LEFT 1 conversion Sic1 binding to Cdk1 Clb5 6 Cdk1 Clb5or6 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb5or6
stoichiometric coefficient: 1.0

Sic1
type: Protein
xref: P38634

Cdk1_Clb3or4
type: Complex
xref: GO:0032991
xref: P24870
xref: P00546

Cdk1_Clb1or2
type: PhysicalEntity
member physical entity: Cdk1_Clb1or2
cellular location: cell

LEFT 0 conversion Sic1 binding to Cdk1 Clb3 4 Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Sic1
stoichiometric coefficient: 1.0

RIGHT 0 conversion Sic1 degradation Clb regulated Cdk1 Clb5or6 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb5or6
stoichiometric coefficient: 1.0

Cdk1_Clb3or4
type: PhysicalEntity
member physical entity: Cdk1_Clb3or4
cellular location: cell

Sic1
type: PhysicalEntity
member physical entity: Sic1
cellular location: cell

Sic1
type: PhysicalEntity
member physical entity: Sic1
cellular location: cell

Cdk1_Clb5or6
type: PhysicalEntity
member physical entity: Cdk1_Clb5or6
cellular location: cell

P00546
type: UnificationXref
id: P00546
db: UniProt Knowledgebase

LEFT 0 conversion Sic1 degradation Clb regulated Cdk1 Clb5or6 Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb5or6_Sic1
stoichiometric coefficient: 1.0

Cdk1_Clb1or2_Sic1
type: PhysicalEntity
member physical entity: Cdk1_Clb1or2_Sic1
cellular location: cell

Cdk1_Clb3or4_Sic1
type: Complex
xref: GO:0032991
xref: P24870
xref: P38634
xref: P00546

Clb5or6_degraded
type: Protein
xref: P30283
xref: C25650

Sic1 binding to Cdk1-Clb3,4
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion Sic1 binding to Cdk1 Clb3 4 Cdk1 Clb3or4 Sic1 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Sic1 binding to Cdk1 Clb3 4 Sic1 STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion Sic1 binding to Cdk1 Clb3 4 Cdk1 Clb3or4 STOICHIOMETRY
xref: GO:0044877
right: Cdk1_Clb3or4_Sic1
left: Cdk1_Clb3or4
left: Sic1

Sic1_degraded_re18
type: PhysicalEntity
member physical entity: Sic1_degraded_re18
cellular location: cell

RIGHT 1 conversion Cdk1 Clb5 6 Sic1 dissociation Cdk1 Clb5or6 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb5or6
stoichiometric coefficient: 1.0

P38634
type: UnificationXref
id: P38634
db: UniProt Knowledgebase

C25650
type: UnificationXref
id: C25650

Sic1
type: PhysicalEntity
member physical entity: Sic1
cellular location: cell

RIGHT 0 conversion Clb5 6 degradation ternary Clb5or6 degraded STOICHIOMETRY
type: Stoichiometry
physical entity: Clb5or6_degraded
stoichiometric coefficient: 1.0

P24869
type: UnificationXref
id: P24869
db: UniProt Knowledgebase

Cdk1_Clb3or4_Sic1
type: PhysicalEntity
member physical entity: Cdk1_Clb3or4_Sic1
cellular location: cell

P24870
type: UnificationXref
id: P24870
db: UniProt Knowledgebase

Cdk1_Clb1or2
type: PhysicalEntity
member physical entity: Cdk1_Clb1or2
cellular location: cell

LEFT 0 conversion Clb5 6 degradation binary Cdk1 Clb5or6 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb5or6
stoichiometric coefficient: 1.0

LEFT 0 conversion Sic1 degradation Clb regulated 2 Cdk1 Clb3or4 Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb3or4_Sic1
stoichiometric coefficient: 1.0

LEFT 0 conversion Cdk1 Clb3 4 Sic1 dissociation Cdk1 Clb3or4 Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb3or4_Sic1
stoichiometric coefficient: 1.0

Clb1or2_degraded
type: Protein
xref: C25650
xref: P24869

RIGHT 0 conversion Sic1 binding to Cdk1 Clb5 6 Cdk1 Clb5or6 Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb5or6_Sic1
stoichiometric coefficient: 1.0

