name = P2, affected by kineticLaw
	xdot(4) = (1/(compartment_compartment))*(( 1.0 * reaction_r3) + (-1.0 * reaction_r4));
end

% adding few functions representing operators used in SBML but not present directly 
% in either matlab or octave. 
function z=pow(x,y),z=x^y;end
function z=root(x,y),z=y^(1/x);end
function z = piecewise(varargin)
	numArgs = nargin;
	result = 0;
	foundResult = 0;
	for k=1:2: numArgs-1
		if varargin{k+1} == 1
			result = varargin{k};
			foundResult = 1;
			break;
		end
	end
	if foundResult == 0
		result = varargin{numArgs};
	end
	z = result;
end


