LEFT 0 conversion Clb1 2 degradation binary Cdk1 Clb1or2
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb1or2
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion Clb3 4 degradation binary Cdk1 Clb3or4
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb3or4
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion Sic1 binding to Cdk1 Clb1 2 Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion Sic1 degradation basal Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion Clb5 6 degradation binary Cdk1 Clb5or6
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb5or6
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

P00546
type: unificationXref
ID: P00546
DB: UniProt Knowledgebase

LEFT 0 conversion Sic1 degradation Clb regulated 1 Cdk1 Clb1or2 Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb1or2 Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion Sic1 degradation Clb regulated 2 Sic1 degraded re18
type: physicalEntityParticipant
PHYSICAL-ENTITY: Sic1 degraded re18
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

P38634
type: unificationXref
ID: P38634
DB: UniProt Knowledgebase

C25650
type: unificationXref
ID: C25650

RIGHT 0 conversion Cdk1 Clb5 6 Sic1 dissociation Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

P24869
type: unificationXref
ID: P24869
DB: UniProt Knowledgebase

RIGHT 0 conversion Sic1 binding to Cdk1 Clb3 4 Cdk1 Clb3or4 Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb3or4 Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

P24870
type: unificationXref
ID: P24870
DB: UniProt Knowledgebase

RIGHT 0 conversion Cdk1 Clb1 2 production Cdk1 Clb1or2
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb1or2
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion Clb5 6 degradation ternary Cdk1 Clb5or6 Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb5or6 Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion Sic1 binding to Cdk1 Clb3 4 Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion Clb5 6 degradation binary Clb5or6 degraded
type: physicalEntityParticipant
PHYSICAL-ENTITY: Clb5or6 degraded
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

cell
type: openControlledVocabulary
XREF: GO:0005623
TERM: cell

C14271
type: unificationXref
ID: C14271
DB: NCIt

LEFT 0 conversion Cdk1 Clb5 6 Sic1 dissociation Cdk1 Clb5or6 Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb5or6 Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion Cdk1 Clb1 2 Sic1 dissociation Cdk1 Clb1or2 Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb1or2 Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion Cdk1 Clb3 4 Sic1 dissociation Cdk1 Clb3or4 Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb3or4 Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

conversion Cdk1 Clb3 4 production
type: complexAssembly
XREF: C61408
SPONTANEOUS: L_R
RIGHT: RIGHT 0 conversion Cdk1 Clb3 4 production Cdk1 Clb3or4

conversion Clb1 2 degradation binary
type: complexAssembly
XREF: C18104
LEFT: LEFT 0 conversion Clb1 2 degradation binary Cdk1 Clb1or2
SPONTANEOUS: R_L
RIGHT: RIGHT 0 conversion Clb1 2 degradation binary Clb1or2 degraded

RIGHT 1 conversion Cdk1 Clb1 2 Sic1 dissociation Cdk1 Clb1or2
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb1or2
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion Sic1 binding to Cdk1 Clb5 6 Cdk1 Clb5or6 Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb5or6 Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

GO:0032991
type: unificationXref
ID: GO:0032991
DB: Gene Ontology

conversion Cdk1 Clb5 6 production
type: complexAssembly
XREF: C61408
SPONTANEOUS: L_R
RIGHT: RIGHT 0 conversion Cdk1 Clb5 6 production Cdk1 Clb5or6

LEFT 0 conversion Sic1 degradation Clb regulated Cdk1 Clb5or6 Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb5or6 Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

BIOMD0000000934
type: unificationXref
ID: BIOMD0000000934
DB: BioModels Database

RIGHT 0 conversion Cdk1 Clb3 4 Sic1 dissociation Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion Cdk1 Clb3 4 production Cdk1 Clb3or4
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb3or4
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion Sic1 degradation Clb regulated 2 Cdk1 Clb3or4 Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb3or4 Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