Cdk1_Clb1or2
type: Complex
xref: GO:0032991
xref: P24869
xref: P00546

Cdk1_Clb5or6_Sic1
type: PhysicalEntity
member physical entity: Cdk1_Clb5or6_Sic1
cellular location: cell

LEFT 0 conversion Clb1 2 degradation binary Cdk1 Clb1or2 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb1or2
stoichiometric coefficient: 1.0

Sic1_degraded_re18
type: Protein
xref: P38634
xref: C25650

Sic1
type: PhysicalEntity
member physical entity: Sic1
cellular location: cell

Clb5or6_degraded
type: PhysicalEntity
member physical entity: Clb5or6_degraded
cellular location: cell

cell
type: CellularLocationVocabulary
xref: GO:0005623

RIGHT 0 conversion Cdk1 Clb5 6 production Cdk1 Clb5or6 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb5or6
stoichiometric coefficient: 1.0

Cdk1_Clb5or6_Sic1
type: Complex
xref: P30283
xref: GO:0032991
xref: P38634
xref: P00546

C14271
type: UnificationXref
id: C14271
db: NCIt

Sic1 degradation (Clb-regulated)
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion Sic1 degradation Clb regulated Cdk1 Clb5or6 Sic1 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion Sic1 degradation Clb regulated Sic1 degraded re5 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Sic1 degradation Clb regulated Cdk1 Clb5or6 STOICHIOMETRY
right: Cdk1_Clb5or6
right: Sic1_degraded_re5
left: Cdk1_Clb5or6_Sic1

Clb12_total
type: Protein
xref: P24869

Cdk1_Clb5or6_Sic1
type: PhysicalEntity
member physical entity: Cdk1_Clb5or6_Sic1
cellular location: cell

Cdk1_Clb1or2_Sic1
type: PhysicalEntity
member physical entity: Cdk1_Clb1or2_Sic1
cellular location: cell

Cdk1_Clb3or4_Sic1
type: PhysicalEntity
member physical entity: Cdk1_Clb3or4_Sic1
cellular location: cell

Sic1_degraded_re14
type: Protein
xref: P38634
xref: C25650

RIGHT 0 conversion Cdk1 Clb5 6 Sic1 dissociation Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Sic1
stoichiometric coefficient: 1.0

RIGHT 0 conversion Clb1 2 degradation ternary Clb1or2 degraded STOICHIOMETRY
type: Stoichiometry
physical entity: Clb1or2_degraded
stoichiometric coefficient: 1.0

RIGHT 0 conversion Clb1 2 degradation binary Clb1or2 degraded STOICHIOMETRY
type: Stoichiometry
physical entity: Clb1or2_degraded
stoichiometric coefficient: 1.0

LEFT 1 conversion Sic1 binding to Cdk1 Clb1 2 Cdk1 Clb1or2 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb1or2
stoichiometric coefficient: 1.0

Cdk1-Clb3,4 production
type: ComplexAssembly
participant stoichiometry: RIGHT 0 conversion Cdk1 Clb3 4 production Cdk1 Clb3or4 STOICHIOMETRY
xref: C61408
right: Cdk1_Clb3or4
spontaneous: true
conversion direction: LEFT_TO_RIGHT

Cdk1-Clb1,2-Sic1 dissociation
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion Cdk1 Clb1 2 Sic1 dissociation Cdk1 Clb1or2 Sic1 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Cdk1 Clb1 2 Sic1 dissociation Sic1 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion Cdk1 Clb1 2 Sic1 dissociation Cdk1 Clb1or2 STOICHIOMETRY
right: Cdk1_Clb1or2
right: Sic1
left: Cdk1_Clb1or2_Sic1

Clb1,2 degradation (binary)
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion Clb1 2 degradation binary Cdk1 Clb1or2 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Clb1 2 degradation binary Clb1or2 degraded STOICHIOMETRY
xref: C18104
right: Clb1or2_degraded
spontaneous: true
left: Cdk1_Clb1or2
conversion direction: RIGHT_TO_LEFT

LEFT 0 conversion Clb3 4 degradation ternary Cdk1 Clb3or4 Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb3or4_Sic1
stoichiometric coefficient: 1.0

