myTHFGlu
type: PhysicalEntity
member physical entity: myTHFGlu
cellular location: Single celled micro-organism

Gln
type: SmallMolecule
xref: C00064

myTHFGlu
type: SmallMolecule
xref: C00143

THFGlu
type: PhysicalEntity
member physical entity: THFGlu
cellular location: Single celled micro-organism

LEFT 1 conversion R24 ADP STOICHIOMETRY
type: Stoichiometry
physical entity: ADP
stoichiometric coefficient: 1.0

Glu
type: SmallMolecule
xref: C00025

Gly
type: SmallMolecule
xref: C00037

Single celled micro-organism
type: CellularLocationVocabulary

RIGHT 1 conversion R27 Pi STOICHIOMETRY
type: Stoichiometry
physical entity: Pi
stoichiometric coefficient: 1.0

C02051
type: UnificationXref
id: C02051
db: KEGG Compound

AHMDHP
type: PhysicalEntity
member physical entity: AHMDHP
cellular location: Single celled micro-organism

RIGHT 0 conversion R22 meTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: meTHFGlu
stoichiometric coefficient: 1.0

LEFT 1 conversion R14 Glu STOICHIOMETRY
type: Stoichiometry
physical entity: Glu
stoichiometric coefficient: 1.0

RIGHT 0 conversion R11 AHMDHP STOICHIOMETRY
type: Stoichiometry
physical entity: AHMDHP
stoichiometric coefficient: 1.0

LEFT 0 conversion R1 PEP STOICHIOMETRY
type: Stoichiometry
physical entity: PEP
stoichiometric coefficient: 1.0

Pi
type: PhysicalEntity
member physical entity: Pi
cellular location: Single celled micro-organism

Pyr
type: PhysicalEntity
member physical entity: Pyr
cellular location: Single celled micro-organism

LEFT 0 conversion R18c THFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: THFGlu
stoichiometric coefficient: 1.0

Ser
type: SmallMolecule
xref: C00065

DHF
type: SmallMolecule
xref: C00415

LEFT 1 conversion R16 Glu STOICHIOMETRY
type: Stoichiometry
physical entity: Glu
stoichiometric coefficient: 1.0

R01826
type: UnificationXref
id: R01826
db: KEGG Reaction

R11 - Dihydroneopterin aldolase
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R11 DHNTP STOICHIOMETRY
participant stoichiometry: RIGHT 2 conversion R11 Pi STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R11 HAD STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R11 AHMDHP STOICHIOMETRY
xref: R03504
right: AHMDHP
right: HAD
right: Pi
left: DHNTP

R10 - GTP 7,8,9-dihydrolase (GTP cyclohydrolase I)
type: BiochemicalReaction
participant stoichiometry: RIGHT 1 conversion R10 Formyl STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R10 DHNTP STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R10 GTP STOICHIOMETRY
xref: R00424
right: DHNTP
right: Formyl
left: GTP

NADPH
type: PhysicalEntity
member physical entity: NADPH
cellular location: Single celled micro-organism

R13 - Dihydropteroate synthase
type: BiochemicalReaction
participant stoichiometry: RIGHT 1 conversion R13 Pi STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R13 AHMDPP STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R13 DHP STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R13 pABA STOICHIOMETRY
xref: R03067
right: Pi
right: DHP
left: AHMDPP
left: pABA

mtRNA
type: Rna
xref: C02430

R12 - 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
type: BiochemicalReaction
participant stoichiometry: LEFT 1 conversion R12 ATP STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R12 AHMDPP STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R12 AMP STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R12 AHMDHP STOICHIOMETRY
xref: R03503
right: AHMDPP
right: AMP
left: ATP
left: AHMDHP

DHQ
type: SmallMolecule
xref: C00944

R15 - Dihydrofolate reductase
type: BiochemicalReaction
participant stoichiometry: RIGHT 1 conversion R15 NADP STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R15 THF STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R15 NADPH STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R15 DHF STOICHIOMETRY
xref: R00939
right: THF
right: NADP
left: DHF
left: NADPH

DHP
type: SmallMolecule
xref: C00921

R14 - 7,8-Dihydrofolate synthase
type: BiochemicalReaction
participant stoichiometry: LEFT 2 conversion R14 ATP STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R14 ADP STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R14 DHF STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R14 DHP STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R14 Glu STOICHIOMETRY
participant stoichiometry: RIGHT 2 conversion R14 Pi STOICHIOMETRY
xref: R02237
right: DHF
right: ADP
right: Pi
left: DHP
left: Glu
left: ATP

R17 - Serine hydroxymethyltransferase
type: BiochemicalReaction
participant stoichiometry: RIGHT 1 conversion R17 Gly STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R17 Ser STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R17 THFGlu STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R17 myTHFGlu STOICHIOMETRY
xref: R00945
right: myTHFGlu
right: Gly
left: Ser
left: THFGlu

R16 - Folylpoly-gamma-glutamate synthase
type: BiochemicalReaction
participant stoichiometry: RIGHT 2 conversion R16 Pi STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R16 THF STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R16 Glu STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R16 THFGlu STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R16 ADP STOICHIOMETRY
participant stoichiometry: LEFT 2 conversion R16 ATP STOICHIOMETRY
xref: R04241
right: THFGlu
right: ADP
right: Pi
left: ATP
left: Glu
left: THF

RIGHT 1 conversion R24 ATP STOICHIOMETRY
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

CM
type: PhysicalEntity
member physical entity: CM
cellular location: Single celled micro-organism

R19 - 5,10-Methylenetetrahydrofolate reductase
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R19 myTHFGlu STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R19 NADPH STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R19 NADP STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R19 MTHFGlu STOICHIOMETRY
xref: R01224
right: MTHFGlu
right: NADP
left: myTHFGlu
left: NADPH

THF
type: SmallMolecule
xref: C00101

fmtRNA
type: PhysicalEntity
member physical entity: fmtRNA
cellular location: Single celled micro-organism

HAD
type: PhysicalEntity
member physical entity: HAD
cellular location: Single celled micro-organism

R01714
type: UnificationXref
id: R01714
db: KEGG Reaction

R01716
type: UnificationXref
id: R01716
db: KEGG Reaction

R20 - Methionine synthase
type: BiochemicalReaction
participant stoichiometry: LEFT 1 conversion R20 Hcy STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R20 MTHFGlu STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R20 THFGlu STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R20 Met STOICHIOMETRY
xref: R00946
right: Met
right: THFGlu
left: MTHFGlu
left: Hcy

fTHFGlu
type: PhysicalEntity
member physical entity: fTHFGlu
cellular location: Single celled micro-organism

