RIGHT 0 conversion reaction E2F
type: physicalEntityParticipant
PHYSICAL-ENTITY: E2F
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 14 CycD
type: physicalEntityParticipant
PHYSICAL-ENTITY: CycD
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 12 Myc
type: physicalEntityParticipant
PHYSICAL-ENTITY: Myc
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

Q01094
type: unificationXref
ID: Q01094
DB: UniProt Knowledgebase

compartment
type: openControlledVocabulary
XREF: C12958
TERM: cell

LEFT 0 conversion reaction 9 miR449
type: physicalEntityParticipant
PHYSICAL-ENTITY: miR449
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

conversion reaction 5
type: complexAssembly
LEFT: LEFT 0 conversion reaction 5 E2F
LEFT: LEFT 1 conversion reaction 5 RB
SPONTANEOUS: L_R
RIGHT: RIGHT 0 conversion reaction 5 RE

LEFT 0 conversion reaction 8 miR449
type: physicalEntityParticipant
PHYSICAL-ENTITY: miR449
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

conversion reaction 9
type: complexAssembly
LEFT: LEFT 1 conversion reaction 9 CycD
LEFT: LEFT 0 conversion reaction 9 miR449
SPONTANEOUS: R_L

RIGHT 1 conversion reaction 3 PRB
type: physicalEntityParticipant
PHYSICAL-ENTITY: PRB
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 21 PRB
type: physicalEntityParticipant
PHYSICAL-ENTITY: PRB
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 20 RB
type: physicalEntityParticipant
PHYSICAL-ENTITY: RB
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

conversion reaction 2
type: complexAssembly
LEFT: LEFT 0 conversion reaction 2 RE
SPONTANEOUS: R_L
RIGHT: RIGHT 0 conversion reaction 2 E2F
RIGHT: RIGHT 1 conversion reaction 2 PRB

conversion reaction 3
type: complexAssembly
LEFT: LEFT 0 conversion reaction 3 RE
SPONTANEOUS: R_L
RIGHT: RIGHT 0 conversion reaction 3 E2F
RIGHT: RIGHT 1 conversion reaction 3 PRB

BIOMD0000000318
type: unificationXref
ID: BIOMD0000000318
DB: BioModels Database

RIGHT 0 conversion reaction 16 CycE
type: physicalEntityParticipant
PHYSICAL-ENTITY: CycE
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 13 CycD
type: physicalEntityParticipant
PHYSICAL-ENTITY: CycD
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 3 E2F
type: physicalEntityParticipant
PHYSICAL-ENTITY: E2F
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

Yan2014 Rb E2F pathway dynamics with miR449
type: pathway
XREF: GO:0007049
XREF: MODEL1811080001
XREF: BIOMD0000000720
XREF: BIOMD0000000318
XREF: journal.pone.0043908
XREF: http://identifiers.org/pubmed/23028477
XREF: MAMO_0000046
PATHWAY-COMPONENTS: conversion reaction 19
PATHWAY-COMPONENTS: conversion reaction 13
PATHWAY-COMPONENTS: conversion reaction 10
PATHWAY-COMPONENTS: conversion reaction 1
PATHWAY-COMPONENTS: conversion reaction 9
PATHWAY-COMPONENTS: conversion reaction 18
PATHWAY-COMPONENTS: conversion reaction 5
PATHWAY-COMPONENTS: conversion reaction 6
PATHWAY-COMPONENTS: conversion reaction 3
PATHWAY-COMPONENTS: conversion reaction 7
PATHWAY-COMPONENTS: conversion reaction 2
PATHWAY-COMPONENTS: conversion reaction 8
PATHWAY-COMPONENTS: conversion reaction 4
PATHWAY-COMPONENTS: conversion reaction
PATHWAY-COMPONENTS: conversion reaction 11
PATHWAY-COMPONENTS: conversion reaction 12
PATHWAY-COMPONENTS: conversion reaction 24
PATHWAY-COMPONENTS: conversion reaction 22
PATHWAY-COMPONENTS: conversion reaction 23
PATHWAY-COMPONENTS: conversion reaction 20
PATHWAY-COMPONENTS: conversion reaction 21
PATHWAY-COMPONENTS: conversion reaction 16
PATHWAY-COMPONENTS: conversion reaction 17
PATHWAY-COMPONENTS: conversion reaction 14
PATHWAY-COMPONENTS: conversion reaction 15
COMMENT: This BioPAX Level2 file was automatically generated on Apr 8, 2022 by SBML2BioPAX-3.1, BioModels.net, EMBL-EBI.
COMMENT: The original model, 'Yan2014___Rb_E2F_pathway_dynamics_with_miR449', was published in BioModels Database (http://www.ebi.ac.uk/biomodels/).
ORGANISM: biosource 2
DATA-SOURCE: datasource 2
DATA-SOURCE: datasource 1

GO:0007049
type: unificationXref
ID: GO:0007049
DB: Gene Ontology

http://identifiers.org/taxonomy/40674
type: unificationXref
ID: 40674
DB: Taxonomy

P24941
type: unificationXref
ID: P24941
DB: UniProt Knowledgebase

LEFT 0 conversion reaction 10 miR449
type: physicalEntityParticipant
PHYSICAL-ENTITY: miR449
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

C20424
type: unificationXref
ID: C20424

P24385
type: unificationXref
ID: P24385
DB: UniProt Knowledgebase

RIGHT 0 conversion reaction 22 PRB
type: physicalEntityParticipant
PHYSICAL-ENTITY: PRB
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 15 CycD
type: physicalEntityParticipant
PHYSICAL-ENTITY: CycD
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

