GO:0097345
type: UnificationXref
id: GO:0097345
db: Gene Ontology

RIGHT 1 conversion reaction 15 DISC STOICHIOMETRY
type: Stoichiometry
physical entity: DISC
stoichiometric coefficient: 1.0

LEFT 0 conversion reaction 17 Bid STOICHIOMETRY
type: Stoichiometry
physical entity: Bid
stoichiometric coefficient: 1.0

p30
type: PhysicalEntity
member physical entity: p30
cellular location: cell

LEFT 0 conversion reaction 2 DISC STOICHIOMETRY
type: Stoichiometry
physical entity: DISC
stoichiometric coefficient: 1.0

LEFT 0 conversion reaction 19 PrER mGFP STOICHIOMETRY
type: Stoichiometry
physical entity: PrER_mGFP
stoichiometric coefficient: 1.0

RIGHT 0 conversion reaction 11 p43 STOICHIOMETRY
type: Stoichiometry
physical entity: p43
stoichiometric coefficient: 1.0

mCherry
type: Protein
xref: Q9U6Y8

DISCp55
type: PhysicalEntity
member physical entity: DISCp55
cellular location: cell

mCherry
type: PhysicalEntity
member physical entity: mCherry
cellular location: cell

RIGHT 0 conversion reaction 10 p43 STOICHIOMETRY
type: Stoichiometry
physical entity: p43
stoichiometric coefficient: 1.0

p18
type: PhysicalEntity
member physical entity: p18
cellular location: cell

DISCp55
type: PhysicalEntity
member physical entity: DISCp55
cellular location: cell

P25445
type: UnificationXref
id: P25445
db: UniProt Knowledgebase

SO:0001531
type: UnificationXref
id: SO:0001531

p30
type: PhysicalEntity
member physical entity: p30
cellular location: cell

RIGHT 1 conversion reaction 7 DISC STOICHIOMETRY
type: Stoichiometry
physical entity: DISC
stoichiometric coefficient: 1.0

p18
type: PhysicalEntity
member physical entity: p18
cellular location: cell

P42212
type: UnificationXref
id: P42212
db: UniProt Knowledgebase

PrER_mGFP
type: PhysicalEntity
member physical entity: PrER_mGFP
cellular location: cell

p43
type: PhysicalEntity
member physical entity: p43
cellular location: cell

FADD
type: Protein
xref: Q13158

p43
type: PhysicalEntity
member physical entity: p43
cellular location: cell

RIGHT 0 conversion reaction 9 p18 STOICHIOMETRY
type: Stoichiometry
physical entity: p18
stoichiometric coefficient: 1.0

BIOMD0000000525
type: UnificationXref
id: BIOMD0000000525
db: BioModels Database

PrER
type: Complex
xref: P27824
xref: CHEBI:50406

RIGHT 1 conversion reaction 18 mCherry STOICHIOMETRY
type: Stoichiometry
physical entity: mCherry
stoichiometric coefficient: 1.0

RIGHT 0 conversion reaction 12 p43 STOICHIOMETRY
type: Stoichiometry
physical entity: p43
stoichiometric coefficient: 1.0

GO:0031264
type: UnificationXref
id: GO:0031264
db: Gene Ontology

PrNES
type: Complex
xref: SO:0001531
xref: CHEBI:50406

RIGHT 1 conversion reaction 8 DISC STOICHIOMETRY
type: Stoichiometry
physical entity: DISC
stoichiometric coefficient: 1.0

PATO:0002355
type: UnificationXref
id: PATO:0002355

LEFT 0 conversion reaction 3 p55free STOICHIOMETRY
type: Stoichiometry
physical entity: p55free
stoichiometric coefficient: 1.0

p18inactive
type: Protein
xref: Q14790
xref: PATO:0002355

p18
type: Protein
xref: Q14790

LEFT 1 conversion reaction 3 DISC STOICHIOMETRY
type: Stoichiometry
physical entity: DISC
stoichiometric coefficient: 1.0

