RIGHT 1 conversion Fe2Tf Rest Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

RIGHT 0 conversion NTBI Fe1Tf Fe1Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe1Tf
stoichiometric coefficient: 1.0

LEFT 0 conversion BM RBC 0 FeBM 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeBM_0
stoichiometric coefficient: 1.0

Duo_NTBI*
type: Transport
participant stoichiometry: RIGHT 0 conversion Duo NTBI NTBI STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Duo NTBI FeDuo STOICHIOMETRY
xref: GO:0006826
right: NTBI
left: FeDuo

Fe1Tf_0
type: PhysicalEntity
member physical entity: Fe1Tf
cellular location: Plasma

LEFT 0 conversion Fe2Tf Duo 0 Fe2Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf
stoichiometric coefficient: 1.0

FeRest
type: PhysicalEntity
member physical entity: FeRest*
cellular location: RestOfBody

Rest_NTBI*
type: Transport
participant stoichiometry: LEFT 0 conversion Rest NTBI FeRest STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Rest NTBI NTBI STOICHIOMETRY
xref: GO:0006826
right: NTBI
left: FeRest

RBC
type: CellularLocationVocabulary
xref: BTO:0000424

FeDuo
type: PhysicalEntity
member physical entity: FeDuo*
cellular location: Duodenum

LEFT 0 conversion Fe1Tf BM Fe1Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe1Tf
stoichiometric coefficient: 1.0

FeDuo_0
type: PhysicalEntity
member physical entity: FeDuo
cellular location: Duodenum

NTBI
type: PhysicalEntity
member physical entity: NTBI*
cellular location: Plasma

RIGHT 0 conversion RestLoss FeOutside STOICHIOMETRY
type: Stoichiometry
physical entity: FeOutside
stoichiometric coefficient: 1.0

Fe1Tf
type: PhysicalEntity
member physical entity: Fe1Tf*
cellular location: Plasma

Fe2Tf
type: PhysicalEntity
member physical entity: Fe2Tf*
cellular location: Plasma

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

RBC_Spleen
type: Transport
participant stoichiometry: RIGHT 0 conversion RBC Spleen 0 FeSpleen 0 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion RBC Spleen 0 FeRBC 0 STOICHIOMETRY
xref: GO:0006826
right: FeSpleen_0
left: FeRBC_0

C15222
type: UnificationXref
id: C15222
db: NCIt

RIGHT 0 conversion Fe2Tf Rest FeRest STOICHIOMETRY
type: Stoichiometry
physical entity: FeRest
stoichiometric coefficient: 2.0

RIGHT 0 conversion Fe2Tf Liver 0 FeLiver STOICHIOMETRY
type: Stoichiometry
physical entity: FeLiver
stoichiometric coefficient: 1.0

FeOutside*
type: SmallMolecule
xref: CHEBI:24875

LEFT 0 conversion NTBI Fe1Tf NTBI STOICHIOMETRY
type: Stoichiometry
physical entity: NTBI
stoichiometric coefficient: 1.0

Spleen
type: CellularLocationVocabulary
xref: BTO:0001281

FeSpleen_0
type: PhysicalEntity
member physical entity: FeSpleen
cellular location: Spleen

DuoLoss
type: Transport
participant stoichiometry: LEFT 0 conversion DuoLoss 0 FeDuo 0 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion DuoLoss 0 FeOutside 0 STOICHIOMETRY
xref: C25559
right: FeOutside_0
left: FeDuo_0

LEFT 0 conversion Fe1Tf BM 0 Fe1Tf 0 STOICHIOMETRY
type: Stoichiometry
physical entity: Fe1Tf_0
stoichiometric coefficient: 1.0

LEFT 0 conversion Fe1Tf Fe2Tf 0 Fe1Tf 0 STOICHIOMETRY
type: Stoichiometry
physical entity: Fe1Tf_0
stoichiometric coefficient: 1.0

LEFT 0 conversion DuoLoss FeDuo STOICHIOMETRY
type: Stoichiometry
physical entity: FeDuo
stoichiometric coefficient: 1.0

FeRBC_0
type: PhysicalEntity
member physical entity: FeRBC
cellular location: RBC

FeRest_0
type: PhysicalEntity
member physical entity: FeRest
cellular location: RestOfBody

RIGHT 0 conversion Spleen NTBI 0 NTBI 0 STOICHIOMETRY
type: Stoichiometry
physical entity: NTBI_0
stoichiometric coefficient: 1.0

LEFT 0 conversion Fe2Tf BM Fe2Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf_
stoichiometric coefficient: 1.0

Fe1Tf_Duo
type: Transport
participant stoichiometry: RIGHT 1 conversion Fe1Tf Duo 0 Tf STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe1Tf Duo 0 Fe1Tf 0 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe1Tf Duo 0 FeDuo 0 STOICHIOMETRY
xref: GO:0006826
right: Tf
right: FeDuo_0
left: Fe1Tf_0

