Q3MHS8
type: UnificationXref
id: Q3MHS8
db: UniProt Knowledgebase

s128
type: PhysicalEntity
member physical entity: Complex_br_(Cubitus_space_interruptus_space_repressor/Su(fu))
cellular location: nucleus

LEFT 0 conversion r14 s69 STOICHIOMETRY
type: Stoichiometry
physical entity: s69
stoichiometric coefficient: 1.0

RIGHT 0 conversion re24 s159 STOICHIOMETRY
type: Stoichiometry
physical entity: s159
stoichiometric coefficient: 1.0

s7
type: PhysicalEntity
member physical entity: Hedgehog
cellular location: default

GO:0007228
type: UnificationXref
id: GO:0007228
db: Gene Ontology

re24
type: Transport
participant stoichiometry: RIGHT 0 conversion re24 s159 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion re24 s148 STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion re24 s150 STOICHIOMETRY
right: s159
left: s150
left: s148

RIGHT 0 conversion r25 s161 STOICHIOMETRY
type: Stoichiometry
physical entity: s161
stoichiometric coefficient: 1.0

complex
type: PhysicalEntity
xref: GO:0043234

GO:0007224
type: UnificationXref
id: GO:0007224
db: Gene Ontology

Q13635
type: UnificationXref
id: Q13635
db: UniProt Knowledgebase

MIcrotubule
type: PhysicalEntity
xref: GO:0005874

RIGHT 0 conversion r53 s70 STOICHIOMETRY
type: Stoichiometry
physical entity: s70
stoichiometric coefficient: 1.0

RIGHT 0 conversion r26 s70 STOICHIOMETRY
type: Stoichiometry
physical entity: s70
stoichiometric coefficient: 1.0

RIGHT 1 conversion r23 s160 STOICHIOMETRY
type: Stoichiometry
physical entity: s160
stoichiometric coefficient: 1.0

s150
type: PhysicalEntity
member physical entity: complex
cellular location: Receiving cell

LEFT 1 conversion r54 s71 STOICHIOMETRY
type: Stoichiometry
physical entity: s71
stoichiometric coefficient: 1.0

LEFT 0 conversion re24 s148 STOICHIOMETRY
type: Stoichiometry
physical entity: s148
stoichiometric coefficient: 1.0

s70
type: PhysicalEntity
member physical entity: Cubitus_space_interruptus
cellular location: nucleus

s69
type: PhysicalEntity
member physical entity: Complex_br_(Costal2/Fused/_br_Smoothened)
cellular location: lipid raft

smoothened
type: PhysicalEntity

MODEL1101270001
type: UnificationXref
id: MODEL1101270001
db: BioModels Database

LEFT 0 conversion r26 s161 STOICHIOMETRY
type: Stoichiometry
physical entity: s161
stoichiometric coefficient: 1.0

Patched
type: Protein
xref: Q13635

RIGHT 0 conversion r52 s75 STOICHIOMETRY
type: Stoichiometry
physical entity: s75
stoichiometric coefficient: 1.0

s75
type: PhysicalEntity
member physical entity: Hedgehog target gene
cellular location: nucleus

Hedgehog
type: Protein
xref: Q15465

BIOMD0000000395
type: UnificationXref
id: BIOMD0000000395
db: BioModels Database

s160
type: PhysicalEntity
member physical entity: Complex_br_(Su(fu)/Fused/../_br_Smoothened)
cellular location: lipid raft

ATP
type: SmallMolecule
xref: CHEBI:15422

Receiving cell
type: CellularLocationVocabulary

Complex_br_(Sap18/Su(fu)/_br_Cubitus_space_interruptus_space_repressor)
type: PhysicalEntity
xref: GO:0043234

lipid raft
type: CellularLocationVocabulary

nucleus
type: CellularLocationVocabulary

CHEBI:16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Complex_br_(Costal2/Fused/_br_Smoothened)
type: PhysicalEntity
xref: GO:0043234

s159
type: PhysicalEntity
member physical entity: Complex_br_(Costal2/Fused/../microtubule)
cellular location: lipid raft

Sap18
type: Protein
xref: Q3MHS8

Complex_br_(Costal2/Smoothened/_br_Fused)
type: PhysicalEntity
xref: GO:0043234

Q92793
type: UnificationXref
id: Q92793
db: UniProt Knowledgebase

s140
type: PhysicalEntity
member physical entity: Complex_br_(Sap18/Su(fu)/_br_Cubitus_space_interruptus_space_repressor)
cellular location: nucleus

RIGHT 1 conversion r25 s69 STOICHIOMETRY
type: Stoichiometry
physical entity: s69
stoichiometric coefficient: 1.0

http://identifiers.org/taxonomy/40674
type: UnificationXref
id: 40674
db: Taxonomy

default
type: CellularLocationVocabulary

LEFT 0 conversion r52 s140 STOICHIOMETRY
type: Stoichiometry
physical entity: s140
stoichiometric coefficient: 1.0

P10523
type: UnificationXref
id: P10523
db: UniProt Knowledgebase

RIGHT 0 conversion r55 s75 STOICHIOMETRY
type: Stoichiometry
physical entity: s75
stoichiometric coefficient: 1.0