LEFT 0 conversion reaction 13 p30 STOICHIOMETRY
type: Stoichiometry
physical entity: p30
stoichiometric coefficient: 1.0

LEFT 0 conversion reaction 1 FADD STOICHIOMETRY
type: Stoichiometry
physical entity: FADD
stoichiometric coefficient: 1.0

MAMO_0000046
type: UnificationXref
id: MAMO_0000046
db: Mathematical Modelling Ontology

DISCp55
type: PhysicalEntity
member physical entity: DISCp55
cellular location: cell

PrER_mGFP
type: Complex
xref: P27824
xref: P42212
xref: CHEBI:50406

DISC
type: PhysicalEntity
member physical entity: DISC
cellular location: cell

P27824
type: UnificationXref
id: P27824
db: UniProt Knowledgebase

PrNES_mCherry
type: PhysicalEntity
member physical entity: PrNES_mCherry
cellular location: cell

RIGHT 0 conversion reaction 2 FADD STOICHIOMETRY
type: Stoichiometry
physical entity: FADD
stoichiometric coefficient: 1.0

tBid
type: PhysicalEntity
member physical entity: tBid
cellular location: cell

RIGHT 0 conversion reaction 7 p18 STOICHIOMETRY
type: Stoichiometry
physical entity: p18
stoichiometric coefficient: 1.0

LEFT 0 conversion reaction 16 p18 STOICHIOMETRY
type: Stoichiometry
physical entity: p18
stoichiometric coefficient: 1.0

LEFT 0 conversion reaction 6 DISCp55 STOICHIOMETRY
type: Stoichiometry
physical entity: DISCp55
stoichiometric coefficient: 1.0

BTO:0000567
type: UnificationXref
id: BTO:0000567
db: Brenda Tissue Ontology

http://identifiers.org/pubmed/24619646
type: PublicationXref
id: 24619646
db: PubMed

p30
type: Dna
xref: ENSG00000064012

GO:0005623
type: UnificationXref
id: GO:0005623
db: Gene Ontology

MODEL1403050002
type: Pathway
pathway component: reaction_6
pathway component: reaction_5
pathway component: reaction_8
pathway component: reaction_7
pathway component: reaction_9
pathway component: reaction_17
pathway component: reaction_16
pathway component: reaction_15
pathway component: reaction_14
pathway component: reaction_2
pathway component: reaction_1
pathway component: reaction_4
pathway component: reaction_19
pathway component: reaction_3
pathway component: reaction_18
pathway component: reaction_13
pathway component: reaction_12
pathway component: reaction_11
pathway component: reaction_10
xref: GO:0006915
xref: MODEL1403050002
xref: BTO:0000567
xref: BIOMD0000000525
xref: http://identifiers.org/pubmed/24619646
xref: MAMO_0000046
organism: biosource 1
comment: This BioPAX Level3 file was automatically generated on 23-Jun-2017 by SBML2BioPAX-3.1, BioModels.net, EMBL-EBI.
comment: The original model, 'MODEL1403050002', was published in BioModels Database (http://www.ebi.ac.uk/biomodels/).
data source: BioModels Database

PrNES
type: PhysicalEntity
member physical entity: PrNES
cellular location: cell

P55957
type: UnificationXref
id: P55957
db: UniProt Knowledgebase

p43
type: PhysicalEntity
member physical entity: p43
cellular location: cell

DISC
type: PhysicalEntity
member physical entity: DISC
cellular location: cell

p18
type: PhysicalEntity
member physical entity: p18
cellular location: cell

DISC
type: PhysicalEntity
member physical entity: DISC
cellular location: cell

ENSG00000064012
type: UnificationXref
id: ENSG00000064012
db: Ensembl

FADD
type: PhysicalEntity
member physical entity: FADD
cellular location: cell

Bid
type: Protein
xref: P55957

LEFT 0 conversion reaction 10 DISCp55 STOICHIOMETRY
type: Stoichiometry
physical entity: DISCp55
stoichiometric coefficient: 1.0