FeBM
type: PhysicalEntity
member physical entity: FeBM
cellular location: BoneMarrow

RIGHT 1 conversion Fe2Tf BM 0 FeBM STOICHIOMETRY
type: Stoichiometry
physical entity: FeBM
stoichiometric coefficient: 1.0

FeOutside
type: PhysicalEntity
member physical entity: FeOutside*
cellular location: RestOfBody

FeDuo
type: PhysicalEntity
member physical entity: FeDuo*
cellular location: Duodenum

RIGHT 0 conversion Fe1Tf Rest 0 FeRest 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeRest_0
stoichiometric coefficient: 1.0

RIGHT 0 conversion Fe1Tf Duo 0 FeDuo 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeDuo_0
stoichiometric coefficient: 1.0

CHEBI:29034
type: UnificationXref
id: CHEBI:29034
db: ChEBI

RIGHT 1 conversion Fe2Tf Rest 0 FeRest 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeRest_0
stoichiometric coefficient: 1.0

NTBI
type: PhysicalEntity
member physical entity: NTBI*
cellular location: Plasma

Duo_NTBI
type: Transport
participant stoichiometry: RIGHT 0 conversion Duo NTBI 0 NTBI 0 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Duo NTBI 0 FeDuo 0 STOICHIOMETRY
xref: GO:0006826
right: NTBI_0
left: FeDuo_0

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

LEFT 0 conversion Fe2Tf BM Fe2Tf 0 STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf_0
stoichiometric coefficient: 1.0

BTO:0000365
type: UnificationXref
id: BTO:0000365
db: Brenda Tissue Ontology

RIGHT 0 conversion BM Spleen 0 FeSpleen STOICHIOMETRY
type: Stoichiometry
physical entity: FeSpleen
stoichiometric coefficient: 1.0

Fe1Tf_BM
type: Transport
participant stoichiometry: RIGHT 1 conversion Fe1Tf BM 0 Tf STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe1Tf BM 0 Fe1Tf 0 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe1Tf BM 0 FeBM STOICHIOMETRY
xref: GO:0006826
right: FeBM
right: Tf
left: Fe1Tf_0

BTO:0000131
type: UnificationXref
id: BTO:0000131
db: Brenda Tissue Ontology

Fe2Tf_Duo**
type: Transport
participant stoichiometry: RIGHT 1 conversion Fe2Tf Duo Tf STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe2Tf Duo FeDuo STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe2Tf Duo Fe2Tf STOICHIOMETRY
xref: GO:0006826
right: FeDuo
right: Tf
left: Fe2Tf_

RIGHT 0 conversion Fe2Tf Duo FeDuo STOICHIOMETRY
type: Stoichiometry
physical entity: FeDuo
stoichiometric coefficient: 2.0

NTBI
type: PhysicalEntity
member physical entity: NTBI*
cellular location: Plasma

FeRest
type: SmallMolecule
xref: CHEBI:24875

LEFT 0 conversion Fe2Tf Duo Fe2Tf 0 STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf_0
stoichiometric coefficient: 1.0

FeDuo_0
type: PhysicalEntity
member physical entity: FeDuo
cellular location: Duodenum

RIGHT 2 conversion Fe2Tf Duo 0 Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

RIGHT 0 conversion RBC Spleen 0 FeSpleen 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeSpleen_0
stoichiometric coefficient: 1.0

LEFT 1 conversion NTBI Fe1Tf Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

Duodenum
type: CellularLocationVocabulary
xref: BTO:0000365

RIGHT 1 conversion Fe2Tf Duo Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

Fe2Tf_0
type: PhysicalEntity
member physical entity: Fe2Tf
cellular location: Plasma

BM_RBC
type: Transport
participant stoichiometry: LEFT 0 conversion BM RBC FeBM STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion BM RBC FeRBC 0 STOICHIOMETRY
xref: GO:0006826
right: FeRBC_0
left: FeBM

RIGHT 0 conversion Fe1Tf Liver FeLiver STOICHIOMETRY
type: Stoichiometry
physical entity: FeLiver
stoichiometric coefficient: 1.0

Fe1Tf_0
type: PhysicalEntity
member physical entity: Fe1Tf
cellular location: Plasma

FeBM
type: PhysicalEntity
member physical entity: FeBM
cellular location: BoneMarrow

BTO:0000141
type: UnificationXref
id: BTO:0000141
db: Brenda Tissue Ontology

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

LEFT 0 conversion BM RBC FeBM STOICHIOMETRY
type: Stoichiometry
physical entity: FeBM
stoichiometric coefficient: 1.0

FeSpleen
type: PhysicalEntity
member physical entity: FeSpleen*
cellular location: Spleen

Fe1Tf_BM*
type: Transport
participant stoichiometry: LEFT 0 conversion Fe1Tf BM Fe1Tf STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe1Tf BM FeBM 0 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion Fe1Tf BM Tf STOICHIOMETRY
xref: GO:0006826
right: Tf
right: FeBM_0
left: Fe1Tf