R22 - 5,10-Methylenetetrahydrofolate dehydrogenase
type: BiochemicalReaction
participant stoichiometry: RIGHT 1 conversion R22 NADPH STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R22 meTHFGlu STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R22 myTHFGlu STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R22 NADP STOICHIOMETRY
xref: R01220
right: NADPH
right: meTHFGlu
left: NADP
left: myTHFGlu

R21 - Thymidylate synthase
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R21 myTHFGlu STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R21 dUMP STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R21 DHF STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R21 dTMP STOICHIOMETRY
xref: R02101
right: dTMP
right: DHF
left: myTHFGlu
left: dUMP

CM
type: SmallMolecule
xref: C00251

R24 - 10-Formyltetrahydrofolate synthetase
type: BiochemicalReaction
participant stoichiometry: RIGHT 2 conversion R24 Formyl STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R24 THFGlu STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R24 fTHFGlu STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R24 ADP STOICHIOMETRY
participant stoichiometry: LEFT 2 conversion R24 Pi STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R24 ATP STOICHIOMETRY
xref: R00943
right: THFGlu
right: ATP
right: Formyl
left: ADP
left: Pi
left: fTHFGlu

R23 - 5,10-Methenyltetrahydrofolate cyclohydrolase
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R23 fTHFGlu STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R23 meTHFGlu STOICHIOMETRY
xref: R01655
right: fTHFGlu
left: meTHFGlu

ADP
type: PhysicalEntity
member physical entity: ADP
cellular location: Single celled micro-organism

R26 - 10-Formyltetrahydrofolate dehydrogenase
type: BiochemicalReaction
participant stoichiometry: RIGHT 2 conversion R26 NADPH STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R26 NADP STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R26 fTHFGlu STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R26 THFGlu STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R26 COTwo STOICHIOMETRY
xref: R00941
right: NADPH
right: COTwo
right: THFGlu
left: NADP
left: fTHFGlu

R25 - Methionyl-tRNA formyltransferase
type: BiochemicalReaction
participant stoichiometry: LEFT 1 conversion R25 mtRNA STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R25 fmtRNA STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R25 THFGlu STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R25 fTHFGlu STOICHIOMETRY
xref: R03940
right: fmtRNA
right: THFGlu
left: mtRNA
left: fTHFGlu

LEFT 0 conversion R28 meTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: meTHFGlu
stoichiometric coefficient: 1.0

R28 - S-Aminomethyldihydrolipoylprotein:tetrahydrofolate aminomethyltransferase (T protein)
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R28 ffTHFGlu STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R28 meTHFGlu STOICHIOMETRY
xref: R02300
right: ffTHFGlu
left: meTHFGlu

R27 - 6-Pyruvoyltetrahydropterin synthase
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R27 PTHP STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R27 DHNTP STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R27 Pi STOICHIOMETRY
xref: R04286
right: Pi
right: PTHP
left: DHNTP

R29 - 5-formyltetrahydrofolate cyclo-ligase
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R29 ADP STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R29 ATP STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R29 ffTHFGlu STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R29 Pi STOICHIOMETRY
participant stoichiometry: RIGHT 2 conversion R29 meTHFGlu STOICHIOMETRY
xref: R02301
right: ADP
right: meTHFGlu
right: Pi
left: ffTHFGlu
left: ATP

Lp
type: PhysicalEntity
member physical entity: Lp
cellular location: Single celled micro-organism

RIGHT 0 conversion R2 DHQ STOICHIOMETRY
type: Stoichiometry
physical entity: DHQ
stoichiometric coefficient: 1.0

LEFT 0 conversion R24 fTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: fTHFGlu
stoichiometric coefficient: 1.0

RIGHT 0 conversion R17 myTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: myTHFGlu
stoichiometric coefficient: 1.0

Gln
type: PhysicalEntity
member physical entity: Gln
cellular location: Single celled micro-organism

ADC
type: SmallMolecule
xref: C11355

RIGHT 0 conversion R15 THF STOICHIOMETRY
type: Stoichiometry
physical entity: THF
stoichiometric coefficient: 1.0

ATP
type: PhysicalEntity
member physical entity: ATP
cellular location: Single celled micro-organism

SKP
type: PhysicalEntity
member physical entity: SKP
cellular location: Single celled micro-organism

R03940
type: UnificationXref
id: R03940
db: KEGG Reaction

DHQ
type: PhysicalEntity
member physical entity: DHQ
cellular location: Single celled micro-organism

LEFT 0 conversion R14 DHP STOICHIOMETRY
type: Stoichiometry
physical entity: DHP
stoichiometric coefficient: 1.0

ADP
type: SmallMolecule
xref: C00008

RIGHT 2 conversion R29 meTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: meTHFGlu
stoichiometric coefficient: 1.0

DHNTP
type: PhysicalEntity
member physical entity: DHNTP
cellular location: Single celled micro-organism

RIGHT 2 conversion R16 Pi STOICHIOMETRY
type: Stoichiometry
physical entity: Pi
stoichiometric coefficient: 1.0

RIGHT 1 conversion R22 NADPH STOICHIOMETRY
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

C00073
type: UnificationXref
id: C00073
db: KEGG Compound

C00074
type: UnificationXref
id: C00074
db: KEGG Compound

RIGHT 0 conversion R18a DLp STOICHIOMETRY
type: Stoichiometry
physical entity: DLp
stoichiometric coefficient: 1.0

pABA
type: PhysicalEntity
member physical entity: pABA
cellular location: Single celled micro-organism

C01269
type: UnificationXref
id: C01269
db: KEGG Compound

C00058
type: UnificationXref
id: C00058
db: KEGG Compound

RIGHT 1 conversion R8 Glu STOICHIOMETRY
type: Stoichiometry
physical entity: Glu
stoichiometric coefficient: 1.0

EP
type: SmallMolecule
xref: C00279

RIGHT 1 conversion R5 ADP STOICHIOMETRY
type: Stoichiometry
physical entity: ADP
stoichiometric coefficient: 1.0

NADP
type: PhysicalEntity
member physical entity: NADP
cellular location: Single celled micro-organism

R01655
type: UnificationXref
id: R01655
db: KEGG Reaction

LEFT 0 conversion R11 DHNTP STOICHIOMETRY
type: Stoichiometry
physical entity: DHNTP
stoichiometric coefficient: 1.0

