LEFT 0 conversion reaction 21 pERKn
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERKn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion reaction 20 STYXn
type: physicalEntityParticipant
PHYSICAL-ENTITY: STYXn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

Q13115
type: unificationXref
ID: Q13115
DB: UniProt Knowledgebase

RIGHT 1 conversion reaction 13 DUSPn
type: physicalEntityParticipant
PHYSICAL-ENTITY: DUSPn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 10 pERK DUSPc
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERK DUSPc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 22 ppERKn
type: physicalEntityParticipant
PHYSICAL-ENTITY: ppERKn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 14 pERKn
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERKn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 2 pERKc
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERKc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

GO:0070372
type: unificationXref
ID: GO:0070372
DB: Gene Ontology

http://identifiers.org/pubmed/23847209
type: publicationXref
ID: 23847209
DB: PubMed

RIGHT 0 conversion reaction 11 ERKc
type: physicalEntityParticipant
PHYSICAL-ENTITY: ERKc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion reaction 12 DUSPn
type: physicalEntityParticipant
PHYSICAL-ENTITY: DUSPn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

conversion reaction 2
type: complexAssembly
LEFT: LEFT 0 conversion reaction 2 ERK ppMEKc
SPONTANEOUS: R_L
RIGHT: RIGHT 0 conversion reaction 2 pERKc

conversion reaction 1
type: complexAssembly
LEFT: LEFT 0 conversion reaction 1 ERKc
SPONTANEOUS: L_R
RIGHT: RIGHT 0 conversion reaction 1 ERK ppMEKc

conversion reaction 4
type: complexAssembly
LEFT: LEFT 0 conversion reaction 4 pERK ppMEKc
SPONTANEOUS: R_L
RIGHT: RIGHT 0 conversion reaction 4 ppERKc

conversion reaction 3
type: complexAssembly
LEFT: LEFT 0 conversion reaction 3 pERKc
SPONTANEOUS: L_R
RIGHT: RIGHT 0 conversion reaction 3 pERK ppMEKc

LEFT 0 conversion reaction 7 ppERKc
type: physicalEntityParticipant
PHYSICAL-ENTITY: ppERKc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

Q02750
type: unificationXref
ID: Q02750
DB: UniProt Knowledgebase

BIOMD0000000557
type: unificationXref
ID: BIOMD0000000557
DB: BioModels Database

LEFT 0 conversion reaction 1 ERKc
type: physicalEntityParticipant
PHYSICAL-ENTITY: ERKc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 13 ppERK DUSPn
type: physicalEntityParticipant
PHYSICAL-ENTITY: ppERK DUSPn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

GO:0005829
type: unificationXref
ID: GO:0005829
DB: Gene Ontology

RIGHT 0 conversion reaction 22 ppERK STYXn
type: physicalEntityParticipant
PHYSICAL-ENTITY: ppERK STYXn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 20 ERKn
type: physicalEntityParticipant
PHYSICAL-ENTITY: ERKn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 1 conversion reaction 11 DUSPc
type: physicalEntityParticipant
PHYSICAL-ENTITY: DUSPc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 3 pERKc
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERKc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 5 ERKn
type: physicalEntityParticipant
PHYSICAL-ENTITY: ERKn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 1 conversion reaction 15 DUSPn
type: physicalEntityParticipant
PHYSICAL-ENTITY: DUSPn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 14 pERK DUSPn
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERK DUSPn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 12 ppERK DUSPn
type: physicalEntityParticipant
PHYSICAL-ENTITY: ppERK DUSPn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 10 pERKc
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERKc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 19 DUSPn
type: physicalEntityParticipant
PHYSICAL-ENTITY: DUSPn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

cytosol
type: openControlledVocabulary
XREF: GO:0005829
TERM: cytosol

LEFT 0 conversion reaction 12 ppERKn
type: physicalEntityParticipant
PHYSICAL-ENTITY: ppERKn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