FeRBC
type: SmallMolecule
xref: CHEBI:24875

FeSpleen
type: SmallMolecule
xref: CHEBI:24875

FeRest*
type: SmallMolecule
xref: CHEBI:24875

NTBI
type: PhysicalEntity
member physical entity: NTBI*
cellular location: Plasma

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

RIGHT 1 conversion Fe1Tf BM Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

FeDuo_0
type: PhysicalEntity
member physical entity: FeDuo
cellular location: Duodenum

Fe2Tf
type: PhysicalEntity
member physical entity: Fe2Tf*
cellular location: Plasma

Q9EQ21
type: UnificationXref
id: Q9EQ21
db: UniProt Knowledgebase

RBC_Spleen*
type: Transport
participant stoichiometry: LEFT 0 conversion RBC Spleen FeRBC STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion RBC Spleen FeSpleen STOICHIOMETRY
xref: GO:0006826
right: FeSpleen
left: FeRBC

Fe1Tf_Rest
type: Transport
participant stoichiometry: RIGHT 1 conversion Fe1Tf Rest 0 Tf STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe1Tf Rest 0 FeRest 0 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe1Tf Rest 0 Fe1Tf 0 STOICHIOMETRY
xref: GO:0006826
right: Tf
right: FeRest_0
left: Fe1Tf_0

Diet
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion Diet FeDuo 0 STOICHIOMETRY
xref: C15222
right: FeDuo_0

Liver
type: CellularLocationVocabulary
xref: BTO:0000759

RIGHT 0 conversion Fe2Tf Duo 0 FeDuo STOICHIOMETRY
type: Stoichiometry
physical entity: FeDuo
stoichiometric coefficient: 1.0

BTO:0000424
type: UnificationXref
id: BTO:0000424
db: Brenda Tissue Ontology

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

RIGHT 0 conversion Fe1Tf Fe2Tf Fe2Tf 0 STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf_0
stoichiometric coefficient: 1.0

BM_RBC*
type: Transport
participant stoichiometry: RIGHT 0 conversion BM RBC 0 FeRBC STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion BM RBC 0 FeBM 0 STOICHIOMETRY
xref: GO:0006826
right: FeRBC
left: FeBM_0

GO:0055072
type: UnificationXref
id: GO:0055072
db: Gene Ontology

Tf
type: Protein
xref: Q921I1

RIGHT 0 conversion Fe2Tf Duo FeDuo 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeDuo_0
stoichiometric coefficient: 2.0

RIGHT 1 conversion Fe2Tf Rest Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

FeDuo*
type: SmallMolecule
xref: CHEBI:24875

Fe2Tf_0
type: PhysicalEntity
member physical entity: Fe2Tf
cellular location: Plasma

CHEBI:24875
type: UnificationXref
id: CHEBI:24875
db: ChEBI

FeLiver_0
type: PhysicalEntity
member physical entity: FeLiver
cellular location: Liver

LEFT 0 conversion Rest NTBI 0 FeRest 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeRest_0
stoichiometric coefficient: 1.0

RIGHT 1 conversion Fe2Tf Duo Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

LEFT 1 conversion Fe1Tf Fe2Tf NTBI 0 STOICHIOMETRY
type: Stoichiometry
physical entity: NTBI_0
stoichiometric coefficient: 1.0

MAMO_0000046
type: UnificationXref
id: MAMO_0000046
db: Mathematical Modelling Ontology

LEFT 0 conversion RBC Spleen 0 FeRBC 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeRBC_0
stoichiometric coefficient: 1.0

http://identifiers.org/taxonomy/10090
type: UnificationXref
id: 10090
db: Taxonomy

FeDuo
type: PhysicalEntity
member physical entity: FeDuo*
cellular location: Duodenum

NTBI_0
type: PhysicalEntity
member physical entity: NTBI
cellular location: Plasma

RestOfBody
type: CellularLocationVocabulary

LEFT 0 conversion BM Spleen 0 FeBM 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeBM_0
stoichiometric coefficient: 1.0

NTBI*
type: SmallMolecule
xref: CHEBI:24875

Fe1Tf_Rest*
type: Transport
participant stoichiometry: RIGHT 1 conversion Fe1Tf Rest Tf STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe1Tf Rest FeRest STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe1Tf Rest Fe1Tf STOICHIOMETRY
xref: GO:0006826
right: Tf
right: FeRest
left: Fe1Tf

FeRest_0
type: PhysicalEntity
member physical entity: FeRest
cellular location: RestOfBody

FeLiver_0
type: PhysicalEntity
member physical entity: FeLiver
cellular location: Liver