C18104
type: unificationXref
ID: C18104
DB: NCIt

P30283
type: unificationXref
ID: P30283
DB: UniProt Knowledgebase

LEFT 0 conversion Clb3 4 degradation ternary Cdk1 Clb3or4 Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb3or4 Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion Sic1 binding to Cdk1 Clb1 2 Cdk1 Clb1or2
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb1or2
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion Clb3 4 degradation binary Clb3or4 degraded
type: physicalEntityParticipant
PHYSICAL-ENTITY: Clb3or4 degraded
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion Clb3 4 degradation ternary Clb3or4 degraded
type: physicalEntityParticipant
PHYSICAL-ENTITY: Clb3or4 degraded
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

conversion Clb3 4 degradation ternary
type: complexAssembly
XREF: C18104
LEFT: LEFT 0 conversion Clb3 4 degradation ternary Cdk1 Clb3or4 Sic1
SPONTANEOUS: R_L
RIGHT: RIGHT 0 conversion Clb3 4 degradation ternary Clb3or4 degraded

MAMO_0000046
type: unificationXref
ID: MAMO_0000046
DB: Mathematical Modelling Ontology

RIGHT 0 conversion Sic1 degradation Clb regulated 1 Sic1 degraded re14
type: physicalEntityParticipant
PHYSICAL-ENTITY: Sic1 degraded re14
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion Sic1 degradation Clb regulated Cdk1 Clb5or6
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb5or6
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

http://identifiers.org/pubmed/28649434
type: publicationXref
ID: 28649434
DB: PubMed

LEFT 1 conversion Sic1 binding to Cdk1 Clb3 4 Cdk1 Clb3or4
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb3or4
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion Cdk1 Clb1 2 Sic1 dissociation Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion Clb1 2 degradation ternary Clb1or2 degraded
type: physicalEntityParticipant
PHYSICAL-ENTITY: Clb1or2 degraded
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 1 conversion Cdk1 Clb5 6 Sic1 dissociation Cdk1 Clb5or6
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb5or6
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

conversion Clb3 4 degradation binary
type: complexAssembly
XREF: C18104
LEFT: LEFT 0 conversion Clb3 4 degradation binary Cdk1 Clb3or4
SPONTANEOUS: R_L
RIGHT: RIGHT 0 conversion Clb3 4 degradation binary Clb3or4 degraded

RIGHT 0 conversion Cdk1 Clb5 6 production Cdk1 Clb5or6
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb5or6
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion Sic1 binding to Cdk1 Clb5 6 Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

conversion Cdk1 Clb1 2 production
type: complexAssembly
XREF: C61408
SPONTANEOUS: L_R
RIGHT: RIGHT 0 conversion Cdk1 Clb1 2 production Cdk1 Clb1or2

MODEL1809050002
type: unificationXref
ID: MODEL1809050002
DB: BioModels Database

GO:0051726
type: unificationXref
ID: GO:0051726
DB: Gene Ontology

conversion Clb5 6 degradation binary
type: complexAssembly
XREF: C18104
LEFT: LEFT 0 conversion Clb5 6 degradation binary Cdk1 Clb5or6
SPONTANEOUS: R_L
RIGHT: RIGHT 0 conversion Clb5 6 degradation binary Clb5or6 degraded

LEFT 1 conversion Sic1 binding to Cdk1 Clb5 6 Cdk1 Clb5or6
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb5or6
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

GO:0005623
type: unificationXref
ID: GO:0005623
DB: Gene Ontology

GO:0044877
type: unificationXref
ID: GO:0044877
DB: Gene Ontology

RIGHT 1 conversion Cdk1 Clb3 4 Sic1 dissociation Cdk1 Clb3or4
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb3or4
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion Clb1 2 degradation ternary Cdk1 Clb1or2 Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb1or2 Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion Clb1 2 degradation binary Clb1or2 degraded
type: physicalEntityParticipant
PHYSICAL-ENTITY: Clb1or2 degraded
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

datasource 2
type: dataSource
XREF: BIOMD0000000934
NAME: BioModels Database

conversion Clb1 2 degradation ternary
type: complexAssembly
XREF: C18104
LEFT: LEFT 0 conversion Clb1 2 degradation ternary Cdk1 Clb1or2 Sic1
SPONTANEOUS: R_L
RIGHT: RIGHT 0 conversion Clb1 2 degradation ternary Clb1or2 degraded

RIGHT 1 conversion Sic1 degradation Clb regulated Sic1 degraded re5
type: physicalEntityParticipant
PHYSICAL-ENTITY: Sic1 degraded re5
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