nucleus
type: openControlledVocabulary
XREF: GO:0005634
TERM: nucleus

LEFT 0 conversion reaction 2 ERK ppMEKc
type: physicalEntityParticipant
PHYSICAL-ENTITY: ERK ppMEKc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 4 ppERKc
type: physicalEntityParticipant
PHYSICAL-ENTITY: ppERKc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 6 pERKn
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERKn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 15 ERKn
type: physicalEntityParticipant
PHYSICAL-ENTITY: ERKn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 8 ppERKc
type: physicalEntityParticipant
PHYSICAL-ENTITY: ppERKc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 18 DUSPn
type: physicalEntityParticipant
PHYSICAL-ENTITY: DUSPn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion reaction 10 DUSPc
type: physicalEntityParticipant
PHYSICAL-ENTITY: DUSPc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

P27361
type: unificationXref
ID: P27361
DB: UniProt Knowledgebase

RIGHT 1 conversion reaction 9 DUSPc
type: physicalEntityParticipant
PHYSICAL-ENTITY: DUSPc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 13 pERKn
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERKn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 21 pERK STYXn
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERK STYXn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 9 ppERK DUSPc
type: physicalEntityParticipant
PHYSICAL-ENTITY: ppERK DUSPc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 20 ERK STYXn
type: physicalEntityParticipant
PHYSICAL-ENTITY: ERK STYXn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

conversion reaction 15
type: complexAssembly
LEFT: LEFT 0 conversion reaction 15 pERK DUSPn
SPONTANEOUS: R_L
RIGHT: RIGHT 1 conversion reaction 15 DUSPn
RIGHT: RIGHT 0 conversion reaction 15 ERKn

conversion reaction 14
type: complexAssembly
LEFT: LEFT 1 conversion reaction 14 DUSPn
LEFT: LEFT 0 conversion reaction 14 pERKn
SPONTANEOUS: L_R
RIGHT: RIGHT 0 conversion reaction 14 pERK DUSPn

conversion reaction 13
type: complexAssembly
LEFT: LEFT 0 conversion reaction 13 ppERK DUSPn
SPONTANEOUS: R_L
RIGHT: RIGHT 0 conversion reaction 13 pERKn
RIGHT: RIGHT 1 conversion reaction 13 DUSPn

http://identifiers.org/taxonomy/9606
type: unificationXref
ID: 9606
DB: Taxonomy

conversion reaction 12
type: complexAssembly
LEFT: LEFT 0 conversion reaction 12 ppERKn
LEFT: LEFT 1 conversion reaction 12 DUSPn
SPONTANEOUS: L_R
RIGHT: RIGHT 0 conversion reaction 12 ppERK DUSPn

LEFT 0 conversion reaction 5 ERKc
type: physicalEntityParticipant
PHYSICAL-ENTITY: ERKc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 15 pERK DUSPn
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERK DUSPn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion reaction 14 DUSPn
type: physicalEntityParticipant
PHYSICAL-ENTITY: DUSPn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 1 ERK ppMEKc
type: physicalEntityParticipant
PHYSICAL-ENTITY: ERK ppMEKc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