Fe2Tf_BM*
type: Transport
participant stoichiometry: RIGHT 1 conversion Fe2Tf BM 0 FeBM STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe2Tf BM 0 Fe2Tf STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe2Tf BM 0 FeBM 0 STOICHIOMETRY
participant stoichiometry: RIGHT 2 conversion Fe2Tf BM 0 Tf STOICHIOMETRY
xref: GO:0006826
right: FeBM_0
right: FeBM
right: Tf
left: Fe2Tf

FeBM
type: PhysicalEntity
member physical entity: FeBM
cellular location: BoneMarrow

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

HepcidinDecay
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion HepcidinDecay Hepcidin STOICHIOMETRY
xref: C75947
left: Hepcidin

RIGHT 1 conversion Fe2Tf BM Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

Mouse Iron Distribution Adequate iron diet tracer
type: Pathway
pathway component: RBC_Spleen*
pathway component: Fe1Tf_Rest
pathway component: Diet
pathway component: Rest_NTBI
pathway component: RestLoss*
pathway component: BM_Spleen
pathway component: Fe1Tf*_Fe2Tf**
pathway component: Duo_NTBI
pathway component: Duo_NTBI*
pathway component: DuoLoss*
pathway component: BM_RBC*
pathway component: Fe2Tf_Rest**
pathway component: Fe1Tf_BM
pathway component: Rest_NTBI*
pathway component: Liver_NTBI
pathway component: Fe1Tf*_Fe2Tf*
pathway component: Fe2Tf_Duo**
pathway component: Fe1Tf_Liver
pathway component: Fe2Tf_BM**
pathway component: Spleen_NTBI*
pathway component: RBC_Spleen
pathway component: Fe2Tf_BM
pathway component: HepcidinSynthesis
pathway component: NTBI_Fe1Tf*
pathway component: Fe2Tf_Rest
pathway component: Fe1Tf_Duo*
pathway component: Fe2Tf_Duo*
pathway component: DuoLoss
pathway component: BM_RBC
pathway component: BM_Spleen*
pathway component: Fe1Tf_Liver*
pathway component: Fe1Tf_Rest*
pathway component: Fe1Tf_Duo
pathway component: Fe2Tf_BM*
pathway component: Fe2Tf_Liver**
pathway component: Fe1Tf_BM*
pathway component: Spleen_NTBI
pathway component: HepcidinDecay
pathway component: Fe2Tf_Liver
pathway component: Fe2Tf_Liver*
pathway component: Fe1Tf_Fe2Tf
pathway component: Fe1Tf_Fe2Tf*
pathway component: Fe2Tf_Rest*
pathway component: Liver_NTBI*
pathway component: NTBI_Fe1Tf
pathway component: RestLoss
pathway component: Fe2Tf_Duo
xref: MODEL1605030002
xref: BIOMD0000000735
xref: http://identifiers.org/pubmed/28521769
xref: GO:0055072
xref: MAMO_0000046
organism: biosource 1
comment: This BioPAX Level3 file was automatically generated on Apr 8, 2022 by SBML2BioPAX-3.1, BioModels.net, EMBL-EBI.
comment: The original model, 'Mouse_Iron_Distribution___Adequate_iron_diet__tracer', was published in BioModels Database (http://www.ebi.ac.uk/biomodels/).
data source: BioModels Database

RIGHT 0 conversion Duo NTBI NTBI STOICHIOMETRY
type: Stoichiometry
physical entity: NTBI
stoichiometric coefficient: 1.0

Fe1Tf_Fe2Tf*
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion Fe1Tf Fe2Tf 0 Fe1Tf 0 STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion Fe1Tf Fe2Tf 0 NTBI STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe1Tf Fe2Tf 0 Fe2Tf STOICHIOMETRY
xref: GO:0005488
right: Fe2Tf
left: NTBI
left: Fe1Tf_0

LEFT 0 conversion RestLoss 0 FeRest 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeRest_0
stoichiometric coefficient: 1.0

Fe2Tf
type: PhysicalEntity
member physical entity: Fe2Tf*
cellular location: Plasma

RestLoss
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion RestLoss 0 FeOutside 0 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion RestLoss 0 FeRest 0 STOICHIOMETRY
xref: C25559
right: FeOutside_0
left: FeRest_0

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

RIGHT 0 conversion HepcidinSynthesis Hepcidin STOICHIOMETRY
type: Stoichiometry
physical entity: Hepcidin
stoichiometric coefficient: 1.0

FeBM
type: PhysicalEntity
member physical entity: FeBM
cellular location: BoneMarrow

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

FeLiver*
type: SmallMolecule
xref: CHEBI:24875

FeOutside
type: PhysicalEntity
member physical entity: FeOutside*
cellular location: RestOfBody

LEFT 0 conversion Fe2Tf Rest Fe2Tf 0 STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf_0
stoichiometric coefficient: 1.0

Fe2Tf_
type: PhysicalEntity
member physical entity: Fe2Tf**
cellular location: Plasma