Cdk1_Clb1or2
type: PhysicalEntity
member physical entity: Cdk1_Clb1or2
cellular location: cell

Cdk1_Clb5or6_Sic1
type: PhysicalEntity
member physical entity: Cdk1_Clb5or6_Sic1
cellular location: cell

RIGHT 0 conversion Sic1 degradation Clb regulated 1 Sic1 degraded re14 STOICHIOMETRY
type: Stoichiometry
physical entity: Sic1_degraded_re14
stoichiometric coefficient: 1.0

GO:0032991
type: UnificationXref
id: GO:0032991
db: Gene Ontology

Cdk1-Clb5,6 production
type: ComplexAssembly
participant stoichiometry: RIGHT 0 conversion Cdk1 Clb5 6 production Cdk1 Clb5or6 STOICHIOMETRY
xref: C61408
right: Cdk1_Clb5or6
spontaneous: true
conversion direction: LEFT_TO_RIGHT

RIGHT 1 conversion Sic1 degradation Clb regulated Sic1 degraded re5 STOICHIOMETRY
type: Stoichiometry
physical entity: Sic1_degraded_re5
stoichiometric coefficient: 1.0

Cdk1_Clb5or6_Sic1
type: PhysicalEntity
member physical entity: Cdk1_Clb5or6_Sic1
cellular location: cell

BIOMD0000000934
type: UnificationXref
id: BIOMD0000000934
db: BioModels Database

LEFT 0 conversion Sic1 binding to Cdk1 Clb1 2 Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Sic1
stoichiometric coefficient: 1.0

Sic1
type: PhysicalEntity
member physical entity: Sic1
cellular location: cell

Cdk1_Clb3or4
type: PhysicalEntity
member physical entity: Cdk1_Clb3or4
cellular location: cell

LEFT 0 conversion Sic1 degradation Clb regulated 1 Cdk1 Clb1or2 Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb1or2_Sic1
stoichiometric coefficient: 1.0

Cdk1_Clb3or4_Sic1
type: PhysicalEntity
member physical entity: Cdk1_Clb3or4_Sic1
cellular location: cell

C18104
type: UnificationXref
id: C18104
db: NCIt

RIGHT 1 conversion Cdk1 Clb1 2 Sic1 dissociation Cdk1 Clb1or2 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb1or2
stoichiometric coefficient: 1.0

P30283
type: UnificationXref
id: P30283
db: UniProt Knowledgebase

RIGHT 0 conversion Sic1 binding to Cdk1 Clb3 4 Cdk1 Clb3or4 Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb3or4_Sic1
stoichiometric coefficient: 1.0

Cdk1_Clb3or4_Sic1
type: PhysicalEntity
member physical entity: Cdk1_Clb3or4_Sic1
cellular location: cell

Sic1 binding to Cdk1-Clb5,6
type: BiochemicalReaction
participant stoichiometry: LEFT 1 conversion Sic1 binding to Cdk1 Clb5 6 Cdk1 Clb5or6 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Sic1 binding to Cdk1 Clb5 6 Cdk1 Clb5or6 Sic1 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Sic1 binding to Cdk1 Clb5 6 Sic1 STOICHIOMETRY
xref: GO:0044877
right: Cdk1_Clb5or6_Sic1
left: Sic1
left: Cdk1_Clb5or6

Cdk1_Clb1or2
type: PhysicalEntity
member physical entity: Cdk1_Clb1or2
cellular location: cell

RIGHT 1 conversion Cdk1 Clb3 4 Sic1 dissociation Cdk1 Clb3or4 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb3or4
stoichiometric coefficient: 1.0

Clb34_total
type: Protein
xref: P24870

LEFT 0 conversion Cdk1 Clb1 2 Sic1 dissociation Cdk1 Clb1or2 Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb1or2_Sic1
stoichiometric coefficient: 1.0

Clb3or4_degraded
type: PhysicalEntity
member physical entity: Clb3or4_degraded
cellular location: cell

RIGHT 0 conversion Cdk1 Clb1 2 production Cdk1 Clb1or2 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb1or2
stoichiometric coefficient: 1.0

