APAP
type: SmallMolecule
xref: CHEBI:46195

APAPconj_Sul
type: PhysicalEntity
member physical entity: APAPconj_Sul
cellular location: Hepatocyte

FMA:14515
type: UnificationXref
id: FMA:14515
db: FMA

LEFT 0 conversion J1 GSH STOICHIOMETRY
type: Stoichiometry
physical entity: GSH
stoichiometric coefficient: 1.0

APAPconj_Sul
type: SmallMolecule
xref: CHEBI:32635

LEFT 0 conversion J2 X1 STOICHIOMETRY
type: Stoichiometry
physical entity: X1
stoichiometric coefficient: 1.0

PW:0000375
type: UnificationXref
id: PW:0000375
db: Pathway Ontology

RIGHT 0 conversion J0 NAPQI STOICHIOMETRY
type: Stoichiometry
physical entity: NAPQI
stoichiometric coefficient: 1.0

http://identifiers.org/taxonomy/9606
type: UnificationXref
id: 9606
db: Taxonomy

NAPQIGSH
type: PhysicalEntity
member physical entity: NAPQIGSH
cellular location: Hepatocyte

Hepatocyte
type: CellularLocationVocabulary
xref: FMA:14515
xref: FMA:68646
xref: BTO:0000575

CHEBI:16856
type: UnificationXref
id: CHEBI:16856
db: ChEBI

BIOMD0000000624
type: UnificationXref
id: BIOMD0000000624
db: BioModels Database

http://identifiers.org/efo/0004228
type: UnificationXref
id: 0004228
db: Experimental Factor Ontology

MAMO_0000046
type: UnificationXref
id: MAMO_0000046
db: Mathematical Modelling Ontology

RIGHT 0 conversion J1 NAPQIGSH STOICHIOMETRY
type: Stoichiometry
physical entity: NAPQIGSH
stoichiometric coefficient: 1.0

LEFT 0 conversion J3 APAP STOICHIOMETRY
type: Stoichiometry
physical entity: APAP
stoichiometric coefficient: 1.0

CHEBI:46195
type: UnificationXref
id: CHEBI:46195
db: ChEBI

http://identifiers.org/pubmed/19219744
type: UnificationXref
id: 19219744
db: PubMed

RIGHT 0 conversion J2 GSH STOICHIOMETRY
type: Stoichiometry
physical entity: GSH
stoichiometric coefficient: 1.0

GO:0004363
type: UnificationXref
id: GO:0004363
db: Gene Ontology

FMA:68646
type: UnificationXref
id: FMA:68646
db: FMA

X1
type: PhysicalEntity
member physical entity: X1
cellular location: Hepatocyte

APAPconj_Glu
type: SmallMolecule
xref: CHEBI:32636

GSH
type: PhysicalEntity
member physical entity: GSH
cellular location: Hepatocyte

http://identifiers.org/pubmed/27636091
type: PublicationXref
id: 27636091
db: PubMed

GO:0071704
type: UnificationXref
id: GO:0071704
db: Gene Ontology

NAPQI
type: SmallMolecule
xref: CHEBI:29132

CHEBI:32639
type: UnificationXref
id: CHEBI:32639
db: ChEBI

CHEBI:32635
type: UnificationXref
id: CHEBI:32635
db: ChEBI

APAP
type: PhysicalEntity
member physical entity: APAP
cellular location: Hepatocyte

GO:0051923
type: UnificationXref
id: GO:0051923
db: Gene Ontology

CHEBI:32636
type: UnificationXref
id: CHEBI:32636
db: ChEBI

GO:0044237
type: UnificationXref
id: GO:0044237
db: Gene Ontology

NAPQI
type: PhysicalEntity
member physical entity: NAPQI
cellular location: Hepatocyte

