LEFT 1 conversion J88 Casp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: Casp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J27 TNFRC2 pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J13 TNFRC2 FLIP FLIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 FLIP FLIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J59 IkBa
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

ENST00000216797
type: unificationXref
ID: ENST00000216797
DB: Ensembl

LEFT 0 conversion J18 TNFR E
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFR E
CELLULAR-LOCATION: extracellular
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J47 PIkBa
type: physicalEntityParticipant
PHYSICAL-ENTITY: PIkBa
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion J82 Casp3
type: physicalEntityParticipant
PHYSICAL-ENTITY: Casp3
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J65 XIAP
type: physicalEntityParticipant
PHYSICAL-ENTITY: XIAP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

GO:0005576
type: unificationXref
ID: GO:0005576
DB: Gene Ontology

RIGHT 0 conversion J52 IKK
type: physicalEntityParticipant
PHYSICAL-ENTITY: IKK
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J5 TRADD
type: physicalEntityParticipant
PHYSICAL-ENTITY: TRADD
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

P01375
type: unificationXref
ID: P01375
DB: UniProt Knowledgebase

LEFT 0 conversion J87 PARP
type: physicalEntityParticipant
PHYSICAL-ENTITY: PARP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J25 TNFRC2 FLIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 FLIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

O15111
type: unificationXref
ID: O15111
DB: UniProt Knowledgebase

LEFT 0 conversion J81 pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

http://identifiers.org/pubmed/22204418
type: publicationXref
ID: 22204418
DB: PubMed

RIGHT 1 conversion J29 Casp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: Casp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

P98170
type: unificationXref
ID: P98170
DB: UniProt Knowledgebase

RIGHT 0 conversion J37 FLIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: FLIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J78 cPARP
type: physicalEntityParticipant
PHYSICAL-ENTITY: cPARP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J88 BAR Casp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: BAR Casp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J77 PARP
type: physicalEntityParticipant
PHYSICAL-ENTITY: PARP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J33 TNFRC2 FLIP pCasp8 RIP TRAF2
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 FLIP pCasp8 RIP TRAF2
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J36 NFkB
type: physicalEntityParticipant
PHYSICAL-ENTITY: NFkB
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

map04210
type: unificationXref
ID: map04210
DB: KEGG Pathway

P42574
type: unificationXref
ID: P42574
DB: UniProt Knowledgebase

RIGHT 0 conversion J29 TNFRC2
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

BIOMD0000000407
type: unificationXref
ID: BIOMD0000000407
DB: BioModels Database

LEFT 0 conversion J45 IkBa N
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa N
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J59 IkBa N
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa N
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J32 TNFRC2
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J61 IkBa NFkB
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa NFkB
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

ENST00000309955
type: unificationXref
ID: ENST00000309955
DB: Ensembl

LEFT 0 conversion J1 TNFR
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFR
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J16 TNFRC2 FLIP pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 FLIP pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J64 XIAP mRNA
type: physicalEntityParticipant
PHYSICAL-ENTITY: XIAP mRNA
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J76 BAR Casp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: BAR Casp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion J54 IkBa
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 2 conversion J22 TNFRCint2
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRCint2
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J88 BAR
type: physicalEntityParticipant
PHYSICAL-ENTITY: BAR
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 1 conversion J22 TRAF2
type: physicalEntityParticipant
PHYSICAL-ENTITY: TRAF2
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion J23 TNFRCint2
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRCint2
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J55 IkBa NFkB
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa NFkB
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J48 A20 mRNA
type: physicalEntityParticipant
PHYSICAL-ENTITY: A20 mRNA
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J54 IkBa NFkB
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa NFkB
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion J18 TNF E
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNF E
CELLULAR-LOCATION: extracellular
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J71 Casp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: Casp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J15 TNFRC2 pCasp8 pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 pCasp8 pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion J19 TRADD
type: physicalEntityParticipant
PHYSICAL-ENTITY: TRADD
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J55 NFkB
type: physicalEntityParticipant
PHYSICAL-ENTITY: NFkB
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion J20 TRAF2
type: physicalEntityParticipant
PHYSICAL-ENTITY: TRAF2
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J80 Casp6
type: physicalEntityParticipant
PHYSICAL-ENTITY: Casp6
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J30 FLIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: FLIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J20 RIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: RIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J27 TNFRC2
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J66 FLIP mRNA
type: physicalEntityParticipant
PHYSICAL-ENTITY: FLIP mRNA
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J30 TNFRC2 FLIP pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 FLIP pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J74 XIAP Casp3
type: physicalEntityParticipant
PHYSICAL-ENTITY: XIAP Casp3
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J60 NFkB N
type: physicalEntityParticipant
PHYSICAL-ENTITY: NFkB N
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J25 TNFRC2
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J8 TNF TNFR E
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNF TNFR E
CELLULAR-LOCATION: extracellular
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J50 FLIP mRNA
type: physicalEntityParticipant
PHYSICAL-ENTITY: FLIP mRNA
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion J25 FLIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: FLIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J84 XIAP
type: physicalEntityParticipant
PHYSICAL-ENTITY: XIAP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J54 NFkB
type: physicalEntityParticipant
PHYSICAL-ENTITY: NFkB
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J38 XIAP
type: physicalEntityParticipant
PHYSICAL-ENTITY: XIAP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 1 conversion J32 Casp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: Casp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J87 cPARP
type: physicalEntityParticipant
PHYSICAL-ENTITY: cPARP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