Q8WUJ0
type: unificationXref
ID: Q8WUJ0
DB: UniProt Knowledgebase

MODEL1410300001
type: pathway
XREF: http://identifiers.org/pubmed/23847209
XREF: BIOMD0000000557
XREF: BTO:0000567
XREF: MODEL1410300001
XREF: GO:0070372
PATHWAY-COMPONENTS: conversion reaction 12
PATHWAY-COMPONENTS: conversion reaction 19
PATHWAY-COMPONENTS: conversion reaction 13
PATHWAY-COMPONENTS: conversion reaction 17
PATHWAY-COMPONENTS: conversion reaction 21
PATHWAY-COMPONENTS: conversion reaction 18
PATHWAY-COMPONENTS: conversion reaction 22
PATHWAY-COMPONENTS: conversion reaction 20
PATHWAY-COMPONENTS: conversion reaction 4
PATHWAY-COMPONENTS: conversion reaction 3
PATHWAY-COMPONENTS: conversion reaction 2
PATHWAY-COMPONENTS: conversion reaction 8
PATHWAY-COMPONENTS: conversion reaction 1
PATHWAY-COMPONENTS: conversion reaction 9
PATHWAY-COMPONENTS: conversion reaction 11
PATHWAY-COMPONENTS: conversion reaction 10
PATHWAY-COMPONENTS: conversion reaction 6
PATHWAY-COMPONENTS: conversion reaction 7
PATHWAY-COMPONENTS: conversion reaction 16
PATHWAY-COMPONENTS: conversion reaction 14
PATHWAY-COMPONENTS: conversion reaction 5
PATHWAY-COMPONENTS: conversion reaction 15
COMMENT: The original model, 'MODEL1410300001', was published in BioModels Database (http://www.ebi.ac.uk/biomodels/).
COMMENT: This BioPAX Level2 file was automatically generated on 23-Jun-2017 by SBML2BioPAX-3.1, BioModels.net, EMBL-EBI.
ORGANISM: biosource 1
DATA-SOURCE: datasource 2
DATA-SOURCE: datasource 1

RIGHT 0 conversion reaction 7 ppERKn
type: physicalEntityParticipant
PHYSICAL-ENTITY: ppERKn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

conversion reaction 20
type: complexAssembly
LEFT: LEFT 0 conversion reaction 20 ERKn
LEFT: LEFT 1 conversion reaction 20 STYXn
SPONTANEOUS: L_R
RIGHT: RIGHT 0 conversion reaction 20 ERK STYXn

MODEL1410300001
type: unificationXref
ID: MODEL1410300001
DB: BioModels Database

conversion reaction 22
type: complexAssembly
LEFT: LEFT 1 conversion reaction 22 STYXn
LEFT: LEFT 0 conversion reaction 22 ppERKn
SPONTANEOUS: L_R
RIGHT: RIGHT 0 conversion reaction 22 ppERK STYXn

conversion reaction 21
type: complexAssembly
LEFT: LEFT 0 conversion reaction 21 pERKn
LEFT: LEFT 1 conversion reaction 21 STYXn
SPONTANEOUS: L_R
RIGHT: RIGHT 0 conversion reaction 21 pERK STYXn

RIGHT 0 conversion reaction 8 ppERK DUSPc
type: physicalEntityParticipant
PHYSICAL-ENTITY: ppERK DUSPc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 11 pERK DUSPc
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERK DUSPc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 16 duspn
type: physicalEntityParticipant
PHYSICAL-ENTITY: duspn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

BTO:0000567
type: unificationXref
ID: BTO:0000567
DB: Brenda Tissue Ontology

LEFT 0 conversion reaction 6 pERKc
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERKc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion reaction 22 STYXn
type: physicalEntityParticipant
PHYSICAL-ENTITY: STYXn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 0 conversion reaction 17 duspn
type: physicalEntityParticipant
PHYSICAL-ENTITY: duspn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

datasource 2
type: dataSource
XREF: BIOMD0000000557
NAME: BioModels Database

LEFT 1 conversion reaction 21 STYXn
type: physicalEntityParticipant
PHYSICAL-ENTITY: STYXn
CELLULAR-LOCATION: nucleus
STOICHIOMETRIC-COEFFICIENT: 1.0

GO:0005634
type: unificationXref
ID: GO:0005634
DB: Gene Ontology

datasource 1
type: dataSource
XREF: MODEL1410300001
NAME: BioModels Database

LEFT 0 conversion reaction 4 pERK ppMEKc
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERK ppMEKc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

LEFT 1 conversion reaction 8 DUSPc
type: physicalEntityParticipant
PHYSICAL-ENTITY: DUSPc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 9 pERKc
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERKc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0

RIGHT 0 conversion reaction 3 pERK ppMEKc
type: physicalEntityParticipant
PHYSICAL-ENTITY: pERK ppMEKc
CELLULAR-LOCATION: cytosol
STOICHIOMETRIC-COEFFICIENT: 1.0