RIGHT 1 conversion r15 s10 STOICHIOMETRY
type: Stoichiometry
physical entity: s10
stoichiometric coefficient: 1.0

LEFT 0 conversion r51 s135 STOICHIOMETRY
type: Stoichiometry
physical entity: s135
stoichiometric coefficient: 1.0

GO:0043234
type: UnificationXref
id: GO:0043234
db: Gene Ontology

s48
type: PhysicalEntity
member physical entity: Complex_br_(Costal2/Smoothened/_br_Fused)
cellular location: Receiving cell

Complex_br_(Su(fu)/Cubitus)
type: PhysicalEntity

r15
type: BiochemicalReaction
participant stoichiometry: LEFT 1 conversion r15 s9 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion r15 s10 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion r15 s46 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion r15 s48 STOICHIOMETRY
right: s48
right: s10
left: s46
left: s9

B4NUI3
type: UnificationXref
id: B4NUI3
db: UniProt Knowledgebase

Complex_br_(Su(fu)/Fused/../_br_Smoothened)
type: PhysicalEntity
xref: GO:0043234

r14
type: Transport
participant stoichiometry: LEFT 0 conversion r14 s69 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion r14 s46 STOICHIOMETRY
right: s46
left: s69

LEFT 1 conversion r15 s9 STOICHIOMETRY
type: Stoichiometry
physical entity: s9
stoichiometric coefficient: 1.0

LEFT 0 conversion r23 s159 STOICHIOMETRY
type: Stoichiometry
physical entity: s159
stoichiometric coefficient: 1.0

s135
type: PhysicalEntity
member physical entity: Sap18
cellular location: nucleus

Microtubule
type: PhysicalEntity
xref: GO:0005874

Complex_br_(CBP/Cubitus)
type: PhysicalEntity
xref: GO:0043234

sag
type: Protein
xref: P10523

RIGHT 0 conversion r51 s140 STOICHIOMETRY
type: Stoichiometry
physical entity: s140
stoichiometric coefficient: 1.0

Complex_br_(Costal2/Fused/_br_Smoothened)
type: PhysicalEntity
xref: GO:0043234

Complex_br_(Costal2/Fused/../microtubule)
type: PhysicalEntity
xref: GO:0043234

s70
type: PhysicalEntity
member physical entity: Cubitus_space_interruptus
cellular location: nucleus

P00025
type: UnificationXref
id: P00025
db: PANTHER Pathway

RIGHT 0 conversion r23 s68 STOICHIOMETRY
type: Stoichiometry
physical entity: s68
stoichiometric coefficient: 1.0

RIGHT 0 conversion r15 s48 STOICHIOMETRY
type: Stoichiometry
physical entity: s48
stoichiometric coefficient: 1.0

s161
type: PhysicalEntity
member physical entity: Complex_br_(Su(fu)/Cubitus)
cellular location: Receiving cell

r23
type: Transport
participant stoichiometry: RIGHT 1 conversion r23 s160 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion r23 s159 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion r23 s68 STOICHIOMETRY
right: s160
right: s68
left: s159

CBP
type: Protein
xref: Q92793

r26
type: Transport
participant stoichiometry: LEFT 0 conversion r26 s161 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion r26 s70 STOICHIOMETRY
right: s70
left: s161

Cubitus_space_interruptus
type: Protein
xref: B4NUI3

RIGHT 0 conversion r54 s158 STOICHIOMETRY
type: Stoichiometry
physical entity: s158
stoichiometric coefficient: 1.0

r25
type: Transport
participant stoichiometry: LEFT 0 conversion r25 s160 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion r25 s161 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion r25 s69 STOICHIOMETRY
right: s69
right: s161
left: s160

s75
type: PhysicalEntity
member physical entity: Hedgehog target gene
cellular location: nucleus

Hedgehog target gene
type: PhysicalEntity
xref: GO:0007228

LEFT 0 conversion r53 s70 STOICHIOMETRY
type: Stoichiometry
physical entity: s70
stoichiometric coefficient: 1.0

s1
type: PhysicalEntity
member physical entity: Patched
cellular location: Receiving cell

LEFT 0 conversion r55 s158 STOICHIOMETRY
type: Stoichiometry
physical entity: s158
stoichiometric coefficient: 1.0

LEFT 1 conversion r7 s1 STOICHIOMETRY
type: Stoichiometry
physical entity: s1
stoichiometric coefficient: 1.0

Q15465
type: UnificationXref
id: Q15465
db: UniProt Knowledgebase

s158
type: PhysicalEntity
member physical entity: Complex_br_(CBP/Cubitus)
cellular location: nucleus

RIGHT 0 conversion r14 s46 STOICHIOMETRY
type: Stoichiometry
physical entity: s46
stoichiometric coefficient: 1.0

RIGHT 0 conversion r7 s21 STOICHIOMETRY
type: Stoichiometry
physical entity: s21
stoichiometric coefficient: 1.0

s70
type: PhysicalEntity
member physical entity: Cubitus_space_interruptus
cellular location: nucleus