RIGHT 1 conversion R20 Met STOICHIOMETRY
type: Stoichiometry
physical entity: Met
stoichiometric coefficient: 1.0

C5MB00801H
type: PublicationXref
id: 10.1039/C5MB00801H
db: DOI

C00064
type: UnificationXref
id: C00064
db: KEGG Compound

C00065
type: UnificationXref
id: C00065
db: KEGG Compound

RIGHT 1 conversion R26 COTwo STOICHIOMETRY
type: Stoichiometry
physical entity: COTwo
stoichiometric coefficient: 1.0

RIGHT 1 conversion R10 Formyl STOICHIOMETRY
type: Stoichiometry
physical entity: Formyl
stoichiometric coefficient: 1.0

Pi
type: PhysicalEntity
member physical entity: Pi
cellular location: Single celled micro-organism

C03479
type: UnificationXref
id: C03479
db: KEGG Compound

NADP
type: PhysicalEntity
member physical entity: NADP
cellular location: Single celled micro-organism

RIGHT 0 conversion R18c myTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: myTHFGlu
stoichiometric coefficient: 1.0

RIGHT 2 conversion R11 Pi STOICHIOMETRY
type: Stoichiometry
physical entity: Pi
stoichiometric coefficient: 1.0

RIGHT 0 conversion R25 fmtRNA STOICHIOMETRY
type: Stoichiometry
physical entity: fmtRNA
stoichiometric coefficient: 1.0

myTHFGlu
type: PhysicalEntity
member physical entity: myTHFGlu
cellular location: Single celled micro-organism

C04691
type: UnificationXref
id: C04691
db: KEGG Compound

RIGHT 1 conversion R18b COTwo STOICHIOMETRY
type: Stoichiometry
physical entity: COTwo
stoichiometric coefficient: 1.0

R03815
type: UnificationXref
id: R03815
db: KEGG Reaction

C38809
type: UnificationXref
id: C38809
db: NCIt

THFGlu
type: PhysicalEntity
member physical entity: THFGlu
cellular location: Single celled micro-organism

R1 - Synthesis of 3-Deoxy-7-phosphoheptulonate
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R1 PEP STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R1 EP STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R1 DAHP STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R1 Pi STOICHIOMETRY
xref: R01826
right: DAHP
right: Pi
left: PEP
left: EP

DLp
type: Protein
xref: C02972

R2 - 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate phosphate-lyase (3-Dehydroquinate synthase)
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R2 DAHP STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R2 DHQ STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R2 Pi STOICHIOMETRY
xref: R03083
right: DHQ
right: Pi
left: DAHP

R3 - 3-Dehydroquinate hydro-lyase (3-Dehydroquinate dehydratase)
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R3 DHQ STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R3 DHSK STOICHIOMETRY
xref: R03084
right: DHSK
left: DHQ

R4 - Shikimate:NADP + 3-oxidoreductase (Shikimate 5-dehydrogenase)
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R4 SK STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R4 NADPH STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R4 DHSK STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R4 NADP STOICHIOMETRY
xref: R02413
right: SK
right: NADP
left: DHSK
left: NADPH

R5 - ATP:Shikimate 3-phosphotransferase (Shikimate kinase)
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R5 SKP STOICHIOMETRY
participant stoichiometry: RIGHT 2 conversion R5 Pi STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R5 ATP STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R5 ADP STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R5 SK STOICHIOMETRY
xref: R02412
right: SKP
right: Pi
right: ADP
left: ATP
left: SK

R6 - Phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase
type: BiochemicalReaction
participant stoichiometry: LEFT 1 conversion R6 PEP STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R6 SKP STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R6 Pi STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R6 CVPSK STOICHIOMETRY
xref: R03460
right: Pi
right: CVPSK
left: PEP
left: SKP

R7 - 5-O-(1-Carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate synthase)
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion R7 CM STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R7 CVPSK STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R7 Pi STOICHIOMETRY
xref: R01714
right: CM
right: Pi
left: CVPSK

R00424
type: UnificationXref
id: R00424
db: KEGG Reaction

R8 - Aminodeoxychorismate synthase
type: BiochemicalReaction
participant stoichiometry: LEFT 1 conversion R8 Gln STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R8 CM STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R8 ADC STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R8 Glu STOICHIOMETRY
xref: R01716
right: Glu
right: ADC
left: CM
left: Gln

NAD
type: SmallMolecule
xref: C00003

R9 - Aminodeoxychorismate lyase
type: BiochemicalReaction
participant stoichiometry: RIGHT 1 conversion R9 Pyr STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R9 pABA STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R9 ADC STOICHIOMETRY
xref: R05553
right: pABA
right: Pyr
left: ADC

myTHFGlu
type: PhysicalEntity
member physical entity: myTHFGlu
cellular location: Single celled micro-organism

RIGHT 0 conversion R5 SKP STOICHIOMETRY
type: Stoichiometry
physical entity: SKP
stoichiometric coefficient: 1.0

SKP
type: SmallMolecule
xref: C03175

PEP
type: SmallMolecule
xref: C00074

DHNTP
type: PhysicalEntity
member physical entity: DHNTP
cellular location: Single celled micro-organism

Pi
type: PhysicalEntity
member physical entity: Pi
cellular location: Single celled micro-organism

Pi
type: PhysicalEntity
member physical entity: Pi
cellular location: Single celled micro-organism

GTP
type: SmallMolecule
xref: C00044

C00266
type: UnificationXref
id: C00266
db: KEGG Compound

C00025
type: UnificationXref
id: C00025
db: KEGG Compound

R03503
type: UnificationXref
id: R03503
db: KEGG Reaction

R03504
type: UnificationXref
id: R03504
db: KEGG Reaction

R02412
type: UnificationXref
id: R02412
db: KEGG Reaction

R02413
type: UnificationXref
id: R02413
db: KEGG Reaction

LEFT 2 conversion R24 Pi STOICHIOMETRY
type: Stoichiometry
physical entity: Pi
stoichiometric coefficient: 1.0

THFGlu
type: SmallMolecule
xref: C03541

LEFT 1 conversion R1 EP STOICHIOMETRY
type: Stoichiometry
physical entity: EP
stoichiometric coefficient: 1.0

ffTHFGlu
type: PhysicalEntity
member physical entity: ffTHFGlu
cellular location: Single celled micro-organism

RIGHT 2 conversion R5 Pi STOICHIOMETRY
type: Stoichiometry
physical entity: Pi
stoichiometric coefficient: 1.0