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

LEFT 0 conversion RBC Spleen FeRBC STOICHIOMETRY
type: Stoichiometry
physical entity: FeRBC
stoichiometric coefficient: 1.0

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

FeRest
type: PhysicalEntity
member physical entity: FeRest*
cellular location: RestOfBody

Fe2Tf_
type: PhysicalEntity
member physical entity: Fe2Tf**
cellular location: Plasma

Fe2Tf_BM
type: Transport
participant stoichiometry: RIGHT 0 conversion Fe2Tf BM FeBM STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe2Tf BM Fe2Tf 0 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion Fe2Tf BM Tf STOICHIOMETRY
xref: GO:0006826
right: FeBM
right: Tf
left: Fe2Tf_0

FeRBC*
type: SmallMolecule
xref: CHEBI:24875

Fe2Tf**
type: Complex
xref: Q921I1
xref: CHEBI:29034

RIGHT 1 conversion Fe1Tf Liver Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

RIGHT 1 conversion Fe1Tf BM 0 Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

RIGHT 1 conversion Fe1Tf Duo 0 Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

Fe1Tf_0
type: PhysicalEntity
member physical entity: Fe1Tf
cellular location: Plasma

BoneMarrow
type: CellularLocationVocabulary
xref: BTO:0000141

Fe2Tf_0
type: PhysicalEntity
member physical entity: Fe2Tf
cellular location: Plasma

LEFT 0 conversion BM Spleen FeBM STOICHIOMETRY
type: Stoichiometry
physical entity: FeBM
stoichiometric coefficient: 1.0

FeOutside
type: SmallMolecule
xref: CHEBI:24875

LEFT 0 conversion Fe1Tf Liver 0 Fe1Tf 0 STOICHIOMETRY
type: Stoichiometry
physical entity: Fe1Tf_0
stoichiometric coefficient: 1.0

Fe1Tf
type: PhysicalEntity
member physical entity: Fe1Tf*
cellular location: Plasma

LEFT 0 conversion Fe2Tf Liver Fe2Tf 0 STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf_0
stoichiometric coefficient: 1.0

FeLiver
type: PhysicalEntity
member physical entity: FeLiver*
cellular location: Liver

LEFT 1 conversion Fe1Tf Fe2Tf NTBI STOICHIOMETRY
type: Stoichiometry
physical entity: NTBI
stoichiometric coefficient: 1.0

Fe2Tf_0
type: PhysicalEntity
member physical entity: Fe2Tf
cellular location: Plasma

Fe2Tf
type: PhysicalEntity
member physical entity: Fe2Tf*
cellular location: Plasma

RIGHT 0 conversion Fe1Tf BM FeBM 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeBM_0
stoichiometric coefficient: 1.0

LEFT 0 conversion Fe2Tf BM 0 Fe2Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf
stoichiometric coefficient: 1.0

FeBM
type: PhysicalEntity
member physical entity: FeBM
cellular location: BoneMarrow

FeDuo
type: PhysicalEntity
member physical entity: FeDuo*
cellular location: Duodenum

RIGHT 1 conversion Fe2Tf Duo 0 FeDuo 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeDuo_0
stoichiometric coefficient: 1.0

FeLiver_0
type: PhysicalEntity
member physical entity: FeLiver
cellular location: Liver

LEFT 0 conversion Fe2Tf Duo Fe2Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf_
stoichiometric coefficient: 1.0

NTBI_Fe1Tf
type: ComplexAssembly
participant stoichiometry: LEFT 1 conversion NTBI Fe1Tf 0 Tf STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion NTBI Fe1Tf 0 Fe1Tf 0 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion NTBI Fe1Tf 0 NTBI 0 STOICHIOMETRY
xref: GO:0005488
right: Fe1Tf_0
spontaneous: true
left: Tf
left: NTBI_0
conversion direction: LEFT_TO_RIGHT

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

Fe1Tf
type: PhysicalEntity
member physical entity: Fe1Tf*
cellular location: Plasma

FeRest_0
type: PhysicalEntity
member physical entity: FeRest
cellular location: RestOfBody

RestLoss*
type: BiochemicalReaction
participant stoichiometry: LEFT 0 conversion RestLoss FeRest STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion RestLoss FeOutside STOICHIOMETRY
xref: C25559
right: FeOutside
left: FeRest

FeLiver
type: PhysicalEntity
member physical entity: FeLiver*
cellular location: Liver

RIGHT 0 conversion Fe2Tf BM FeBM STOICHIOMETRY
type: Stoichiometry
physical entity: FeBM
stoichiometric coefficient: 2.0

BM_Spleen
type: Transport
participant stoichiometry: RIGHT 0 conversion BM Spleen FeSpleen 0 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion BM Spleen FeBM STOICHIOMETRY
xref: GO:0006826
right: FeSpleen_0
left: FeBM

FeRBC_0
type: PhysicalEntity
member physical entity: FeRBC
cellular location: RBC