MODEL1112210000
type: unificationXref
ID: MODEL1112210000
DB: BioModels Database

LEFT 0 conversion J31 TNFRC2 FLIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 FLIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J17 TNFRC2 FLIP pCasp8 RIP TRAF2
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 FLIP pCasp8 RIP TRAF2
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J14 TNFRC2 pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J19 TNF TNFR E
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNF TNFR E
CELLULAR-LOCATION: extracellular
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J11 TNFRC2
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J67 FLIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: FLIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J21 TNFRCint1
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRCint1
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

P19438
type: unificationXref
ID: P19438
DB: UniProt Knowledgebase

RIGHT 0 conversion J34 IKKa
type: physicalEntityParticipant
PHYSICAL-ENTITY: IKKa
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J69 pCasp3
type: physicalEntityParticipant
PHYSICAL-ENTITY: pCasp3
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

ENST00000371199
type: unificationXref
ID: ENST00000371199
DB: Ensembl

RIGHT 0 conversion J19 TNF TNFR TRADD
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNF TNFR TRADD
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

P09874
type: unificationXref
ID: P09874
DB: UniProt Knowledgebase

RIGHT 0 conversion J56 NFkB N
type: physicalEntityParticipant
PHYSICAL-ENTITY: NFkB N
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J28 TNFRC2 pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

GO:0005634
type: unificationXref
ID: GO:0005634
DB: Gene Ontology

Q13546
type: unificationXref
ID: Q13546
DB: UniProt Knowledgebase

RIGHT 0 conversion J1 TNFR E
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFR E
CELLULAR-LOCATION: extracellular
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 1 conversion J55 PIkBa
type: physicalEntityParticipant
PHYSICAL-ENTITY: PIkBa
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J3 TNFR E
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFR E
CELLULAR-LOCATION: extracellular
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J40 IKKa
type: physicalEntityParticipant
PHYSICAL-ENTITY: IKKa
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion J26 TNFRC2 FLIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 FLIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J82 XIAP
type: physicalEntityParticipant
PHYSICAL-ENTITY: XIAP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J26 FLIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: FLIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J63 A20
type: physicalEntityParticipant
PHYSICAL-ENTITY: A20
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J22 RIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: RIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J23 TNFRCint3
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRCint3
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J82 XIAP Casp3
type: physicalEntityParticipant
PHYSICAL-ENTITY: XIAP Casp3
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J79 pCasp3
type: physicalEntityParticipant
PHYSICAL-ENTITY: pCasp3
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J51 IKK
type: physicalEntityParticipant
PHYSICAL-ENTITY: IKK
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J32 TNFRC2 FLIP pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 FLIP pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

O15519
type: unificationXref
ID: O15519
DB: UniProt Knowledgebase

LEFT 0 conversion J29 TNFRC2 pCasp8 pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 pCasp8 pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

Q12933
type: unificationXref
ID: Q12933
DB: UniProt Knowledgebase

LEFT 0 conversion J22 TNFRCint1
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRCint1
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J7 FADD
type: physicalEntityParticipant
PHYSICAL-ENTITY: FADD
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J20 TNFRC1
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC1
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J75 BAR
type: physicalEntityParticipant
PHYSICAL-ENTITY: BAR
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J85 RIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: RIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

GO:0005737
type: unificationXref
ID: GO:0005737
DB: Gene Ontology

RIGHT 0 conversion J24 TNFRC2
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J31 TNFRC2 FLIP pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 FLIP pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J44 IkBa
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

P25963
type: unificationXref
ID: P25963
DB: UniProt Knowledgebase

RIGHT 0 conversion J53 TRAF2
type: physicalEntityParticipant
PHYSICAL-ENTITY: TRAF2
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J12 TNFRC2 FLIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 FLIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J42 NFkB N
type: physicalEntityParticipant
PHYSICAL-ENTITY: NFkB N
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