LEFT 0 conversion r15 s46 STOICHIOMETRY
type: Stoichiometry
physical entity: s46
stoichiometric coefficient: 1.0

s21
type: PhysicalEntity
member physical entity: Complex_br_(Patched/Hedgehog)
cellular location: Receiving cell

Sivakumar2011 HedgehogSignalingPathway
type: Pathway
pathway component: r51
pathway component: r53
pathway component: r52
pathway component: r55
pathway component: r54
pathway component: re24
pathway component: r23
pathway component: r15
pathway component: r26
pathway component: r14
pathway component: r25
pathway component: r7
xref: http://identifiers.org/pubmed/21978399
xref: CL:0000047
xref: BIOMD0000000395
xref: MODEL1101270001
xref: GO:0007224
xref: P00025
organism: biosource 1
comment: This BioPAX Level3 file was automatically generated on 23-Jun-2017 by SBML2BioPAX-3.1, BioModels.net, EMBL-EBI.
comment: The original model, 'Sivakumar2011_HedgehogSignalingPathway', was published in BioModels Database (http://www.ebi.ac.uk/biomodels/).
data source: BioModels Database

s9
type: PhysicalEntity
member physical entity: ATP
cellular location: Receiving cell

s69
type: PhysicalEntity
member physical entity: Complex_br_(Costal2/Fused/_br_Smoothened)
cellular location: lipid raft

s148
type: PhysicalEntity
member physical entity: smoothened
cellular location: Receiving cell

s159
type: PhysicalEntity
member physical entity: Complex_br_(Costal2/Fused/../microtubule)
cellular location: lipid raft

r7
type: Transport
participant stoichiometry: RIGHT 0 conversion r7 s21 STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion r7 s1 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion r7 s7 STOICHIOMETRY
right: s21
left: s7
left: s1

s10
type: PhysicalEntity
member physical entity: ADP
cellular location: Receiving cell

Complex_br_(Cubitus_space_interruptus_space_repressor/Su(fu))
type: PhysicalEntity
xref: GO:0043234

ADP
type: SmallMolecule
xref: CHEBI:16761

CHEBI:15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

s140
type: PhysicalEntity
member physical entity: Complex_br_(Sap18/Su(fu)/_br_Cubitus_space_interruptus_space_repressor)
cellular location: nucleus

LEFT 0 conversion r7 s7 STOICHIOMETRY
type: Stoichiometry
physical entity: s7
stoichiometric coefficient: 1.0

BioModels Database
type: Provenance
xref: BIOMD0000000395

http://identifiers.org/pubmed/21978399
type: PublicationXref
id: 21978399
db: PubMed

s46
type: PhysicalEntity
member physical entity: Complex_br_(Costal2/Fused/_br_Smoothened)
cellular location: Receiving cell

s158
type: PhysicalEntity
member physical entity: Complex_br_(CBP/Cubitus)
cellular location: nucleus

s160
type: PhysicalEntity
member physical entity: Complex_br_(Su(fu)/Fused/../_br_Smoothened)
cellular location: lipid raft

r51
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion r51 s135 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion r51 s140 STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion r51 s128 STOICHIOMETRY
right: s140
left: s128
left: s135

r53
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion r53 s70 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion r53 s70 STOICHIOMETRY
right: s70
left: s70

s68
type: PhysicalEntity
member physical entity: Microtubule
cellular location: Receiving cell

r52
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion r52 s75 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion r52 s140 STOICHIOMETRY
right: s75
left: s140

r55
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion r55 s158 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion r55 s75 STOICHIOMETRY
right: s75
left: s158

r54
type: BiochemicalReaction
participant stoichiometry: LEFT 1 conversion r54 s71 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion r54 s70 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion r54 s158 STOICHIOMETRY
right: s158
left: s70
left: s71

s71
type: PhysicalEntity
member physical entity: CBP
cellular location: nucleus

BioModels Database
type: Provenance
xref: MODEL1101270001

GO:0005874
type: UnificationXref
id: GO:0005874
db: Gene Ontology

LEFT 1 conversion re24 s150 STOICHIOMETRY
type: Stoichiometry
physical entity: s150
stoichiometric coefficient: 1.0

s161
type: PhysicalEntity
member physical entity: Complex_br_(Su(fu)/Cubitus)
cellular location: Receiving cell

CL:0000047
type: UnificationXref
id: CL:0000047
db: Cell Type Ontology

Complex_br_(Patched/Hedgehog)
type: PhysicalEntity
xref: GO:0043234

s70
type: PhysicalEntity
member physical entity: Cubitus_space_interruptus
cellular location: nucleus

LEFT 0 conversion r54 s70 STOICHIOMETRY
type: Stoichiometry
physical entity: s70
stoichiometric coefficient: 1.0

LEFT 0 conversion r25 s160 STOICHIOMETRY
type: Stoichiometry
physical entity: s160
stoichiometric coefficient: 1.0

s46
type: PhysicalEntity
member physical entity: Complex_br_(Costal2/Fused/_br_Smoothened)
cellular location: Receiving cell

LEFT 1 conversion r51 s128 STOICHIOMETRY
type: Stoichiometry
physical entity: s128
stoichiometric coefficient: 1.0