x
type: PhysicalEntity
member physical entity: x
cellular location: Pancreatic tumor

PSC growth
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion PSC growth y STOICHIOMETRY
xref: GO:0008283
right: y

GO:0002418
type: UnificationXref
id: GO:0002418
db: Gene Ontology

BTO:0000988
type: UnificationXref
id: BTO:0000988
db: Brenda Tissue Ontology

CL:0002410
type: UnificationXref
id: CL:0002410

z
type: PhysicalEntity
member physical entity: z
cellular location: Pancreatic tumor

http://identifiers.org/taxonomy/9606
type: UnificationXref
id: 9606
db: Taxonomy

C107531
type: UnificationXref
id: C107531

GO:0008283
type: UnificationXref
id: GO:0008283
db: Gene Ontology

PSC activation by tp cytokine
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion PSC activation by tp cytokine y STOICHIOMETRY
xref: GO:0008283
right: y

RIGHT 0 conversion PSC growth y STOICHIOMETRY
type: Stoichiometry
physical entity: y
stoichiometric coefficient: 1.0

w
type: PhysicalEntity
member physical entity: w
cellular location: Pancreatic tumor

LEFT 0 conversion PSC death y STOICHIOMETRY
type: Stoichiometry
physical entity: y
stoichiometric coefficient: 1.0

BIOMD0000000744
type: UnificationXref
id: BIOMD0000000744
db: BioModels Database

y
type: PhysicalEntity
member physical entity: y
cellular location: Pancreatic tumor

effector death
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion effector death z STOICHIOMETRY
xref: GO:0008219
left: z

MAMO_0000046
type: UnificationXref
id: MAMO_0000046
db: Mathematical Modelling Ontology

RIGHT 0 conversion PSC activation by tp cytokine y STOICHIOMETRY
type: Stoichiometry
physical entity: y
stoichiometric coefficient: 1.0

MODEL1907050003
type: UnificationXref
id: MODEL1907050003
db: BioModels Database

y
type: PhysicalEntity
member physical entity: y
cellular location: Pancreatic tumor

C12536
type: UnificationXref
id: C12536

effector production
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion effector production z STOICHIOMETRY
xref: GO:0046651
right: z

tp cytokine production
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion tp cytokine production w STOICHIOMETRY
xref: GO:0001816
right: w

RIGHT 0 conversion PCC growth x STOICHIOMETRY
type: Stoichiometry
physical entity: x
stoichiometric coefficient: 1.0

LEFT 0 conversion effector death z STOICHIOMETRY
type: Stoichiometry
physical entity: z
stoichiometric coefficient: 1.0

http://identifiers.org/efo/0002618
type: UnificationXref
id: 0002618
db: Experimental Factor Ontology

RIGHT 0 conversion PCC activation by PSC x STOICHIOMETRY
type: Stoichiometry
physical entity: x
stoichiometric coefficient: 1.0

w
type: PhysicalEntity
member physical entity: w
cellular location: Pancreatic tumor

C12542
type: UnificationXref
id: C12542

effector prolif.
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion effector prolif z STOICHIOMETRY
xref: GO:0046651
right: z

GO:0001816
type: UnificationXref
id: GO:0001816
db: Gene Ontology

PCC growth
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion PCC growth x STOICHIOMETRY
xref: GO:0008283
right: x

y
type: PhysicalEntity
member physical entity: y
cellular location: Pancreatic tumor

PSC death
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion PSC death y STOICHIOMETRY
xref: GO:0008219
left: y

GO:0046651
type: UnificationXref
id: GO:0046651
db: Gene Ontology

Pancreatic tumor
type: CellularLocationVocabulary
xref: BTO:0000988
xref: C94498

PCC death
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion PCC death x STOICHIOMETRY
xref: GO:0008219
left: x

ts decay
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion ts decay v STOICHIOMETRY
xref: C40678
left: v

GO:0008219
type: UnificationXref
id: GO:0008219
db: Gene Ontology

v
type: PhysicalEntity
member physical entity: v
cellular location: Pancreatic tumor