DISCp55
type: PhysicalEntity
member physical entity: DISCp55
cellular location: cell

p43
type: Protein
xref: O15519

RIGHT 0 conversion reaction 15 p18 STOICHIOMETRY
type: Stoichiometry
physical entity: p18
stoichiometric coefficient: 1.0

DISC
type: PhysicalEntity
member physical entity: DISC
cellular location: cell

LEFT 0 conversion reaction 7 p43 STOICHIOMETRY
type: Stoichiometry
physical entity: p43
stoichiometric coefficient: 1.0

Bid
type: PhysicalEntity
member physical entity: Bid
cellular location: cell

O15519
type: UnificationXref
id: O15519
db: UniProt Knowledgebase

RIGHT 0 conversion reaction 6 p30 STOICHIOMETRY
type: Stoichiometry
physical entity: p30
stoichiometric coefficient: 1.0

reaction_6
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion reaction 6 DISCp55 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 6 p30 STOICHIOMETRY
right: p30
spontaneous: true
left: DISCp55
conversion direction: RIGHT_TO_LEFT

p18
type: PhysicalEntity
member physical entity: p18
cellular location: cell

reaction_5
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion reaction 5 DISCp55 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 5 p30 STOICHIOMETRY
right: p30
spontaneous: true
left: DISCp55
conversion direction: RIGHT_TO_LEFT

p43
type: PhysicalEntity
member physical entity: p43
cellular location: cell

CD95
type: Protein
xref: P25445

reaction_8
type: BiochemicalReaction
participant stoichiometry: RIGHT 1 conversion reaction 8 DISC STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion reaction 8 p43 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 8 p18 STOICHIOMETRY
right: p18
right: DISC
left: p43

reaction_7
type: BiochemicalReaction
participant stoichiometry: RIGHT 1 conversion reaction 7 DISC STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 7 p18 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion reaction 7 p43 STOICHIOMETRY
right: p18
right: DISC
left: p43

reaction_9
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion reaction 9 p43 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion reaction 9 DISC STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 9 p18 STOICHIOMETRY
right: p18
right: DISC
left: p43

reaction_2
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion reaction 2 DISC STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 2 FADD STOICHIOMETRY
right: FADD
left: DISC

RIGHT 0 conversion reaction 16 p18inactive STOICHIOMETRY
type: Stoichiometry
physical entity: p18inactive
stoichiometric coefficient: 1.0

reaction_1
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion reaction 1 DISC STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion reaction 1 FADD STOICHIOMETRY
right: DISC
left: FADD

reaction_4
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion reaction 4 DISCp55 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 4 p30 STOICHIOMETRY
right: p30
spontaneous: true
left: DISCp55
conversion direction: RIGHT_TO_LEFT

reaction_3
type: ComplexAssembly
participant stoichiometry: LEFT 1 conversion reaction 3 DISC STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion reaction 3 p55free STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 3 DISCp55 STOICHIOMETRY
right: DISCp55
spontaneous: true
left: DISC
left: p55free
conversion direction: LEFT_TO_RIGHT

DISCp55
type: Complex
xref: GO:0031264
xref: ENSG00000064012

RIGHT 1 conversion reaction 9 DISC STOICHIOMETRY
type: Stoichiometry
physical entity: DISC
stoichiometric coefficient: 1.0

p55free
type: Dna
xref: ENSG00000064012

RIGHT 0 conversion reaction 17 tBid STOICHIOMETRY
type: Stoichiometry
physical entity: tBid
stoichiometric coefficient: 1.0

p18inactive
type: PhysicalEntity
member physical entity: p18inactive
cellular location: cell

GO:0006915
type: UnificationXref
id: GO:0006915
db: Gene Ontology

p18
type: PhysicalEntity
member physical entity: p18
cellular location: cell

RIGHT 1 conversion reaction 14 DISC STOICHIOMETRY
type: Stoichiometry
physical entity: DISC
stoichiometric coefficient: 1.0