LEFT 0 conversion R18a Lp STOICHIOMETRY
type: Stoichiometry
physical entity: Lp
stoichiometric coefficient: 1.0

NADP
type: PhysicalEntity
member physical entity: NADP
cellular location: Single celled micro-organism

C03541
type: UnificationXref
id: C03541
db: KEGG Compound

C00155
type: UnificationXref
id: C00155
db: KEGG Compound

C01242
type: UnificationXref
id: C01242
db: KEGG Compound

RIGHT 0 conversion R4 SK STOICHIOMETRY
type: Stoichiometry
physical entity: SK
stoichiometric coefficient: 1.0

LEFT 2 conversion R14 ATP STOICHIOMETRY
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

C00014
type: UnificationXref
id: C00014
db: KEGG Compound

DHF
type: PhysicalEntity
member physical entity: DHF
cellular location: Single celled micro-organism

R02300
type: UnificationXref
id: R02300
db: KEGG Reaction

R02301
type: UnificationXref
id: R02301
db: KEGG Reaction

RIGHT 1 conversion R6 Pi STOICHIOMETRY
type: Stoichiometry
physical entity: Pi
stoichiometric coefficient: 1.0

Pi
type: PhysicalEntity
member physical entity: Pi
cellular location: Single celled micro-organism

ADP
type: PhysicalEntity
member physical entity: ADP
cellular location: Single celled micro-organism

fTHFGlu
type: PhysicalEntity
member physical entity: fTHFGlu
cellular location: Single celled micro-organism

Gly
type: PhysicalEntity
member physical entity: Gly
cellular location: Single celled micro-organism

THFGlu
type: PhysicalEntity
member physical entity: THFGlu
cellular location: Single celled micro-organism

C00022
type: UnificationXref
id: C00022
db: KEGG Compound

C00143
type: UnificationXref
id: C00143
db: KEGG Compound

C00020
type: UnificationXref
id: C00020
db: KEGG Compound

LEFT 1 conversion R19 NADPH STOICHIOMETRY
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

fTHFGlu
type: SmallMolecule
xref: C00234

Formyl
type: PhysicalEntity
member physical entity: Formyl
cellular location: Single celled micro-organism

RIGHT 0 conversion R28 ffTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: ffTHFGlu
stoichiometric coefficient: 1.0

RIGHT 1 conversion R14 ADP STOICHIOMETRY
type: Stoichiometry
physical entity: ADP
stoichiometric coefficient: 1.0

myTHFGlu
type: PhysicalEntity
member physical entity: myTHFGlu
cellular location: Single celled micro-organism

NADH
type: SmallMolecule
xref: C00004

MTHFGlu
type: PhysicalEntity
member physical entity: MTHFGlu
cellular location: Single celled micro-organism

LEFT 1 conversion R21 dUMP STOICHIOMETRY
type: Stoichiometry
physical entity: dUMP
stoichiometric coefficient: 1.0

C03684
type: UnificationXref
id: C03684
db: KEGG Compound

C04895
type: UnificationXref
id: C04895
db: KEGG Compound

NADP
type: SmallMolecule
xref: C00006

C00279
type: UnificationXref
id: C00279
db: KEGG Compound

C00037
type: UnificationXref
id: C00037
db: KEGG Compound

CVPSK
type: PhysicalEntity
member physical entity: CVPSK
cellular location: Single celled micro-organism

meTHFGlu
type: PhysicalEntity
member physical entity: meTHFGlu
cellular location: Single celled micro-organism

meTHFGlu
type: PhysicalEntity
member physical entity: meTHFGlu
cellular location: Single celled micro-organism

LEFT 1 conversion R18c SAmDLp STOICHIOMETRY
type: Stoichiometry
physical entity: SAmDLp
stoichiometric coefficient: 1.0

NADH
type: PhysicalEntity
member physical entity: NADH
cellular location: Single celled micro-organism

NADPH
type: PhysicalEntity
member physical entity: NADPH
cellular location: Single celled micro-organism

LEFT 0 conversion R13 AHMDPP STOICHIOMETRY
type: Stoichiometry
physical entity: AHMDPP
stoichiometric coefficient: 1.0

RIGHT 1 conversion R2 Pi STOICHIOMETRY
type: Stoichiometry
physical entity: Pi
stoichiometric coefficient: 1.0

Glu
type: PhysicalEntity
member physical entity: Glu
cellular location: Single celled micro-organism

RIGHT 1 conversion R12 AMP STOICHIOMETRY
type: Stoichiometry
physical entity: AMP
stoichiometric coefficient: 1.0

AHMDPP
type: SmallMolecule
xref: C04807

RIGHT 0 conversion R13 DHP STOICHIOMETRY
type: Stoichiometry
physical entity: DHP
stoichiometric coefficient: 1.0

C00044
type: UnificationXref
id: C00044
db: KEGG Compound

C00101
type: UnificationXref
id: C00101
db: KEGG Compound

AHMDPP
type: PhysicalEntity
member physical entity: AHMDPP
cellular location: Single celled micro-organism

LEFT 0 conversion R25 fTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: fTHFGlu
stoichiometric coefficient: 1.0

R03425
type: UnificationXref
id: R03425
db: KEGG Reaction

C11355
type: UnificationXref
id: C11355
db: KEGG Compound

DHP
type: PhysicalEntity
member physical entity: DHP
cellular location: Single celled micro-organism

COTwo
type: PhysicalEntity

fTHFGlu
type: PhysicalEntity
member physical entity: fTHFGlu
cellular location: Single celled micro-organism

fmtRNA
type: Rna
xref: C03294

DHSK
type: PhysicalEntity
member physical entity: DHSK
cellular location: Single celled micro-organism

C01300
type: UnificationXref
id: C01300
db: KEGG Compound

AMP
type: SmallMolecule
xref: C00020

Lp
type: Protein
xref: C02051

C02637
type: UnificationXref
id: C02637
db: KEGG Compound

MTHFGlu
type: SmallMolecule
xref: C00440

THF
type: PhysicalEntity
member physical entity: THF
cellular location: Single celled micro-organism

Pi
type: PhysicalEntity
member physical entity: Pi
cellular location: Single celled micro-organism

R02101
type: UnificationXref
id: R02101
db: KEGG Reaction

RIGHT 1 conversion R19 NADP STOICHIOMETRY
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

LEFT 0 conversion R4 DHSK STOICHIOMETRY
type: Stoichiometry
physical entity: DHSK
stoichiometric coefficient: 1.0

RIGHT 1 conversion R15 NADP STOICHIOMETRY
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Met
type: PhysicalEntity
member physical entity: Met
cellular location: Single celled micro-organism