RIGHT 0 conversion Cdk1 Clb1 2 Sic1 dissociation Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Sic1
stoichiometric coefficient: 1.0

Clb3or4_degraded
type: PhysicalEntity
member physical entity: Clb3or4_degraded
cellular location: cell

Clb3,4 degradation (ternary)
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion Clb3 4 degradation ternary Cdk1 Clb3or4 Sic1 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Clb3 4 degradation ternary Clb3or4 degraded STOICHIOMETRY
xref: C18104
right: Clb3or4_degraded
spontaneous: true
left: Cdk1_Clb3or4_Sic1
conversion direction: RIGHT_TO_LEFT

LEFT 0 conversion Sic1 degradation basal Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Sic1
stoichiometric coefficient: 1.0

Sic1 binding to Cdk1-Clb1,2
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion Sic1 binding to Cdk1 Clb1 2 Sic1 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Sic1 binding to Cdk1 Clb1 2 Cdk1 Clb1or2 Sic1 STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion Sic1 binding to Cdk1 Clb1 2 Cdk1 Clb1or2 STOICHIOMETRY
xref: GO:0044877
right: Cdk1_Clb1or2_Sic1
left: Cdk1_Clb1or2
left: Sic1

Cdk1-Clb3,4-Sic1 dissociation
type: BiochemicalReaction
participant stoichiometry: RIGHT 1 conversion Cdk1 Clb3 4 Sic1 dissociation Cdk1 Clb3or4 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Cdk1 Clb3 4 Sic1 dissociation Sic1 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Cdk1 Clb3 4 Sic1 dissociation Cdk1 Clb3or4 Sic1 STOICHIOMETRY
right: Cdk1_Clb3or4
right: Sic1
left: Cdk1_Clb3or4_Sic1

MAMO_0000046
type: UnificationXref
id: MAMO_0000046
db: Mathematical Modelling Ontology

Cdk1_Clb1or2_Sic1
type: Complex
xref: GO:0032991
xref: P38634
xref: P00546
xref: P24869

Sic1_degraded_re14
type: PhysicalEntity
member physical entity: Sic1_degraded_re14
cellular location: cell

Sic1 degradation (basal)
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion Sic1 degradation basal Sic1 STOICHIOMETRY
left: Sic1

Cdk1_Clb5or6
type: PhysicalEntity
member physical entity: Cdk1_Clb5or6
cellular location: cell

http://identifiers.org/pubmed/28649434
type: PublicationXref
id: 28649434
db: PubMed

LEFT 0 conversion Cdk1 Clb5 6 Sic1 dissociation Cdk1 Clb5or6 Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb5or6_Sic1
stoichiometric coefficient: 1.0

Cdk1_Clb3or4
type: PhysicalEntity
member physical entity: Cdk1_Clb3or4
cellular location: cell

RIGHT 0 conversion Clb3 4 degradation binary Clb3or4 degraded STOICHIOMETRY
type: Stoichiometry
physical entity: Clb3or4_degraded
stoichiometric coefficient: 1.0

RIGHT 0 conversion Cdk1 Clb3 4 Sic1 dissociation Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Sic1
stoichiometric coefficient: 1.0

Cdk1-Clb5,6-Sic1 dissociation
type: BiochemicalReaction
participant stoichiometry: RIGHT 1 conversion Cdk1 Clb5 6 Sic1 dissociation Cdk1 Clb5or6 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Cdk1 Clb5 6 Sic1 dissociation Cdk1 Clb5or6 Sic1 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Cdk1 Clb5 6 Sic1 dissociation Sic1 STOICHIOMETRY
right: Cdk1_Clb5or6
right: Sic1
left: Cdk1_Clb5or6_Sic1

Sic1
type: PhysicalEntity
member physical entity: Sic1
cellular location: cell

Clb1or2_degraded
type: PhysicalEntity
member physical entity: Clb1or2_degraded
cellular location: cell

Cdk1_Clb5or6
type: PhysicalEntity
member physical entity: Cdk1_Clb5or6
cellular location: cell

Clb3,4 degradation (binary)
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion Clb3 4 degradation binary Cdk1 Clb3or4 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Clb3 4 degradation binary Clb3or4 degraded STOICHIOMETRY
xref: C18104
right: Clb3or4_degraded
spontaneous: true
left: Cdk1_Clb3or4
conversion direction: RIGHT_TO_LEFT