RIGHT 0 conversion reaction 19 PrER STOICHIOMETRY
type: Stoichiometry
physical entity: PrER
stoichiometric coefficient: 1.0

p18
type: PhysicalEntity
member physical entity: p18
cellular location: cell

LEFT 0 conversion reaction 8 p43 STOICHIOMETRY
type: Stoichiometry
physical entity: p43
stoichiometric coefficient: 1.0

cell
type: CellularLocationVocabulary
xref: GO:0005623

LEFT 0 conversion reaction 11 DISCp55 STOICHIOMETRY
type: Stoichiometry
physical entity: DISCp55
stoichiometric coefficient: 1.0

RIGHT 0 conversion reaction 14 p18 STOICHIOMETRY
type: Stoichiometry
physical entity: p18
stoichiometric coefficient: 1.0

p30
type: PhysicalEntity
member physical entity: p30
cellular location: cell

Q14790
type: UnificationXref
id: Q14790
db: UniProt Knowledgebase

CD95L
type: Protein
xref: P48023

p43
type: PhysicalEntity
member physical entity: p43
cellular location: cell

DISCp55
type: PhysicalEntity
member physical entity: DISCp55
cellular location: cell

LEFT 0 conversion reaction 15 p30 STOICHIOMETRY
type: Stoichiometry
physical entity: p30
stoichiometric coefficient: 1.0

p30
type: PhysicalEntity
member physical entity: p30
cellular location: cell

Q9U6Y8
type: UnificationXref
id: Q9U6Y8
db: UniProt Knowledgebase

mGFP
type: PhysicalEntity
member physical entity: mGFP
cellular location: cell

DISC
type: PhysicalEntity
member physical entity: DISC
cellular location: cell

RIGHT 0 conversion reaction 4 p30 STOICHIOMETRY
type: Stoichiometry
physical entity: p30
stoichiometric coefficient: 1.0

RIGHT 0 conversion reaction 18 PrNES STOICHIOMETRY
type: Stoichiometry
physical entity: PrNES
stoichiometric coefficient: 1.0

LEFT 0 conversion reaction 14 p30 STOICHIOMETRY
type: Stoichiometry
physical entity: p30
stoichiometric coefficient: 1.0

reaction_17
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion reaction 17 Bid STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 17 tBid STOICHIOMETRY
right: tBid
spontaneous: true
left: Bid
conversion direction: LEFT_TO_RIGHT

Q13158
type: UnificationXref
id: Q13158
db: UniProt Knowledgebase

reaction_16
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion reaction 16 p18 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 16 p18inactive STOICHIOMETRY
right: p18inactive
left: p18

reaction_15
type: BiochemicalReaction
participant stoichiometry: RIGHT 1 conversion reaction 15 DISC STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 15 p18 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion reaction 15 p30 STOICHIOMETRY
right: p18
right: DISC
left: p30

reaction_14
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion reaction 14 p30 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion reaction 14 DISC STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 14 p18 STOICHIOMETRY
right: p18
right: DISC
left: p30

reaction_19
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion reaction 19 PrER STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion reaction 19 PrER mGFP STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion reaction 19 mGFP STOICHIOMETRY
right: mGFP
right: PrER
left: PrER_mGFP

RIGHT 0 conversion reaction 3 DISCp55 STOICHIOMETRY
type: Stoichiometry
physical entity: DISCp55
stoichiometric coefficient: 1.0

reaction_18
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion reaction 18 PrNES STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion reaction 18 PrNES mCherry STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion reaction 18 mCherry STOICHIOMETRY
right: PrNES
right: mCherry
left: PrNES_mCherry

reaction_13
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion reaction 13 p30 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion reaction 13 DISC STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 13 p18 STOICHIOMETRY
right: p18
right: DISC
left: p30

http://identifiers.org/taxonomy/9606
type: UnificationXref
id: 9606
db: Taxonomy

reaction_12
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion reaction 12 DISCp55 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 12 p43 STOICHIOMETRY
right: p43
spontaneous: true
left: DISCp55
conversion direction: RIGHT_TO_LEFT

reaction_11
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion reaction 11 DISCp55 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 11 p43 STOICHIOMETRY
right: p43
spontaneous: true
left: DISCp55
conversion direction: RIGHT_TO_LEFT