LEFT 1 conversion R15 NADPH STOICHIOMETRY
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Ser
type: PhysicalEntity
member physical entity: Ser
cellular location: Single celled micro-organism

RIGHT 1 conversion R21 DHF STOICHIOMETRY
type: Stoichiometry
physical entity: DHF
stoichiometric coefficient: 1.0

LEFT 0 conversion R19 myTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: myTHFGlu
stoichiometric coefficient: 1.0

LEFT 0 conversion R18b DLp STOICHIOMETRY
type: Stoichiometry
physical entity: DLp
stoichiometric coefficient: 1.0

Met
type: SmallMolecule
xref: C00073

Pi
type: PhysicalEntity
member physical entity: Pi
cellular location: Single celled micro-organism

C00004
type: UnificationXref
id: C00004
db: KEGG Compound

C00005
type: UnificationXref
id: C00005
db: KEGG Compound

SAmDLp
type: Protein
xref: C01242

C00365
type: UnificationXref
id: C00365
db: KEGG Compound

C00002
type: UnificationXref
id: C00002
db: KEGG Compound

C00003
type: UnificationXref
id: C00003
db: KEGG Compound

C00008
type: UnificationXref
id: C00008
db: KEGG Compound

C00009
type: UnificationXref
id: C00009
db: KEGG Compound

ADC
type: PhysicalEntity
member physical entity: ADC
cellular location: Single celled micro-organism

C00006
type: UnificationXref
id: C00006
db: KEGG Compound

R01220
type: UnificationXref
id: R01220
db: KEGG Reaction

Pi
type: PhysicalEntity
member physical entity: Pi
cellular location: Single celled micro-organism

R01224
type: UnificationXref
id: R01224
db: KEGG Reaction

RIGHT 2 conversion R26 NADPH STOICHIOMETRY
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Ammonia
type: PhysicalEntity
member physical entity: Ammonia
cellular location: Single celled micro-organism

LEFT 0 conversion R29 ATP STOICHIOMETRY
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

LEFT 0 conversion R16 THF STOICHIOMETRY
type: Stoichiometry
physical entity: THF
stoichiometric coefficient: 1.0

RIGHT 1 conversion R17 Gly STOICHIOMETRY
type: Stoichiometry
physical entity: Gly
stoichiometric coefficient: 1.0

mtRNA
type: PhysicalEntity
member physical entity: mtRNA
cellular location: Single celled micro-organism

LEFT 0 conversion R2 DAHP STOICHIOMETRY
type: Stoichiometry
physical entity: DAHP
stoichiometric coefficient: 1.0

ADP
type: PhysicalEntity
member physical entity: ADP
cellular location: Single celled micro-organism

DAHP
type: PhysicalEntity
member physical entity: DAHP
cellular location: Single celled micro-organism

RIGHT 1 conversion R11 HAD STOICHIOMETRY
type: Stoichiometry
physical entity: HAD
stoichiometric coefficient: 1.0

LEFT 0 conversion R12 AHMDHP STOICHIOMETRY
type: Stoichiometry
physical entity: AHMDHP
stoichiometric coefficient: 1.0

RIGHT 0 conversion R21 dTMP STOICHIOMETRY
type: Stoichiometry
physical entity: dTMP
stoichiometric coefficient: 1.0

ffTHFGlu
type: SmallMolecule
xref: C03479

C00493
type: UnificationXref
id: C00493
db: KEGG Compound

C00251
type: UnificationXref
id: C00251
db: KEGG Compound

C02430
type: UnificationXref
id: C02430
db: KEGG Compound

Hcy
type: PhysicalEntity
member physical entity: Hcy
cellular location: Single celled micro-organism

BioModels Database
type: Provenance
xref: BIOMD0000000725

PEP
type: PhysicalEntity
member physical entity: PEP
cellular location: Single celled micro-organism

pABA
type: SmallMolecule
xref: C00568

C00234
type: UnificationXref
id: C00234
db: KEGG Compound

Lp
type: PhysicalEntity
member physical entity: Lp
cellular location: Single celled micro-organism

dTMP
type: PhysicalEntity
member physical entity: dTMP
cellular location: Single celled micro-organism

BioModels Database
type: Provenance
xref: MODEL1511020000

ffTHFGlu
type: PhysicalEntity
member physical entity: ffTHFGlu
cellular location: Single celled micro-organism

dUMP
type: SmallMolecule
xref: C00365

DHSK
type: SmallMolecule
xref: C02637

Pi
type: PhysicalEntity
member physical entity: Pi
cellular location: Single celled micro-organism

NADP
type: PhysicalEntity
member physical entity: NADP
cellular location: Single celled micro-organism

C00364
type: UnificationXref
id: C00364
db: KEGG Compound

AHMDPP
type: PhysicalEntity
member physical entity: AHMDPP
cellular location: Single celled micro-organism

ATP
type: PhysicalEntity
member physical entity: ATP
cellular location: Single celled micro-organism

Gly
type: PhysicalEntity
member physical entity: Gly
cellular location: Single celled micro-organism

SAmDLp
type: PhysicalEntity
member physical entity: SAmDLp
cellular location: Single celled micro-organism

LEFT 1 conversion R12 ATP STOICHIOMETRY
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

R03460
type: UnificationXref
id: R03460
db: KEGG Reaction

Glu
type: PhysicalEntity
member physical entity: Glu
cellular location: Single celled micro-organism

Pi
type: SmallMolecule
xref: C00009

meTHFGlu
type: PhysicalEntity
member physical entity: meTHFGlu
cellular location: Single celled micro-organism

C00415
type: UnificationXref
id: C00415
db: KEGG Compound

PTHP
type: SmallMolecule
xref: C03684

LEFT 0 conversion R23 meTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: meTHFGlu
stoichiometric coefficient: 1.0

RIGHT 0 conversion R20 THFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: THFGlu
stoichiometric coefficient: 1.0

MODEL1511020000
type: UnificationXref
id: MODEL1511020000
db: BioModels Database

R18a - Dihydrolipoamide dehydrogenase
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R18a Lp STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R18a NAD STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R18a NADH STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R18a DLp STOICHIOMETRY
xref: R03815
right: NAD
right: DLp
left: Lp
left: NADH

R18c - S-Aminomethyldihydrolipoylprotein:tetrahydrofolate aminomethyltransferase (T protein)
type: BiochemicalReaction
participant stoichiometry: RIGHT 1 conversion R18c Lp STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion R18c THFGlu STOICHIOMETRY
participant stoichiometry: RIGHT 2 conversion R18c Ammonia STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R18c SAmDLp STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R18c myTHFGlu STOICHIOMETRY
xref: R04125
right: Ammonia
right: myTHFGlu
right: Lp
left: THFGlu
left: SAmDLp

