Figure 3d of the reference publication has been reproduced here. Xi and Xj denote the expression of pro-endocrine transcription factor Ngn3 (neurogenin-3) in cells i and j, respectively. Yi and Yj denote the expression of transcription factor Ptf1a (Pancreas-specific transcription factor 1 subunit alpha) in cells i and j, respectively.



The model was simulated using Copasi v4.8 (Build 35). The plot was generated using Gnuplot.