LEFT 0 conversion reaction 18 PrNES mCherry STOICHIOMETRY
type: Stoichiometry
physical entity: PrNES_mCherry
stoichiometric coefficient: 1.0

reaction_10
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion reaction 10 DISCp55 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion reaction 10 p43 STOICHIOMETRY
right: p43
spontaneous: true
left: DISCp55
conversion direction: RIGHT_TO_LEFT

RIGHT 1 conversion reaction 13 DISC STOICHIOMETRY
type: Stoichiometry
physical entity: DISC
stoichiometric coefficient: 1.0

DISC
type: PhysicalEntity
member physical entity: DISC
cellular location: cell

LEFT 0 conversion reaction 4 DISCp55 STOICHIOMETRY
type: Stoichiometry
physical entity: DISCp55
stoichiometric coefficient: 1.0

DISCp55
type: PhysicalEntity
member physical entity: DISCp55
cellular location: cell

PrER
type: PhysicalEntity
member physical entity: PrER
cellular location: cell

RIGHT 0 conversion reaction 1 DISC STOICHIOMETRY
type: Stoichiometry
physical entity: DISC
stoichiometric coefficient: 1.0

DISC
type: PhysicalEntity
member physical entity: DISC
cellular location: cell

DISC
type: PhysicalEntity
member physical entity: DISC
cellular location: cell

p30
type: PhysicalEntity
member physical entity: p30
cellular location: cell

RIGHT 0 conversion reaction 8 p18 STOICHIOMETRY
type: Stoichiometry
physical entity: p18
stoichiometric coefficient: 1.0

LEFT 0 conversion reaction 5 DISCp55 STOICHIOMETRY
type: Stoichiometry
physical entity: DISCp55
stoichiometric coefficient: 1.0

FADD
type: PhysicalEntity
member physical entity: FADD
cellular location: cell

DISC
type: PhysicalEntity
xref: GO:0031264

p18
type: PhysicalEntity
member physical entity: p18
cellular location: cell

MODEL1403050002
type: UnificationXref
id: MODEL1403050002
db: BioModels Database

CHEBI:50406
type: UnificationXref
id: CHEBI:50406
db: ChEBI

p55free
type: PhysicalEntity
member physical entity: p55free
cellular location: cell

P48023
type: UnificationXref
id: P48023
db: UniProt Knowledgebase

LEFT 0 conversion reaction 12 DISCp55 STOICHIOMETRY
type: Stoichiometry
physical entity: DISCp55
stoichiometric coefficient: 1.0

PrNES_mCherry
type: Complex
xref: Q9U6Y8
xref: SO:0001531
xref: CHEBI:50406

RIGHT 0 conversion reaction 13 p18 STOICHIOMETRY
type: Stoichiometry
physical entity: p18
stoichiometric coefficient: 1.0

LEFT 0 conversion reaction 9 p43 STOICHIOMETRY
type: Stoichiometry
physical entity: p43
stoichiometric coefficient: 1.0

tBid
type: Complex
xref: GO:0097345
xref: P55957

BioModels Database
type: Provenance
xref: BIOMD0000000525

DISCp55
type: PhysicalEntity
member physical entity: DISCp55
cellular location: cell

p30
type: PhysicalEntity
member physical entity: p30
cellular location: cell

RIGHT 1 conversion reaction 19 mGFP STOICHIOMETRY
type: Stoichiometry
physical entity: mGFP
stoichiometric coefficient: 1.0

RIGHT 0 conversion reaction 5 p30 STOICHIOMETRY
type: Stoichiometry
physical entity: p30
stoichiometric coefficient: 1.0

p43
type: PhysicalEntity
member physical entity: p43
cellular location: cell

BioModels Database
type: Provenance
xref: MODEL1403050002

mGFP
type: Protein
xref: P42212

DISC
type: PhysicalEntity
member physical entity: DISC
cellular location: cell