R18b - Glycine decarboxylase (P protein)
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion R18b DLp STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion R18b SAmDLp STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion R18b Gly STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion R18b COTwo STOICHIOMETRY
xref: R03425
right: SAmDLp
right: COTwo
left: DLp
left: Gly

RIGHT 0 conversion R24 THFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: THFGlu
stoichiometric coefficient: 1.0

dTMP
type: SmallMolecule
xref: C00364

C00445
type: UnificationXref
id: C00445
db: KEGG Compound

RIGHT 1 conversion R13 Pi STOICHIOMETRY
type: Stoichiometry
physical entity: Pi
stoichiometric coefficient: 1.0

LEFT 0 conversion R21 myTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: myTHFGlu
stoichiometric coefficient: 1.0

C00568
type: UnificationXref
id: C00568
db: KEGG Compound

RIGHT 0 conversion R23 fTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: fTHFGlu
stoichiometric coefficient: 1.0

RIGHT 2 conversion R18c Ammonia STOICHIOMETRY
type: Stoichiometry
physical entity: Ammonia
stoichiometric coefficient: 1.0

LEFT 1 conversion R13 pABA STOICHIOMETRY
type: Stoichiometry
physical entity: pABA
stoichiometric coefficient: 1.0

C04807
type: UnificationXref
id: C04807
db: KEGG Compound

R02237
type: UnificationXref
id: R02237
db: KEGG Reaction

LEFT 0 conversion R8 CM STOICHIOMETRY
type: Stoichiometry
physical entity: CM
stoichiometric coefficient: 1.0

CVPSK
type: PhysicalEntity
member physical entity: CVPSK
cellular location: Single celled micro-organism

SK
type: SmallMolecule
xref: C00493

DAHP
type: SmallMolecule
xref: C04691

DHP
type: PhysicalEntity
member physical entity: DHP
cellular location: Single celled micro-organism

C02972
type: UnificationXref
id: C02972
db: KEGG Compound

myTHFGlu
type: PhysicalEntity
member physical entity: myTHFGlu
cellular location: Single celled micro-organism

LEFT 1 conversion R4 NADPH STOICHIOMETRY
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

HAD
type: SmallMolecule
xref: C00266

AMP
type: PhysicalEntity
member physical entity: AMP
cellular location: Single celled micro-organism

LEFT 1 conversion R18a NADH STOICHIOMETRY
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

RIGHT 1 conversion R25 THFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: THFGlu
stoichiometric coefficient: 1.0

RIGHT 0 conversion R26 THFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: THFGlu
stoichiometric coefficient: 1.0

LEFT 0 conversion R6 SKP STOICHIOMETRY
type: Stoichiometry
physical entity: SKP
stoichiometric coefficient: 1.0

C00440
type: UnificationXref
id: C00440
db: KEGG Compound

ATP
type: SmallMolecule
xref: C00002

NAD
type: PhysicalEntity
member physical entity: NAD
cellular location: Single celled micro-organism

AHMDHP
type: SmallMolecule
xref: C01300

RIGHT 1 conversion R9 Pyr STOICHIOMETRY
type: Stoichiometry
physical entity: Pyr
stoichiometric coefficient: 1.0

LEFT 0 conversion R17 THFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: THFGlu
stoichiometric coefficient: 1.0

CVPSK
type: SmallMolecule
xref: C01269

ADP
type: PhysicalEntity
member physical entity: ADP
cellular location: Single celled micro-organism

RIGHT 1 conversion R18c Lp STOICHIOMETRY
type: Stoichiometry
physical entity: Lp
stoichiometric coefficient: 1.0

PEP
type: PhysicalEntity
member physical entity: PEP
cellular location: Single celled micro-organism

ATP
type: PhysicalEntity
member physical entity: ATP
cellular location: Single celled micro-organism

fTHFGlu
type: PhysicalEntity
member physical entity: fTHFGlu
cellular location: Single celled micro-organism

LEFT 0 conversion R26 fTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: fTHFGlu
stoichiometric coefficient: 1.0

MAMO_0000046
type: UnificationXref
id: MAMO_0000046
db: Mathematical Modelling Ontology

R04125
type: UnificationXref
id: R04125
db: KEGG Reaction

RIGHT 0 conversion R6 CVPSK STOICHIOMETRY
type: Stoichiometry
physical entity: CVPSK
stoichiometric coefficient: 1.0

RIGHT 1 conversion R4 NADP STOICHIOMETRY
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

NADPH
type: PhysicalEntity
member physical entity: NADPH
cellular location: Single celled micro-organism

LEFT 1 conversion R6 PEP STOICHIOMETRY
type: Stoichiometry
physical entity: PEP
stoichiometric coefficient: 1.0

R04241
type: UnificationXref
id: R04241
db: KEGG Reaction

THF
type: PhysicalEntity
member physical entity: THF
cellular location: Single celled micro-organism

LEFT 0 conversion R7 CVPSK STOICHIOMETRY
type: Stoichiometry
physical entity: CVPSK
stoichiometric coefficient: 1.0

RIGHT 0 conversion R19 MTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: MTHFGlu
stoichiometric coefficient: 1.0

RIGHT 2 conversion R14 Pi STOICHIOMETRY
type: Stoichiometry
physical entity: Pi
stoichiometric coefficient: 1.0

THFGlu
type: PhysicalEntity
member physical entity: THFGlu
cellular location: Single celled micro-organism

Hcy
type: SmallMolecule
xref: C00155

NADPH
type: SmallMolecule
xref: C00005

PW:0001369
type: UnificationXref
id: PW:0001369
db: Pathway Ontology

SAmDLp
type: PhysicalEntity
member physical entity: SAmDLp
cellular location: Single celled micro-organism

LEFT 0 conversion R5 SK STOICHIOMETRY
type: Stoichiometry
physical entity: SK
stoichiometric coefficient: 1.0

LEFT 1 conversion R8 Gln STOICHIOMETRY
type: Stoichiometry
physical entity: Gln
stoichiometric coefficient: 1.0

RIGHT 0 conversion R27 PTHP STOICHIOMETRY
type: Stoichiometry
physical entity: PTHP
stoichiometric coefficient: 1.0

LEFT 1 conversion R20 Hcy STOICHIOMETRY
type: Stoichiometry
physical entity: Hcy
stoichiometric coefficient: 1.0

