This is an ordinary differential equation-based mathematical model describing the inflammatory phase of the wound healing response. The model describes the interactions in the wound between wound debris, pathogens, neutrophils and macrophages, as well as the modulation of these interactions by estrogen and cortisol.

Meyer Johannes johannes.p.meyer@gmail.com EMBL-EBI 2019-11-13T12:02:59Z 2019-11-13T12:02:59Z 2019-11-13T12:02:59Z johannes.p.meyer@gmail.com Meyer Johannes EMBL-EBI 2019-11-13T12:55:12Z

v v

2019-11-13T12:33:55Z

kpg P pinf kpg P 1 P pinf

2019-11-13T12:36:15Z

kpn P N ken E kpn P N 1 ken E

2019-11-13T12:35:06Z

kpb sb P mub kbp kpb sb P mub kbp P

2019-11-13T12:51:03Z

smr R1 mumr smr R1 mumr R1

2019-11-13T12:39:47Z

kptm Pt fi2 kem E kptm Pt fi2 1 kem E

2019-11-13T12:38:55Z

kptn Pt N ken kptn Pt N 1 ken N

2019-11-13T12:37:02Z

kpm P fi2 kem E kpm P fi2 1 kem E

2019-11-13T12:55:13Z

knm N fi2 knm N fi2

2019-11-13T13:40:29Z 2019-11-13T13:45:16Z 2019-11-13T13:45:28Z 2019-11-13T13:44:29Z 2019-11-13T13:44:58Z 2019-11-13T13:27:12Z 2019-11-13T13:27:11Z 2019-11-13T13:27:18Z 2019-11-13T13:27:12Z 2019-11-13T13:27:12Z 2019-11-13T13:27:15Z 2019-11-13T13:27:09Z 2019-11-13T13:27:10Z 2019-11-13T13:27:31Z 2019-11-13T13:27:14Z 2019-11-13T12:54:04Z 2019-11-13T13:27:08Z 2019-11-13T13:27:07Z 2019-11-13T13:27:06Z 2019-11-13T13:27:06Z 2019-11-13T13:27:07Z 2019-11-13T13:27:30Z 2019-11-13T13:22:01Z 2019-11-13T13:21:54Z 2019-11-13T12:13:50Z 2019-11-13T12:26:36Z 2019-11-13T12:20:34Z 2019-11-13T12:23:03Z 2019-11-13T13:24:45Z 2019-11-13T13:27:06Z 2019-11-13T13:24:44Z 2019-11-13T13:27:05Z 2019-11-13T13:00:16Z 2019-11-13T13:00:39Z 2019-11-13T13:24:43Z 2019-11-13T13:27:11Z 2019-11-13T13:27:18Z 2019-11-13T12:24:54Z 2019-11-13T13:27:28Z 2019-11-13T13:27:13Z 2019-11-13T13:27:11Z 2019-11-13T12:56:17Z 2019-11-13T12:57:45Z 2019-11-13T12:18:46Z

kmm 1 E EMinf 2

M 1 N Ninf 2 C Cm1 2

kmpt Pt kmp P fEM_Kmm_E M kmn N 1 C Cm2 2

knpt Pt knp P 1 C Cn 2

snr R2 munr R2 1 E ENinf 2

2019-11-13T12:33:41Z

compartment Function_for_Pathogen_Growth kpg P pinf

2019-11-13T12:34:46Z

compartment Function_for_Pathogen_Destruction_Background_Response kpb sb P mub kbp

2019-11-13T12:35:54Z

compartment Function_for_Pathogen_Destruction_Neutrophils kpn P N ken E

2019-11-13T12:36:53Z

compartment Function_for_Pathogen_Destruction_Macrophages kpm P fi2 kem E

2019-11-13T12:38:39Z

compartment Function_for_Debris_Destruction_Neutrophils kptn Pt N ken

2019-11-13T12:39:36Z

compartment Function_for_Debris_Destruction_Macrophages kptm Pt fi2 kem E

2019-11-13T12:40:33Z

compartment mun N

2019-11-13T12:41:03Z

compartment mupt Pt

2019-11-13T12:50:47Z

compartment Function_for_Macrophage_Recruitment smr R1 mumr

2019-11-13T12:51:58Z

compartment mum M

2019-11-13T12:52:44Z

compartment Constant_flux__irreversible fEN

2019-11-13T12:54:54Z

compartment Function_for_Neutrophil_Destruction_Macrophage knm N fi2