Fe2Tf*
type: Complex
xref: Q921I1
xref: CHEBI:29034

Fe2Tf_Rest**
type: Transport
participant stoichiometry: RIGHT 1 conversion Fe2Tf Rest Tf STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe2Tf Rest Fe2Tf STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe2Tf Rest FeRest STOICHIOMETRY
xref: GO:0006826
right: FeRest
right: Tf
left: Fe2Tf_

RIGHT 0 conversion Spleen NTBI NTBI STOICHIOMETRY
type: Stoichiometry
physical entity: NTBI
stoichiometric coefficient: 1.0

Fe1Tf_Liver
type: Transport
participant stoichiometry: RIGHT 0 conversion Fe1Tf Liver 0 FeLiver 0 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion Fe1Tf Liver 0 Tf STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe1Tf Liver 0 Fe1Tf 0 STOICHIOMETRY
xref: GO:0006826
right: FeLiver_0
right: Tf
left: Fe1Tf_0

BTO:0001281
type: UnificationXref
id: BTO:0001281
db: Brenda Tissue Ontology

Fe2Tf_BM**
type: Transport
participant stoichiometry: RIGHT 1 conversion Fe2Tf BM Tf STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe2Tf BM FeBM 0 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe2Tf BM Fe2Tf STOICHIOMETRY
xref: GO:0006826
right: Tf
right: FeBM_0
left: Fe2Tf_

Fe1Tf
type: PhysicalEntity
member physical entity: Fe1Tf*
cellular location: Plasma

LEFT 1 conversion NTBI Fe1Tf 0 Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

FeSpleen*
type: SmallMolecule
xref: CHEBI:24875

FeRest
type: PhysicalEntity
member physical entity: FeRest*
cellular location: RestOfBody

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

GO:0006826
type: UnificationXref
id: GO:0006826
db: Gene Ontology

NTBI_Fe1Tf*
type: ComplexAssembly
participant stoichiometry: LEFT 1 conversion NTBI Fe1Tf Tf STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion NTBI Fe1Tf Fe1Tf STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion NTBI Fe1Tf NTBI STOICHIOMETRY
xref: GO:0005488
right: Fe1Tf
spontaneous: true
left: NTBI
left: Tf
conversion direction: LEFT_TO_RIGHT

BTO:0000759
type: UnificationXref
id: BTO:0000759
db: Brenda Tissue Ontology

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

Fe1Tf_Duo*
type: Transport
participant stoichiometry: RIGHT 1 conversion Fe1Tf Duo Tf STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe1Tf Duo Fe1Tf STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe1Tf Duo FeDuo STOICHIOMETRY
xref: GO:0006826
right: Tf
right: FeDuo
left: Fe1Tf

FeLiver
type: PhysicalEntity
member physical entity: FeLiver*
cellular location: Liver

FeDuo_0
type: PhysicalEntity
member physical entity: FeDuo
cellular location: Duodenum

NTBI
type: SmallMolecule
xref: CHEBI:24875

RIGHT 0 conversion BM RBC FeRBC 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeRBC_0
stoichiometric coefficient: 1.0

Q921I1
type: UnificationXref
id: Q921I1
db: UniProt Knowledgebase

NTBI_0
type: PhysicalEntity
member physical entity: NTBI
cellular location: Plasma

LEFT 0 conversion Fe1Tf Fe2Tf Fe1Tf 0 STOICHIOMETRY
type: Stoichiometry
physical entity: Fe1Tf_0
stoichiometric coefficient: 1.0

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

RIGHT 0 conversion Duo NTBI 0 NTBI 0 STOICHIOMETRY
type: Stoichiometry
physical entity: NTBI_0
stoichiometric coefficient: 1.0

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

FeDuo_0
type: PhysicalEntity
member physical entity: FeDuo
cellular location: Duodenum

RIGHT 1 conversion Fe2Tf Liver Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

LEFT 0 conversion Fe1Tf Rest Fe1Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe1Tf
stoichiometric coefficient: 1.0

LEFT 0 conversion Fe1Tf Fe2Tf Fe1Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe1Tf
stoichiometric coefficient: 1.0

Fe1Tf_Fe2Tf
type: BiochemicalReaction
participant stoichiometry: LEFT 1 conversion Fe1Tf Fe2Tf NTBI 0 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe1Tf Fe2Tf Fe2Tf 0 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe1Tf Fe2Tf Fe1Tf 0 STOICHIOMETRY
xref: GO:0005488
right: Fe2Tf_0
left: Fe1Tf_0
left: NTBI_0

FeRest_0
type: PhysicalEntity
member physical entity: FeRest
cellular location: RestOfBody

FeBM_0
type: PhysicalEntity
member physical entity: FeBM*
cellular location: BoneMarrow

Fe2Tf
type: Complex
xref: Q921I1
xref: CHEBI:29034

NTBI_0
type: PhysicalEntity
member physical entity: NTBI
cellular location: Plasma

