Its a mathematical model depicting CML (chronic myelogenous leukemia) interaction with T cells and impact of T cell activations on CML progression over time.

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v v

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Dn Tn Kn C n Dn Tn Kn Tn C C n

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An Kn Tn C n Ae Te An Kn Tn C C n Ae Te C C n

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De Te gammaE C De Te gammaE C Te

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Rc C Cmax Rc C Cmax C

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Dc C gammaC Te Dc C gammaC C Te

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TumorMicroenvr Constant_flux__irreversible Sn

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TumorMicroenvr naive_tcells_degradation Dn naive_Tcells Kn tumor_cells n

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TumorMicroenvr eff_tcells_production An Kn naive_Tcells tumor_cells n Ae eff_Tcells

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TumorMicroenvr eff_tcells_degradation De eff_Tcells gamma_E tumor_cells

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TumorMicroenvr Tumor_growth_equation Rc tumor_cells Cmax

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TumorMicroenvr Tumor_killing_equation Dc tumor_cells gamma_C eff_Tcells