C61408
type: unificationXref
ID: C61408
DB: NCIt

Linke2017 Synchronization of Cyclins expression by the Fkh2 transcription factor in the budding yeast cell cycle
type: pathway
XREF: MODEL1809050002
XREF: BIOMD0000000934
XREF: http://identifiers.org/pubmed/28649434
XREF: GO:0051726
XREF: C14271
XREF: MAMO_0000046
PATHWAY-COMPONENTS: conversion Cdk1 Clb3 4 production
PATHWAY-COMPONENTS: conversion Clb3 4 degradation binary
PATHWAY-COMPONENTS: conversion Cdk1 Clb1 2 production
PATHWAY-COMPONENTS: conversion Sic1 binding to Cdk1 Clb3 4
PATHWAY-COMPONENTS: conversion Cdk1 Clb3 4 Sic1 dissociation
PATHWAY-COMPONENTS: conversion Sic1 degradation Clb regulated
PATHWAY-COMPONENTS: conversion Cdk1 Clb5 6 production
PATHWAY-COMPONENTS: conversion Sic1 binding to Cdk1 Clb1 2
PATHWAY-COMPONENTS: conversion Clb5 6 degradation ternary
PATHWAY-COMPONENTS: conversion Sic1 degradation basal
PATHWAY-COMPONENTS: conversion Clb1 2 degradation binary
PATHWAY-COMPONENTS: conversion Clb5 6 degradation binary
PATHWAY-COMPONENTS: conversion Sic1 binding to Cdk1 Clb5 6
PATHWAY-COMPONENTS: conversion Clb3 4 degradation ternary
PATHWAY-COMPONENTS: conversion Cdk1 Clb1 2 Sic1 dissociation
PATHWAY-COMPONENTS: conversion Sic1 degradation Clb regulated 1
PATHWAY-COMPONENTS: conversion Sic1 degradation Clb regulated 2
PATHWAY-COMPONENTS: conversion Clb1 2 degradation ternary
PATHWAY-COMPONENTS: conversion Cdk1 Clb5 6 Sic1 dissociation
COMMENT: The original model, 'Linke2017___Synchronization_of_Cyclins__expression_by_the_Fkh2_transcription_factor_in_the_budding_yeast_cell_cycle', was published in BioModels Database (http://www.ebi.ac.uk/biomodels/).
COMMENT: This BioPAX Level2 file was automatically generated on Apr 8, 2022 by SBML2BioPAX-3.1, BioModels.net, EMBL-EBI.
DATA-SOURCE: datasource 2
DATA-SOURCE: datasource 1

RIGHT 0 conversion Clb5 6 degradation ternary Clb5or6 degraded
type: physicalEntityParticipant
PHYSICAL-ENTITY: Clb5or6 degraded
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0

datasource 1
type: dataSource
XREF: MODEL1809050002
NAME: BioModels Database

conversion Sic1 degradation Clb regulated 2
type: complexAssembly
LEFT: LEFT 0 conversion Sic1 degradation Clb regulated 2 Cdk1 Clb3or4 Sic1
SPONTANEOUS: R_L
RIGHT: RIGHT 0 conversion Sic1 degradation Clb regulated 2 Sic1 degraded re18

conversion Sic1 degradation Clb regulated 1
type: complexAssembly
LEFT: LEFT 0 conversion Sic1 degradation Clb regulated 1 Cdk1 Clb1or2 Sic1
SPONTANEOUS: R_L
RIGHT: RIGHT 0 conversion Sic1 degradation Clb regulated 1 Sic1 degraded re14

conversion Clb5 6 degradation ternary
type: complexAssembly
XREF: C18104
LEFT: LEFT 0 conversion Clb5 6 degradation ternary Cdk1 Clb5or6 Sic1
SPONTANEOUS: R_L
RIGHT: RIGHT 0 conversion Clb5 6 degradation ternary Clb5or6 degraded

RIGHT 0 conversion Sic1 binding to Cdk1 Clb1 2 Cdk1 Clb1or2 Sic1
type: physicalEntityParticipant
PHYSICAL-ENTITY: Cdk1 Clb1or2 Sic1
CELLULAR-LOCATION: cell
STOICHIOMETRIC-COEFFICIENT: 1.0