This is a reinvestigation of a previous model depicting cancer remission. It involves application of mathematical tools from control theory to assess the optimal approach during the use of Adaptive Cellular Immunotherapy and interleukin-2 treatment.
 Meyer Johannes johannes.p.meyer@gmail.com EMBL-EBI 2019-08-01T13:57:16Z 2019-08-01T13:57:16Z 2019-08-01T13:57:16Z johannes.p.meyer@gmail.com Meyer Johannes EMBL-EBI 2019-08-01T14:10:10Z r_1 M k_1 r_1 M 1 M k_1 2019-08-01T14:13:52Z alpha_1 M N alpha_1 M N 2019-08-01T14:48:13Z mu_2 N Z mu_2 N Z 2019-08-01T14:39:31Z mu_2 N Z mu_2 N Z 2019-08-01T14:40:54Z alpha_2 M N alpha_2 M N 2019-08-01T15:00:58Z 2019-08-01T14:12:04Z 2019-08-01T14:50:01Z 2019-08-01T14:50:45Z 2019-08-01T14:52:59Z 2019-08-01T16:43:32Z 2019-08-01T14:04:24Z compartment Function_for_Tumor_Growth r_1 M_Tumor_Cells k_1 2019-08-01T14:13:31Z compartment Function_for_Tumor_Killing_T_Cells alpha_1 M_Tumor_Cells N_CTL 2019-08-01T14:39:14Z compartment Function_for_CTL_Recruitment mu_2 N_CTL Z_THL 2019-08-01T14:39:57Z compartment d_1 N_CTL 2019-08-01T14:40:34Z compartment Function_for_CTL_Decay alpha_2 M_Tumor_Cells N_CTL 2019-08-01T14:43:08Z compartment Function_for_Tumor_Growth r_2 Z_THL k_2 2019-08-01T14:44:15Z compartment Function_for_THL_Decay_IL_2 mu_2 N_CTL Z_THL 2019-08-01T16:40:11Z compartment mu_1 M_Tumor_Cells