Cdk1_Clb5or6
type: PhysicalEntity
member physical entity: Cdk1_Clb5or6
cellular location: cell

Clb3or4_degraded
type: Protein
xref: P24870
xref: C25650

Sic1
type: PhysicalEntity
member physical entity: Sic1
cellular location: cell

Cdk1-Clb1,2 production
type: ComplexAssembly
participant stoichiometry: RIGHT 0 conversion Cdk1 Clb1 2 production Cdk1 Clb1or2 STOICHIOMETRY
xref: C61408
right: Cdk1_Clb1or2
spontaneous: true
conversion direction: LEFT_TO_RIGHT

MODEL1809050002
type: UnificationXref
id: MODEL1809050002
db: BioModels Database

LEFT 0 conversion Clb3 4 degradation binary Cdk1 Clb3or4 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb3or4
stoichiometric coefficient: 1.0

GO:0051726
type: UnificationXref
id: GO:0051726
db: Gene Ontology

Clb5,6 degradation (binary)
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion Clb5 6 degradation binary Cdk1 Clb5or6 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Clb5 6 degradation binary Clb5or6 degraded STOICHIOMETRY
xref: C18104
right: Clb5or6_degraded
spontaneous: true
left: Cdk1_Clb5or6
conversion direction: RIGHT_TO_LEFT

Cdk1_Clb5or6
type: Complex
xref: P30283
xref: GO:0032991
xref: P00546

Cdk1_Clb5or6
type: PhysicalEntity
member physical entity: Cdk1_Clb5or6
cellular location: cell

GO:0005623
type: UnificationXref
id: GO:0005623
db: Gene Ontology

Sic1_degraded_re5
type: Protein
xref: P38634
xref: C25650

GO:0044877
type: UnificationXref
id: GO:0044877
db: Gene Ontology

LEFT 0 conversion Clb1 2 degradation ternary Cdk1 Clb1or2 Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb1or2_Sic1
stoichiometric coefficient: 1.0

LEFT 0 conversion Sic1 binding to Cdk1 Clb5 6 Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Sic1
stoichiometric coefficient: 1.0

Cdk1_Clb3or4
type: PhysicalEntity
member physical entity: Cdk1_Clb3or4
cellular location: cell

RIGHT 0 conversion Clb3 4 degradation ternary Clb3or4 degraded STOICHIOMETRY
type: Stoichiometry
physical entity: Clb3or4_degraded
stoichiometric coefficient: 1.0

Cdk1_Clb1or2_Sic1
type: PhysicalEntity
member physical entity: Cdk1_Clb1or2_Sic1
cellular location: cell

Clb1or2_degraded
type: PhysicalEntity
member physical entity: Clb1or2_degraded
cellular location: cell

RIGHT 0 conversion Sic1 degradation Clb regulated 2 Sic1 degraded re18 STOICHIOMETRY
type: Stoichiometry
physical entity: Sic1_degraded_re18
stoichiometric coefficient: 1.0

BioModels Database
type: Provenance
xref: BIOMD0000000934

Clb1,2 degradation (ternary)
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion Clb1 2 degradation ternary Cdk1 Clb1or2 Sic1 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Clb1 2 degradation ternary Clb1or2 degraded STOICHIOMETRY
xref: C18104
right: Clb1or2_degraded
spontaneous: true
left: Cdk1_Clb1or2_Sic1
conversion direction: RIGHT_TO_LEFT

Sic1_degraded_re5
type: PhysicalEntity
member physical entity: Sic1_degraded_re5
cellular location: cell

RIGHT 0 conversion Cdk1 Clb3 4 production Cdk1 Clb3or4 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb3or4
stoichiometric coefficient: 1.0

C61408
type: UnificationXref
id: C61408
db: NCIt

LEFT 1 conversion Sic1 binding to Cdk1 Clb3 4 Cdk1 Clb3or4 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb3or4
stoichiometric coefficient: 1.0

LEFT 0 conversion Clb5 6 degradation ternary Cdk1 Clb5or6 Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb5or6_Sic1
stoichiometric coefficient: 1.0