GO:0006915
type: unificationXref
ID: GO:0006915
DB: Gene Ontology

RIGHT 0 conversion J2 TNFR
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFR
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion J31 pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J72 Casp3
type: physicalEntityParticipant
PHYSICAL-ENTITY: Casp3
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J81 Casp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: Casp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J28 TNFRC2 pCasp8 pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 pCasp8 pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

BTO:0002267
type: unificationXref
ID: BTO:0002267
DB: Brenda Tissue Ontology

RIGHT 0 conversion J26 TNFRC2 FLIP FLIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 FLIP FLIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

Q15628
type: unificationXref
ID: Q15628
DB: UniProt Knowledgebase

LEFT 0 conversion J73 Casp6
type: physicalEntityParticipant
PHYSICAL-ENTITY: Casp6
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J68 pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J39 A20
type: physicalEntityParticipant
PHYSICAL-ENTITY: A20
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J83 XIAP
type: physicalEntityParticipant
PHYSICAL-ENTITY: XIAP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

Q14790
type: unificationXref
ID: Q14790
DB: UniProt Knowledgebase

LEFT 0 conversion J53 TNFRC1
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC1
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J51 IKKa
type: physicalEntityParticipant
PHYSICAL-ENTITY: IKKa
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J6 TRAF2
type: physicalEntityParticipant
PHYSICAL-ENTITY: TRAF2
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

nucleus
type: openControlledVocabulary
XREF: GO:0005634
TERM: nucleus

RIGHT 0 conversion J57 IkBa mRNA
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa mRNA
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J80 pCasp6
type: physicalEntityParticipant
PHYSICAL-ENTITY: pCasp6
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J4 RIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: RIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

Q13158
type: unificationXref
ID: Q13158
DB: UniProt Knowledgebase

RIGHT 1 conversion J53 TNF TNFR TRADD
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNF TNFR TRADD
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J58 IkBa
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

ENST00000237289
type: unificationXref
ID: ENST00000237289
DB: Ensembl

LEFT 1 conversion J27 pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion J33 TRAF2
type: physicalEntityParticipant
PHYSICAL-ENTITY: TRAF2
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

http://identifiers.org/taxonomy/9606
type: unificationXref
ID: 9606
DB: Taxonomy

LEFT 0 conversion J34 IKK
type: physicalEntityParticipant
PHYSICAL-ENTITY: IKK
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J70 pCasp6
type: physicalEntityParticipant
PHYSICAL-ENTITY: pCasp6
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J52 IKKa
type: physicalEntityParticipant
PHYSICAL-ENTITY: IKKa
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

Q9NZS9
type: unificationXref
ID: Q9NZS9
DB: UniProt Knowledgebase

LEFT 0 conversion J24 TNFRCint3
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRCint3
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J21 TNFRC1
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC1
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion J28 pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J84 XIAP Casp3
type: physicalEntityParticipant
PHYSICAL-ENTITY: XIAP Casp3
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion J30 TNFRC2 pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 2 conversion J33 TNFRC2 FLIP pCasp8
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC2 FLIP pCasp8
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J9 TNF TNFR TRADD
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNF TNFR TRADD
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J35 IKK
type: physicalEntityParticipant
PHYSICAL-ENTITY: IKK
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J43 IkBa mRNA
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa mRNA
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J62 A20 mRNA
type: physicalEntityParticipant
PHYSICAL-ENTITY: A20 mRNA
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J46 IkBa NFkB N
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa NFkB N
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

