C19618
type: unificationXref
ID: C19618

conversion STATP2n Dephosphorylation
type: complexAssembly
XREF: C20612
LEFT: LEFT 0 conversion STATP2n Dephosphorylation STATP2n
SPONTANEOUS: R_L

C20493
type: unificationXref
ID: C20493
DB: NCIt

RIGHT 0 conversion STAT mRNA Induction STATm
type: physicalEntityParticipant
PHYSICAL-ENTITY: STATm
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

C20495
type: unificationXref
ID: C20495

C20494
type: unificationXref
ID: C20494

conversion STATP2n Formation
type: complexAssembly
XREF: C97201
SPONTANEOUS: L_R
RIGHT: RIGHT 0 conversion STATP2n Formation STATP2n

RIGHT 0 conversion IRF7 Translation IRF7Pn
type: physicalEntityParticipant
PHYSICAL-ENTITY: IRF7Pn
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

C18011
type: unificationXref
ID: C18011
DB: NCIt

http://identifiers.org/taxonomy/9606
type: unificationXref
ID: 9606
DB: Taxonomy

LEFT 0 conversion IFNb mRNA Degradation IFNBm
type: physicalEntityParticipant
PHYSICAL-ENTITY: IFNBm
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion IFNa mRNA Induction IFNam
type: physicalEntityParticipant
PHYSICAL-ENTITY: IFNam
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion STAT mRNA Degradation STATm
type: physicalEntityParticipant
PHYSICAL-ENTITY: STATm
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

compartment
type: openControlledVocabulary
XREF: C13356
TERM: compartment

LEFT 0 conversion IRF7 mRNA Degradation IRF7m
type: physicalEntityParticipant
PHYSICAL-ENTITY: IRF7m
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion IRF7 mRNA Induction IRF7m
type: physicalEntityParticipant
PHYSICAL-ENTITY: IRF7m
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

MAMO_0000046
type: unificationXref
ID: MAMO_0000046
DB: Mathematical Modelling Ontology

LEFT 0 conversion SOCS mRNA Degradation SOCSm
type: physicalEntityParticipant
PHYSICAL-ENTITY: SOCSm
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion IFNb mRNA Induction IFNBm
type: physicalEntityParticipant
PHYSICAL-ENTITY: IFNBm
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion STAT Translation STAT
type: physicalEntityParticipant
PHYSICAL-ENTITY: STAT
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

Fribourg2014 Model of influenza A virus infection dynamics of viral antagonism and innate immune response
type: pathway
XREF: C20493
XREF: BIOMD0000000889
XREF: MODEL1912120001
XREF: PR:000044797
XREF: C18011
XREF: http://identifiers.org/pubmed/24594370
XREF: MAMO_0000046
PATHWAY-COMPONENTS: conversion IFNb mRNA Induction
PATHWAY-COMPONENTS: conversion STATP2n Dephosphorylation
PATHWAY-COMPONENTS: conversion STAT Degradation
PATHWAY-COMPONENTS: conversion IFNaenv Translation Secretion
PATHWAY-COMPONENTS: conversion TNFa mRNA Induction
PATHWAY-COMPONENTS: conversion TNFa Translation Secretion
PATHWAY-COMPONENTS: conversion IRF7 mRNA Degradation
PATHWAY-COMPONENTS: conversion SOCS mRNA Induction
PATHWAY-COMPONENTS: conversion IRF7 Translation
PATHWAY-COMPONENTS: conversion IFNb mRNA Degradation
PATHWAY-COMPONENTS: conversion IRF7 mRNA Induction
PATHWAY-COMPONENTS: conversion TNFa mRNA Degradation
PATHWAY-COMPONENTS: conversion STATP2n Formation
PATHWAY-COMPONENTS: conversion IFNBenv Translation Secretion
PATHWAY-COMPONENTS: conversion STAT Translation
PATHWAY-COMPONENTS: conversion IFNa mRNA Induction
PATHWAY-COMPONENTS: conversion STAT mRNA Induction
PATHWAY-COMPONENTS: conversion SOCS mRNA Degradation
PATHWAY-COMPONENTS: conversion IFNa mRNA Degradation
PATHWAY-COMPONENTS: conversion STAT mRNA Degradation
COMMENT: The original model, 'Fribourg2014___Model_of_influenza_A_virus_infection_dynamics_of_viral_antagonism_and_innate_immune_response', was published in BioModels Database (http://www.ebi.ac.uk/biomodels/).
COMMENT: This BioPAX Level2 file was automatically generated on Apr 8, 2022 by SBML2BioPAX-3.1, BioModels.net, EMBL-EBI.
ORGANISM: biosource 1
DATA-SOURCE: datasource 2
DATA-SOURCE: datasource 1

RIGHT 0 conversion IFNBenv Translation Secretion IFNBenv
type: physicalEntityParticipant
PHYSICAL-ENTITY: IFNBenv
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

C97796
type: unificationXref
ID: C97796

LEFT 0 conversion IFNa mRNA Degradation IFNam
type: physicalEntityParticipant
PHYSICAL-ENTITY: IFNam
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

C13356
type: unificationXref
ID: C13356
DB: NCIt

LEFT 0 conversion STATP2n Dephosphorylation STATP2n
type: physicalEntityParticipant
PHYSICAL-ENTITY: STATP2n
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion SOCS mRNA Induction SOCSm
type: physicalEntityParticipant
PHYSICAL-ENTITY: SOCSm
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion TNFa Translation Secretion TFNenv
type: physicalEntityParticipant
PHYSICAL-ENTITY: TFNenv
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

MODEL1912120001
type: unificationXref
ID: MODEL1912120001
DB: BioModels Database

C97201
type: unificationXref
ID: C97201
DB: NCIt

BIOMD0000000889
type: unificationXref
ID: BIOMD0000000889
DB: BioModels Database

LEFT 0 conversion TNFa mRNA Degradation TNFam
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFam
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

datasource 2
type: dataSource
XREF: BIOMD0000000889
NAME: BioModels Database

RIGHT 0 conversion IFNaenv Translation Secretion IFNaenv
type: physicalEntityParticipant
PHYSICAL-ENTITY: IFNaenv
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

http://identifiers.org/pubmed/24594370
type: publicationXref
ID: 24594370
DB: PubMed

datasource 1
type: dataSource
XREF: MODEL1912120001
NAME: BioModels Database

C128883
type: unificationXref
ID: C128883

C20612
type: unificationXref
ID: C20612
DB: NCIt

LEFT 0 conversion STAT Degradation STAT
type: physicalEntityParticipant
PHYSICAL-ENTITY: STAT
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

PR:000044797
type: unificationXref
ID: PR:000044797
DB: Protein Ontology

PR:000000134
type: unificationXref
ID: PR:000000134

RIGHT 0 conversion TNFa mRNA Induction TNFam
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFam
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion STATP2n Formation STATP2n
type: physicalEntityParticipant
PHYSICAL-ENTITY: STATP2n
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0