C1897
type: unificationXref
ID: C1897

RIGHT 0 conversion reaction 18 RB
type: physicalEntityParticipant
PHYSICAL-ENTITY: RB
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 6 miR449
type: physicalEntityParticipant
PHYSICAL-ENTITY: miR449
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 22 RB
type: physicalEntityParticipant
PHYSICAL-ENTITY: RB
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 5 E2F
type: physicalEntityParticipant
PHYSICAL-ENTITY: E2F
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion reaction 9 CycD
type: physicalEntityParticipant
PHYSICAL-ENTITY: CycD
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 3 RE
type: physicalEntityParticipant
PHYSICAL-ENTITY: RE
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 1 E2F
type: physicalEntityParticipant
PHYSICAL-ENTITY: E2F
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 19 PRB
type: physicalEntityParticipant
PHYSICAL-ENTITY: PRB
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

conversion reaction 17
type: complexAssembly
LEFT: LEFT 0 conversion reaction 17 CycE
SPONTANEOUS: R_L

conversion reaction 16
type: complexAssembly
SPONTANEOUS: L_R
RIGHT: RIGHT 0 conversion reaction 16 CycE

conversion reaction 15
type: complexAssembly
LEFT: LEFT 0 conversion reaction 15 CycD
SPONTANEOUS: R_L

LEFT 0 conversion reaction 21 RB
type: physicalEntityParticipant
PHYSICAL-ENTITY: RB
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

conversion reaction 14
type: complexAssembly
SPONTANEOUS: L_R
RIGHT: RIGHT 0 conversion reaction 14 CycD

P30281
type: unificationXref
ID: P30281
DB: UniProt Knowledgebase

conversion reaction 13
type: complexAssembly
SPONTANEOUS: L_R
RIGHT: RIGHT 0 conversion reaction 13 CycD

conversion reaction 10
type: complexAssembly
LEFT: LEFT 1 conversion reaction 10 CycE
LEFT: LEFT 0 conversion reaction 10 miR449
SPONTANEOUS: R_L

P30279
type: unificationXref
ID: P30279
DB: UniProt Knowledgebase

MAMO_0000046
type: unificationXref
ID: MAMO_0000046
DB: Mathematical Modelling Ontology

LEFT 0 conversion reaction 24 RE
type: physicalEntityParticipant
PHYSICAL-ENTITY: RE
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 1 conversion reaction 2 PRB
type: physicalEntityParticipant
PHYSICAL-ENTITY: PRB
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 5 RE
type: physicalEntityParticipant
PHYSICAL-ENTITY: RE
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

conversion reaction 24
type: complexAssembly
LEFT: LEFT 0 conversion reaction 24 RE
SPONTANEOUS: R_L

LEFT 1 conversion reaction 10 CycE
type: physicalEntityParticipant
PHYSICAL-ENTITY: CycE
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

Q00534
type: unificationXref
ID: Q00534
DB: UniProt Knowledgebase

LEFT 0 conversion reaction 17 CycE
type: physicalEntityParticipant
PHYSICAL-ENTITY: CycE
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

P11802
type: unificationXref
ID: P11802
DB: UniProt Knowledgebase

RIGHT 0 conversion reaction 19 RB
type: physicalEntityParticipant
PHYSICAL-ENTITY: RB
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

MIMAT0001541
type: unificationXref
ID: MIMAT0001541

LEFT 0 conversion reaction 23 PRB
type: physicalEntityParticipant
PHYSICAL-ENTITY: PRB
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

P01106
type: unificationXref
ID: P01106
DB: UniProt Knowledgebase

LEFT 1 conversion reaction 5 RB
type: physicalEntityParticipant
PHYSICAL-ENTITY: RB
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

P24864
type: unificationXref
ID: P24864
DB: UniProt Knowledgebase

RIGHT 0 conversion reaction 11 Myc
type: physicalEntityParticipant
PHYSICAL-ENTITY: Myc
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 2 RE
type: physicalEntityParticipant
PHYSICAL-ENTITY: RE
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

http://identifiers.org/pubmed/23028477
type: publicationXref
ID: 23028477
DB: PubMed

BIOMD0000000720
type: unificationXref
ID: BIOMD0000000720
DB: BioModels Database

datasource 2
type: dataSource
XREF: BIOMD0000000720
NAME: BioModels Database

LEFT 0 conversion reaction 7 miR449
type: physicalEntityParticipant
PHYSICAL-ENTITY: miR449
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

C12958
type: unificationXref
ID: C12958
DB: NCIt

P06400
type: unificationXref
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DB: UniProt Knowledgebase

journal.pone.0043908
type: publicationXref
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DB: DOI

LEFT 1 conversion reaction 8 Myc
type: physicalEntityParticipant
PHYSICAL-ENTITY: Myc
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

MODEL1811080001
type: unificationXref
ID: MODEL1811080001
DB: BioModels Database

datasource 1
type: dataSource
XREF: MODEL1811080001
NAME: BioModels Database

RIGHT 0 conversion reaction 2 E2F
type: physicalEntityParticipant
PHYSICAL-ENTITY: E2F
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 4 E2F
type: physicalEntityParticipant
PHYSICAL-ENTITY: E2F
CELLULAR-LOCATION: compartment
STOICHIOMETRIC-COEFFICIENT: 1.0