FeLiver_0
type: PhysicalEntity
member physical entity: FeLiver
cellular location: Liver

RIGHT 0 conversion Fe1Tf Rest FeRest STOICHIOMETRY
type: Stoichiometry
physical entity: FeRest
stoichiometric coefficient: 1.0

RIGHT 0 conversion BM Spleen FeSpleen 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeSpleen_0
stoichiometric coefficient: 1.0

Fe1Tf
type: PhysicalEntity
member physical entity: Fe1Tf*
cellular location: Plasma

RIGHT 0 conversion RestLoss 0 FeOutside 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeOutside_0
stoichiometric coefficient: 1.0

FeRBC
type: PhysicalEntity
member physical entity: FeRBC*
cellular location: RBC

Fe1Tf*_Fe2Tf**
type: BiochemicalReaction
participant stoichiometry: LEFT 1 conversion Fe1Tf Fe2Tf NTBI STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe1Tf Fe2Tf Fe1Tf STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe1Tf Fe2Tf Fe2Tf STOICHIOMETRY
xref: GO:0005488
right: Fe2Tf_
left: Fe1Tf
left: NTBI

RIGHT 0 conversion Fe1Tf BM 0 FeBM STOICHIOMETRY
type: Stoichiometry
physical entity: FeBM
stoichiometric coefficient: 1.0

Fe2Tf_
type: PhysicalEntity
member physical entity: Fe2Tf**
cellular location: Plasma

FeBM
type: SmallMolecule
xref: CHEBI:24875

RIGHT 0 conversion Diet FeDuo 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeDuo_0
stoichiometric coefficient: 1.0

Fe1Tf*
type: Complex
xref: Q921I1
xref: CHEBI:29034

C25559
type: UnificationXref
id: C25559
db: NCIt

LEFT 0 conversion Fe2Tf Liver 0 Fe2Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf
stoichiometric coefficient: 1.0

Spleen_NTBI*
type: Transport
participant stoichiometry: LEFT 0 conversion Spleen NTBI FeSpleen STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Spleen NTBI NTBI STOICHIOMETRY
xref: GO:0006826
right: NTBI
left: FeSpleen

RIGHT 1 conversion Fe1Tf Rest 0 Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

LEFT 0 conversion Fe1Tf Duo 0 Fe1Tf 0 STOICHIOMETRY
type: Stoichiometry
physical entity: Fe1Tf_0
stoichiometric coefficient: 1.0

Fe2Tf_Duo*
type: Transport
participant stoichiometry: RIGHT 0 conversion Fe2Tf Duo 0 FeDuo STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion Fe2Tf Duo 0 FeDuo 0 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe2Tf Duo 0 Fe2Tf STOICHIOMETRY
participant stoichiometry: RIGHT 2 conversion Fe2Tf Duo 0 Tf STOICHIOMETRY
xref: GO:0006826
right: FeDuo
right: FeDuo_0
right: Tf
left: Fe2Tf

NTBI_0
type: PhysicalEntity
member physical entity: NTBI
cellular location: Plasma

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

FeBM_0
type: PhysicalEntity
member physical entity: FeBM*
cellular location: BoneMarrow

Fe1Tf_Liver*
type: Transport
participant stoichiometry: RIGHT 1 conversion Fe1Tf Liver Tf STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe1Tf Liver Fe1Tf STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe1Tf Liver FeLiver STOICHIOMETRY
xref: GO:0006826
right: FeLiver
right: Tf
left: Fe1Tf

LEFT 0 conversion Fe1Tf Duo Fe1Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe1Tf
stoichiometric coefficient: 1.0

LEFT 0 conversion HepcidinDecay Hepcidin STOICHIOMETRY
type: Stoichiometry
physical entity: Hepcidin
stoichiometric coefficient: 1.0

Fe2Tf_Liver**
type: Transport
participant stoichiometry: LEFT 0 conversion Fe2Tf Liver Fe2Tf STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion Fe2Tf Liver Tf STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe2Tf Liver FeLiver STOICHIOMETRY
xref: GO:0006826
right: FeLiver
right: Tf
left: Fe2Tf_

Spleen_NTBI
type: Transport
participant stoichiometry: RIGHT 0 conversion Spleen NTBI 0 NTBI 0 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Spleen NTBI 0 FeSpleen 0 STOICHIOMETRY
xref: GO:0006826
right: NTBI_0
left: FeSpleen_0

RIGHT 0 conversion BM RBC 0 FeRBC STOICHIOMETRY
type: Stoichiometry
physical entity: FeRBC
stoichiometric coefficient: 1.0

MODEL1605030002
type: UnificationXref
id: MODEL1605030002
db: BioModels Database

LEFT 0 conversion Rest NTBI FeRest STOICHIOMETRY
type: Stoichiometry
physical entity: FeRest
stoichiometric coefficient: 1.0