DHF
type: PhysicalEntity
member physical entity: DHF
cellular location: Single celled micro-organism

ADC
type: PhysicalEntity
member physical entity: ADC
cellular location: Single celled micro-organism

RIGHT 0 conversion R18b SAmDLp STOICHIOMETRY
type: Stoichiometry
physical entity: SAmDLp
stoichiometric coefficient: 1.0

dUMP
type: PhysicalEntity
member physical entity: dUMP
cellular location: Single celled micro-organism

http://identifiers.org/efo/0005741
type: UnificationXref
id: 0005741
db: Experimental Factor Ontology

COTwo
type: PhysicalEntity
member physical entity: COTwo
cellular location: Single celled micro-organism

LEFT 1 conversion R5 ATP STOICHIOMETRY
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

RIGHT 0 conversion R10 DHNTP STOICHIOMETRY
type: Stoichiometry
physical entity: DHNTP
stoichiometric coefficient: 1.0

LEFT 0 conversion R10 GTP STOICHIOMETRY
type: Stoichiometry
physical entity: GTP
stoichiometric coefficient: 1.0

Ammonia
type: SmallMolecule
xref: C00014

R05553
type: UnificationXref
id: R05553
db: KEGG Reaction

LEFT 0 conversion R3 DHQ STOICHIOMETRY
type: Stoichiometry
physical entity: DHQ
stoichiometric coefficient: 1.0

LEFT 0 conversion R27 DHNTP STOICHIOMETRY
type: Stoichiometry
physical entity: DHNTP
stoichiometric coefficient: 1.0

Glu
type: PhysicalEntity
member physical entity: Glu
cellular location: Single celled micro-organism

DLp
type: PhysicalEntity
member physical entity: DLp
cellular location: Single celled micro-organism

LEFT 1 conversion R25 mtRNA STOICHIOMETRY
type: Stoichiometry
physical entity: mtRNA
stoichiometric coefficient: 1.0

pABA
type: PhysicalEntity
member physical entity: pABA
cellular location: Single celled micro-organism

C00944
type: UnificationXref
id: C00944
db: KEGG Compound

ATP
type: PhysicalEntity
member physical entity: ATP
cellular location: Single celled micro-organism

RIGHT 1 conversion R18a NAD STOICHIOMETRY
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ADP
type: PhysicalEntity
member physical entity: ADP
cellular location: Single celled micro-organism

R03067
type: UnificationXref
id: R03067
db: KEGG Reaction

Formyl
type: PhysicalEntity
member physical entity: Formyl
cellular location: Single celled micro-organism

DLp
type: PhysicalEntity
member physical entity: DLp
cellular location: Single celled micro-organism

RIGHT 0 conversion R29 ADP STOICHIOMETRY
type: Stoichiometry
physical entity: ADP
stoichiometric coefficient: 1.0

MTHFGlu
type: PhysicalEntity
member physical entity: MTHFGlu
cellular location: Single celled micro-organism

RIGHT 1 conversion R29 Pi STOICHIOMETRY
type: Stoichiometry
physical entity: Pi
stoichiometric coefficient: 1.0

SK
type: PhysicalEntity
member physical entity: SK
cellular location: Single celled micro-organism

RIGHT 1 conversion R16 ADP STOICHIOMETRY
type: Stoichiometry
physical entity: ADP
stoichiometric coefficient: 1.0

RIGHT 1 conversion R1 Pi STOICHIOMETRY
type: Stoichiometry
physical entity: Pi
stoichiometric coefficient: 1.0

NADPH
type: PhysicalEntity
member physical entity: NADPH
cellular location: Single celled micro-organism

THFGlu
type: PhysicalEntity
member physical entity: THFGlu
cellular location: Single celled micro-organism

LEFT 0 conversion R22 myTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: myTHFGlu
stoichiometric coefficient: 1.0

meTHFGlu
type: SmallMolecule
xref: C00445

Formyl
type: SmallMolecule
xref: C00058

RIGHT 0 conversion R14 DHF STOICHIOMETRY
type: Stoichiometry
physical entity: DHF
stoichiometric coefficient: 1.0

R04286
type: UnificationXref
id: R04286
db: KEGG Reaction

RIGHT 0 conversion R1 DAHP STOICHIOMETRY
type: Stoichiometry
physical entity: DAHP
stoichiometric coefficient: 1.0

ATP
type: PhysicalEntity
member physical entity: ATP
cellular location: Single celled micro-organism

LEFT 0 conversion R9 ADC STOICHIOMETRY
type: Stoichiometry
physical entity: ADC
stoichiometric coefficient: 1.0

RIGHT 0 conversion R3 DHSK STOICHIOMETRY
type: Stoichiometry
physical entity: DHSK
stoichiometric coefficient: 1.0

meTHFGlu
type: PhysicalEntity
member physical entity: meTHFGlu
cellular location: Single celled micro-organism

NADPH
type: PhysicalEntity
member physical entity: NADPH
cellular location: Single celled micro-organism

RIGHT 0 conversion R9 pABA STOICHIOMETRY
type: Stoichiometry
physical entity: pABA
stoichiometric coefficient: 1.0

LEFT 1 conversion R17 Ser STOICHIOMETRY
type: Stoichiometry
physical entity: Ser
stoichiometric coefficient: 1.0

Pyr
type: SmallMolecule
xref: C00022

DHQ
type: PhysicalEntity
member physical entity: DHQ
cellular location: Single celled micro-organism

SK
type: PhysicalEntity
member physical entity: SK
cellular location: Single celled micro-organism

LEFT 1 conversion R29 ffTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: ffTHFGlu
stoichiometric coefficient: 1.0

C14329
type: UnificationXref
id: C14329
db: NCIt

AHMDHP
type: PhysicalEntity
member physical entity: AHMDHP
cellular location: Single celled micro-organism

LEFT 0 conversion R20 MTHFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: MTHFGlu
stoichiometric coefficient: 1.0

EP
type: PhysicalEntity
member physical entity: EP
cellular location: Single celled micro-organism

RIGHT 0 conversion R8 ADC STOICHIOMETRY
type: Stoichiometry
physical entity: ADC
stoichiometric coefficient: 1.0

RIGHT 2 conversion R24 Formyl STOICHIOMETRY
type: Stoichiometry
physical entity: Formyl
stoichiometric coefficient: 1.0

Pi
type: PhysicalEntity
member physical entity: Pi
cellular location: Single celled micro-organism

NADP
type: PhysicalEntity
member physical entity: NADP
cellular location: Single celled micro-organism