Schliemann2011 TNF ProAntiApoptosis
type: pathway
XREF: http://identifiers.org/pubmed/22204418
XREF: MODEL1112210000
XREF: BTO:0002267
XREF: map04210
XREF: GO:0006915
XREF: BIOMD0000000407
PATHWAY-COMPONENTS: conversion J81
PATHWAY-COMPONENTS: conversion J80
PATHWAY-COMPONENTS: conversion J56
PATHWAY-COMPONENTS: conversion J43
PATHWAY-COMPONENTS: conversion J87
PATHWAY-COMPONENTS: conversion J42
PATHWAY-COMPONENTS: conversion J86
PATHWAY-COMPONENTS: conversion J45
PATHWAY-COMPONENTS: conversion J44
PATHWAY-COMPONENTS: conversion J59
PATHWAY-COMPONENTS: conversion J88
PATHWAY-COMPONENTS: conversion J83
PATHWAY-COMPONENTS: conversion J82
PATHWAY-COMPONENTS: conversion J41
PATHWAY-COMPONENTS: conversion J85
PATHWAY-COMPONENTS: conversion J19
PATHWAY-COMPONENTS: conversion J40
PATHWAY-COMPONENTS: conversion J84
PATHWAY-COMPONENTS: conversion J39
PATHWAY-COMPONENTS: conversion J36
PATHWAY-COMPONENTS: conversion J35
PATHWAY-COMPONENTS: conversion J79
PATHWAY-COMPONENTS: conversion J38
PATHWAY-COMPONENTS: conversion J37
PATHWAY-COMPONENTS: conversion J61
PATHWAY-COMPONENTS: conversion J70
PATHWAY-COMPONENTS: conversion J32
PATHWAY-COMPONENTS: conversion J76
PATHWAY-COMPONENTS: conversion J31
PATHWAY-COMPONENTS: conversion J75
PATHWAY-COMPONENTS: conversion J34
PATHWAY-COMPONENTS: conversion J78
PATHWAY-COMPONENTS: conversion J33
PATHWAY-COMPONENTS: conversion J77
PATHWAY-COMPONENTS: conversion J72
PATHWAY-COMPONENTS: conversion J71
PATHWAY-COMPONENTS: conversion J30
PATHWAY-COMPONENTS: conversion J74
PATHWAY-COMPONENTS: conversion J73
PATHWAY-COMPONENTS: conversion J29
PATHWAY-COMPONENTS: conversion J28
PATHWAY-COMPONENTS: conversion J25
PATHWAY-COMPONENTS: conversion J69
PATHWAY-COMPONENTS: conversion J24
PATHWAY-COMPONENTS: conversion J68
PATHWAY-COMPONENTS: conversion J27
PATHWAY-COMPONENTS: conversion J26
PATHWAY-COMPONENTS: conversion J21
PATHWAY-COMPONENTS: conversion J65
PATHWAY-COMPONENTS: conversion J20
PATHWAY-COMPONENTS: conversion J64
PATHWAY-COMPONENTS: conversion J23
PATHWAY-COMPONENTS: conversion J67
PATHWAY-COMPONENTS: conversion J22
PATHWAY-COMPONENTS: conversion J66
PATHWAY-COMPONENTS: conversion J60
PATHWAY-COMPONENTS: conversion J63
PATHWAY-COMPONENTS: conversion J62
PATHWAY-COMPONENTS: conversion J18
PATHWAY-COMPONENTS: conversion J17
PATHWAY-COMPONENTS: conversion J14
PATHWAY-COMPONENTS: conversion J58
PATHWAY-COMPONENTS: conversion J1
PATHWAY-COMPONENTS: conversion J13
PATHWAY-COMPONENTS: conversion J57
PATHWAY-COMPONENTS: conversion J16
PATHWAY-COMPONENTS: conversion J15
PATHWAY-COMPONENTS: conversion J6
PATHWAY-COMPONENTS: conversion J7
PATHWAY-COMPONENTS: conversion J8
PATHWAY-COMPONENTS: conversion J9
PATHWAY-COMPONENTS: conversion J2
PATHWAY-COMPONENTS: conversion J10

cytoplasm
type: openControlledVocabulary
XREF: GO:0005737
TERM: cytoplasm

LEFT 0 conversion J10 TNFRC1
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNFRC1
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J41 IkBa NFkB
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa NFkB
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion J60 IkBa N
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa N
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J86 FLIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: FLIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

P19838
type: unificationXref
ID: P19838
DB: UniProt Knowledgebase

LEFT 0 conversion J33 RIP
type: physicalEntityParticipant
PHYSICAL-ENTITY: RIP
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

datasource 2
type: dataSource
XREF: BIOMD0000000407
NAME: BioModels Database

extracellular
type: openControlledVocabulary
XREF: GO:0005576
TERM: extracellular

LEFT 0 conversion J23 FADD
type: physicalEntityParticipant
PHYSICAL-ENTITY: FADD
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 2.0

RIGHT 0 conversion J60 IkBa NFkB N
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa NFkB N
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J49 XIAP mRNA
type: physicalEntityParticipant
PHYSICAL-ENTITY: XIAP mRNA
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

P55212
type: unificationXref
ID: P55212
DB: UniProt Knowledgebase

LEFT 0 conversion J56 NFkB
type: physicalEntityParticipant
PHYSICAL-ENTITY: NFkB
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion J61 IkBa NFkB N
type: physicalEntityParticipant
PHYSICAL-ENTITY: IkBa NFkB N
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

datasource 1
type: dataSource
XREF: MODEL1112210000
NAME: BioModels Database

RIGHT 0 conversion J79 Casp3
type: physicalEntityParticipant
PHYSICAL-ENTITY: Casp3
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

P21580
type: unificationXref
ID: P21580
DB: UniProt Knowledgebase

LEFT 2 conversion J20 TNF TNFR TRADD
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNF TNFR TRADD
CELLULAR-LOCATION: cytoplasm
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion J18 TNF TNFR E
type: physicalEntityParticipant
PHYSICAL-ENTITY: TNF TNFR E
CELLULAR-LOCATION: extracellular
STOICHIOMETRIC-COEFFICIENT: 1.0