Linke2017 Synchronization of Cyclins expression by the Fkh2 transcription factor in the budding yeast cell cycle
type: Pathway
pathway component: Cdk1-Clb1,2-Sic1 dissociation
pathway component: Clb1,2 degradation (binary)
pathway component: Sic1 binding to Cdk1-Clb5,6
pathway component: Clb1,2 degradation (ternary)
pathway component: Sic1 degradation (basal)
pathway component: Clb5,6 degradation (binary)
pathway component: Cdk1-Clb5,6-Sic1 dissociation
pathway component: Clb3,4 degradation (ternary)
pathway component: Sic1 degradation (Clb-regulated)
pathway component: Clb3,4 degradation (binary)
pathway component: Sic1 degradation (Clb-regulated)_2
pathway component: Sic1 degradation (Clb-regulated)_1
pathway component: Cdk1-Clb5,6 production
pathway component: Clb5,6 degradation (ternary)
pathway component: Sic1 binding to Cdk1-Clb1,2
pathway component: Cdk1-Clb1,2 production
pathway component: Cdk1-Clb3,4-Sic1 dissociation
pathway component: Cdk1-Clb3,4 production
pathway component: Sic1 binding to Cdk1-Clb3,4
xref: C14271
xref: GO:0051726
xref: http://identifiers.org/pubmed/28649434
xref: BIOMD0000000934
xref: MODEL1809050002
xref: MAMO_0000046
comment: This BioPAX Level3 file was automatically generated on Apr 8, 2022 by SBML2BioPAX-3.1, BioModels.net, EMBL-EBI.
comment: The original model, 'Linke2017___Synchronization_of_Cyclins__expression_by_the_Fkh2_transcription_factor_in_the_budding_yeast_cell_cycle', was published in BioModels Database (http://www.ebi.ac.uk/biomodels/).
data source: BioModels Database

Clb5or6_degraded
type: PhysicalEntity
member physical entity: Clb5or6_degraded
cellular location: cell

RIGHT 0 conversion Clb5 6 degradation binary Clb5or6 degraded STOICHIOMETRY
type: Stoichiometry
physical entity: Clb5or6_degraded
stoichiometric coefficient: 1.0

BioModels Database
type: Provenance
xref: MODEL1809050002

Sic1 degradation (Clb-regulated)_2
type: ComplexAssembly
participant stoichiometry: LEFT 0 conversion Sic1 degradation Clb regulated 2 Cdk1 Clb3or4 Sic1 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Sic1 degradation Clb regulated 2 Sic1 degraded re18 STOICHIOMETRY
right: Sic1_degraded_re18
spontaneous: true
left: Cdk1_Clb3or4_Sic1
conversion direction: RIGHT_TO_LEFT

Sic1 degradation (Clb-regulated)_1
type: ComplexAssembly
participant stoichiometry: RIGHT 0 conversion Sic1 degradation Clb regulated 1 Sic1 degraded re14 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Sic1 degradation Clb regulated 1 Cdk1 Clb1or2 Sic1 STOICHIOMETRY
right: Sic1_degraded_re14
spontaneous: true
left: Cdk1_Clb1or2_Sic1
conversion direction: RIGHT_TO_LEFT

Clb56_total
type: Protein
xref: P30283

Clb5,6 degradation (ternary)
type: ComplexAssembly
participant stoichiometry: RIGHT 0 conversion Clb5 6 degradation ternary Clb5or6 degraded STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Clb5 6 degradation ternary Cdk1 Clb5or6 Sic1 STOICHIOMETRY
xref: C18104
right: Clb5or6_degraded
spontaneous: true
left: Cdk1_Clb5or6_Sic1
conversion direction: RIGHT_TO_LEFT

Cdk1_Clb1or2_Sic1
type: PhysicalEntity
member physical entity: Cdk1_Clb1or2_Sic1
cellular location: cell

RIGHT 0 conversion Sic1 binding to Cdk1 Clb1 2 Cdk1 Clb1or2 Sic1 STOICHIOMETRY
type: Stoichiometry
physical entity: Cdk1_Clb1or2_Sic1
stoichiometric coefficient: 1.0