DAHP
type: PhysicalEntity
member physical entity: DAHP
cellular location: Single celled micro-organism

COTwo
type: PhysicalEntity
member physical entity: COTwo
cellular location: Single celled micro-organism

DHNTP
type: PhysicalEntity
member physical entity: DHNTP
cellular location: Single celled micro-organism

Pi
type: PhysicalEntity
member physical entity: Pi
cellular location: Single celled micro-organism

RIGHT 0 conversion R12 AHMDPP STOICHIOMETRY
type: Stoichiometry
physical entity: AHMDPP
stoichiometric coefficient: 1.0

DHNTP
type: SmallMolecule
xref: C04895

DHF
type: PhysicalEntity
member physical entity: DHF
cellular location: Single celled micro-organism

LEFT 0 conversion R15 DHF STOICHIOMETRY
type: Stoichiometry
physical entity: DHF
stoichiometric coefficient: 1.0

C03294
type: UnificationXref
id: C03294
db: KEGG Compound

C03175
type: UnificationXref
id: C03175
db: KEGG Compound

RIGHT 0 conversion R7 CM STOICHIOMETRY
type: Stoichiometry
physical entity: CM
stoichiometric coefficient: 1.0

Salcedo Sora2016 Microbial folate biosynthesis and utilisation
type: Pathway
pathway component: R11 - Dihydroneopterin aldolase
pathway component: R10 - GTP 7,8,9-dihydrolase (GTP cyclohydrolase I)
pathway component: R13 - Dihydropteroate synthase
pathway component: R12 - 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
pathway component: R15 - Dihydrofolate reductase
pathway component: R14 - 7,8-Dihydrofolate synthase
pathway component: R17 - Serine hydroxymethyltransferase
pathway component: R16 - Folylpoly-gamma-glutamate synthase
pathway component: R19 - 5,10-Methylenetetrahydrofolate reductase
pathway component: R20 - Methionine synthase
pathway component: R1 - Synthesis of 3-Deoxy-7-phosphoheptulonate
pathway component: R22 - 5,10-Methylenetetrahydrofolate dehydrogenase
pathway component: R2 - 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate phosphate-lyase (3-Dehydroquinate synthase)
pathway component: R21 - Thymidylate synthase
pathway component: R3 - 3-Dehydroquinate hydro-lyase (3-Dehydroquinate dehydratase)
pathway component: R24 - 10-Formyltetrahydrofolate synthetase
pathway component: R4 - Shikimate:NADP + 3-oxidoreductase (Shikimate 5-dehydrogenase)
pathway component: R23 - 5,10-Methenyltetrahydrofolate cyclohydrolase
pathway component: R5 - ATP:Shikimate 3-phosphotransferase (Shikimate kinase)
pathway component: R26 - 10-Formyltetrahydrofolate dehydrogenase
pathway component: R6 - Phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase
pathway component: R25 - Methionyl-tRNA formyltransferase
pathway component: R7 - 5-O-(1-Carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate synthase)
pathway component: R28 - S-Aminomethyldihydrolipoylprotein:tetrahydrofolate aminomethyltransferase (T protein)
pathway component: R8 - Aminodeoxychorismate synthase
pathway component: R27 - 6-Pyruvoyltetrahydropterin synthase
pathway component: R9 - Aminodeoxychorismate lyase
pathway component: R29 - 5-formyltetrahydrofolate cyclo-ligase
pathway component: R18a - Dihydrolipoamide dehydrogenase
pathway component: R18c - S-Aminomethyldihydrolipoylprotein:tetrahydrofolate aminomethyltransferase (T protein)
pathway component: R18b - Glycine decarboxylase (P protein)
xref: http://identifiers.org/efo/0005741
xref: MODEL1511020000
xref: PW:0001369
xref: C38809
xref: C14329
xref: BIOMD0000000725
xref: MAMO_0000046
xref: C5MB00801H
comment: The original model, 'Salcedo_Sora2016___Microbial_folate_biosynthesis_and_utilisation', was published in BioModels Database (http://www.ebi.ac.uk/biomodels/).
comment: This BioPAX Level3 file was automatically generated on Apr 8, 2022 by SBML2BioPAX-3.1, BioModels.net, EMBL-EBI.
data source: BioModels Database

C00921
type: UnificationXref
id: C00921
db: KEGG Compound

LEFT 1 conversion R26 NADP STOICHIOMETRY
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

LEFT 1 conversion R22 NADP STOICHIOMETRY
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

THFGlu
type: PhysicalEntity
member physical entity: THFGlu
cellular location: Single celled micro-organism

THFGlu
type: PhysicalEntity
member physical entity: THFGlu
cellular location: Single celled micro-organism

LEFT 1 conversion R18b Gly STOICHIOMETRY
type: Stoichiometry
physical entity: Gly
stoichiometric coefficient: 1.0

LEFT 2 conversion R16 ATP STOICHIOMETRY
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

R03084
type: UnificationXref
id: R03084
db: KEGG Reaction

R03083
type: UnificationXref
id: R03083
db: KEGG Reaction

DHSK
type: PhysicalEntity
member physical entity: DHSK
cellular location: Single celled micro-organism

BIOMD0000000725
type: UnificationXref
id: BIOMD0000000725
db: BioModels Database

SKP
type: PhysicalEntity
member physical entity: SKP
cellular location: Single celled micro-organism

ATP
type: PhysicalEntity
member physical entity: ATP
cellular location: Single celled micro-organism

R00943
type: UnificationXref
id: R00943
db: KEGG Reaction

R00945
type: UnificationXref
id: R00945
db: KEGG Reaction

RIGHT 0 conversion R16 THFGlu STOICHIOMETRY
type: Stoichiometry
physical entity: THFGlu
stoichiometric coefficient: 1.0

R00946
type: UnificationXref
id: R00946
db: KEGG Reaction

GTP
type: PhysicalEntity
member physical entity: GTP
cellular location: Single celled micro-organism

R00941
type: UnificationXref
id: R00941
db: KEGG Reaction

PTHP
type: PhysicalEntity
member physical entity: PTHP
cellular location: Single celled micro-organism

Pi
type: PhysicalEntity
member physical entity: Pi
cellular location: Single celled micro-organism

CM
type: PhysicalEntity
member physical entity: CM
cellular location: Single celled micro-organism

R00939
type: UnificationXref
id: R00939
db: KEGG Reaction

RIGHT 1 conversion R7 Pi STOICHIOMETRY
type: Stoichiometry
physical entity: Pi
stoichiometric coefficient: 1.0