C40678
type: UnificationXref
id: C40678
db: NCIt

ts production
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion ts production v STOICHIOMETRY
xref: GO:0001816
right: v

LEFT 0 conversion ts decay v STOICHIOMETRY
type: Stoichiometry
physical entity: v
stoichiometric coefficient: 1.0

z
type: PhysicalEntity
member physical entity: z
cellular location: Pancreatic tumor

RIGHT 0 conversion tp stimulation by PSC w STOICHIOMETRY
type: Stoichiometry
physical entity: w
stoichiometric coefficient: 1.0

CL:0001064
type: UnificationXref
id: CL:0001064

C94498
type: UnificationXref
id: C94498
db: NCIt

tp decay
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion tp decay w STOICHIOMETRY
xref: C40678
left: w

w
type: PhysicalEntity
member physical entity: w
cellular location: Pancreatic tumor

RIGHT 0 conversion tp cytokine production w STOICHIOMETRY
type: Stoichiometry
physical entity: w
stoichiometric coefficient: 1.0

Hu2019 Pancreatic cancer dynamics
type: Pathway
pathway component: PCC activation by PSC
pathway component: PCC death
pathway component: PSC growth
pathway component: effector production
pathway component: tp cytokine production
pathway component: ts decay
pathway component: ts production
pathway component: tp stimulation by PSC
pathway component: PSC activation by tp cytokine
pathway component: tp decay
pathway component: effector prolif.
pathway component: PCC growth
pathway component: effector death
pathway component: PSC death
xref: http://identifiers.org/efo/0002618
xref: GO:0002418
xref: MODEL1907050003
xref: BTO:0000988
xref: http://identifiers.org/pubmed/30843136
xref: BIOMD0000000744
xref: MAMO_0000046
organism: biosource 1
comment: This BioPAX Level3 file was automatically generated on Apr 8, 2022 by SBML2BioPAX-3.1, BioModels.net, EMBL-EBI.
comment: The original model, 'Hu2019___Pancreatic_cancer_dynamics', was published in BioModels Database (http://www.ebi.ac.uk/biomodels/).
data source: BioModels Database

BioModels Database
type: Provenance
xref: BIOMD0000000744

PCC activation by PSC
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion PCC activation by PSC x STOICHIOMETRY
xref: GO:0008283
right: x

x
type: PhysicalEntity
member physical entity: x
cellular location: Pancreatic tumor

RIGHT 0 conversion ts production v STOICHIOMETRY
type: Stoichiometry
physical entity: v
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/30843136
type: PublicationXref
id: 30843136
db: PubMed

RIGHT 0 conversion effector prolif z STOICHIOMETRY
type: Stoichiometry
physical entity: z
stoichiometric coefficient: 1.0

RIGHT 0 conversion effector production z STOICHIOMETRY
type: Stoichiometry
physical entity: z
stoichiometric coefficient: 1.0

LEFT 0 conversion tp decay w STOICHIOMETRY
type: Stoichiometry
physical entity: w
stoichiometric coefficient: 1.0

C12917
type: UnificationXref
id: C12917

tp stimulation by PSC
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion tp stimulation by PSC w STOICHIOMETRY
xref: GO:0001816
right: w

C20464
type: UnificationXref
id: C20464

BioModels Database
type: Provenance
xref: MODEL1907050003

v
type: PhysicalEntity
member physical entity: v
cellular location: Pancreatic tumor

v
type: PhysicalEntity
xref: C20464

w
type: PhysicalEntity
xref: C20464

z
type: PhysicalEntity
member physical entity: z
cellular location: Pancreatic tumor

x
type: PhysicalEntity
xref: CL:0001064
xref: C12917

LEFT 0 conversion PCC death x STOICHIOMETRY
type: Stoichiometry
physical entity: x
stoichiometric coefficient: 1.0

y
type: PhysicalEntity
xref: CL:0002410
xref: C107531

x
type: PhysicalEntity
member physical entity: x
cellular location: Pancreatic tumor

z
type: PhysicalEntity
xref: C12536
xref: C12542