NAPQIGSH
type: SmallMolecule
xref: CHEBI:32639

MODEL1509230011
type: UnificationXref
id: MODEL1509230011
db: BioModels Database

GO:0042739
type: UnificationXref
id: GO:0042739
db: Gene Ontology

X1
type: PhysicalEntity

LEFT 0 conversion J0 APAP STOICHIOMETRY
type: Stoichiometry
physical entity: APAP
stoichiometric coefficient: 1.0

RIGHT 0 conversion J3 APAPconj Glu STOICHIOMETRY
type: Stoichiometry
physical entity: APAPconj_Glu
stoichiometric coefficient: 1.0

GO:0052697
type: UnificationXref
id: GO:0052697
db: Gene Ontology

http://identifiers.org/pubmed/6424115
type: UnificationXref
id: 6424115
db: PubMed

GSH
type: SmallMolecule
xref: CHEBI:16856

GSH
type: PhysicalEntity
member physical entity: GSH
cellular location: Hepatocyte

LEFT 0 conversion J4 APAP STOICHIOMETRY
type: Stoichiometry
physical entity: APAP
stoichiometric coefficient: 1.0

BioModels Database
type: Provenance
xref: BIOMD0000000624

GO:0045333
type: UnificationXref
id: GO:0045333
db: Gene Ontology

MODEL1509230011
type: Pathway
pathway component: J1
pathway component: J2
pathway component: J3
pathway component: J4
pathway component: J0
xref: MODEL1509230011
xref: GO:0042739
xref: http://identifiers.org/pubmed/27636091
xref: BIOMD0000000624
xref: http://identifiers.org/efo/0004228
xref: MAMO_0000046
organism: biosource 1
comment: The original model, 'MODEL1509230011', was published in BioModels Database (http://www.ebi.ac.uk/biomodels/).
comment: This BioPAX Level3 file was automatically generated on Apr 8, 2022 by SBML2BioPAX-3.1, BioModels.net, EMBL-EBI.
data source: BioModels Database

APAP
type: PhysicalEntity
member physical entity: APAP
cellular location: Hepatocyte

LEFT 1 conversion J1 NAPQI STOICHIOMETRY
type: Stoichiometry
physical entity: NAPQI
stoichiometric coefficient: 1.0

NAPQI
type: PhysicalEntity
member physical entity: NAPQI
cellular location: Hepatocyte

BTO:0000575
type: UnificationXref
id: BTO:0000575
db: Brenda Tissue Ontology

APAP
type: PhysicalEntity
member physical entity: APAP
cellular location: Hepatocyte

BioModels Database
type: Provenance
xref: MODEL1509230011

J0
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion J0 APAP STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion J0 NAPQI STOICHIOMETRY
xref: GO:0045333
xref: http://identifiers.org/pubmed/19219744
xref: GO:0044237
xref: GO:0071704
xref: http://identifiers.org/pubmed/6424115
xref: PW:0000375
right: NAPQI
left: APAP

J1
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion J1 GSH STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion J1 NAPQI STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion J1 NAPQIGSH STOICHIOMETRY
right: NAPQIGSH
left: NAPQI
left: GSH

J2
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion J2 GSH STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion J2 X1 STOICHIOMETRY
xref: GO:0004363
right: GSH
left: X1

J3
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion J3 APAPconj Glu STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion J3 APAP STOICHIOMETRY
xref: GO:0052697
right: APAPconj_Glu
left: APAP

RIGHT 0 conversion J4 APAPconj Sul STOICHIOMETRY
type: Stoichiometry
physical entity: APAPconj_Sul
stoichiometric coefficient: 1.0

J4
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion J4 APAPconj Sul STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion J4 APAP STOICHIOMETRY
xref: GO:0051923
right: APAPconj_Sul
left: APAP

APAPconj_Glu
type: PhysicalEntity
member physical entity: APAPconj_Glu
cellular location: Hepatocyte

CHEBI:29132
type: UnificationXref
id: CHEBI:29132
db: ChEBI