FeOutside_0
type: PhysicalEntity
member physical entity: FeOutside
cellular location: RestOfBody

FeSpleen
type: PhysicalEntity
member physical entity: FeSpleen*
cellular location: Spleen

Rest_NTBI
type: Transport
participant stoichiometry: RIGHT 0 conversion Rest NTBI 0 NTBI 0 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Rest NTBI 0 FeRest 0 STOICHIOMETRY
xref: GO:0006826
right: NTBI_0
left: FeRest_0

RIGHT 0 conversion Fe1Tf Fe2Tf Fe2Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf
stoichiometric coefficient: 1.0

Hepcidin
type: PhysicalEntity
member physical entity: Hepcidin
cellular location: Plasma

Fe1Tf
type: PhysicalEntity
member physical entity: Fe1Tf*
cellular location: Plasma

RIGHT 0 conversion Fe2Tf BM FeBM 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeBM_0
stoichiometric coefficient: 2.0

GO:0005488
type: UnificationXref
id: GO:0005488
db: Gene Ontology

NTBI_0
type: PhysicalEntity
member physical entity: NTBI
cellular location: Plasma

RIGHT 0 conversion Rest NTBI NTBI STOICHIOMETRY
type: Stoichiometry
physical entity: NTBI
stoichiometric coefficient: 1.0

Fe2Tf
type: PhysicalEntity
member physical entity: Fe2Tf*
cellular location: Plasma

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

RIGHT 0 conversion Fe2Tf Liver FeLiver 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeLiver_0
stoichiometric coefficient: 2.0

LEFT 0 conversion Fe1Tf Liver Fe1Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe1Tf
stoichiometric coefficient: 1.0

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

RIGHT 0 conversion Fe1Tf Liver 0 FeLiver 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeLiver_0
stoichiometric coefficient: 1.0

Fe1Tf*_Fe2Tf*
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion Fe1Tf Fe2Tf Fe2Tf STOICHIOMETRY
participant stoichiometry: LEFT 1 conversion Fe1Tf Fe2Tf NTBI 0 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe1Tf Fe2Tf Fe1Tf STOICHIOMETRY
xref: GO:0005488
right: Fe2Tf
left: Fe1Tf
left: NTBI_0

FeDuo
type: PhysicalEntity
member physical entity: FeDuo*
cellular location: Duodenum

FeSpleen_0
type: PhysicalEntity
member physical entity: FeSpleen
cellular location: Spleen

RIGHT 0 conversion Fe2Tf Rest 0 FeRest STOICHIOMETRY
type: Stoichiometry
physical entity: FeRest
stoichiometric coefficient: 1.0

RIGHT 0 conversion Rest NTBI 0 NTBI 0 STOICHIOMETRY
type: Stoichiometry
physical entity: NTBI_0
stoichiometric coefficient: 1.0

Fe2Tf
type: PhysicalEntity
member physical entity: Fe2Tf*
cellular location: Plasma

FeLiver
type: SmallMolecule
xref: CHEBI:24875

FeBM_0
type: PhysicalEntity
member physical entity: FeBM*
cellular location: BoneMarrow

RIGHT 2 conversion Fe2Tf Rest 0 Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

FeSpleen
type: PhysicalEntity
member physical entity: FeSpleen*
cellular location: Spleen

HepcidinSynthesis
type: BiochemicalReaction
participant stoichiometry: RIGHT 0 conversion HepcidinSynthesis Hepcidin STOICHIOMETRY
xref: C61408
right: Hepcidin

LEFT 0 conversion Fe2Tf Rest 0 Fe2Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf
stoichiometric coefficient: 1.0

NTBI
type: PhysicalEntity
member physical entity: NTBI*
cellular location: Plasma

LEFT 0 conversion RestLoss FeRest STOICHIOMETRY
type: Stoichiometry
physical entity: FeRest
stoichiometric coefficient: 1.0

Hepcidin
type: PhysicalEntity
member physical entity: Hepcidin
cellular location: Plasma

Fe1Tf_0
type: PhysicalEntity
member physical entity: Fe1Tf
cellular location: Plasma

FeRest
type: PhysicalEntity
member physical entity: FeRest*
cellular location: RestOfBody

LEFT 0 conversion Fe2Tf Rest Fe2Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf_
stoichiometric coefficient: 1.0

LEFT 0 conversion Fe2Tf Liver Fe2Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf_
stoichiometric coefficient: 1.0

RIGHT 1 conversion Fe1Tf Duo Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

C75947
type: UnificationXref
id: C75947
db: NCIt

FeRest
type: PhysicalEntity
member physical entity: FeRest*
cellular location: RestOfBody

NTBI_0
type: PhysicalEntity
member physical entity: NTBI
cellular location: Plasma

Fe2Tf_Liver
type: Transport
participant stoichiometry: RIGHT 0 conversion Fe2Tf Liver FeLiver 0 STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe2Tf Liver Fe2Tf 0 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion Fe2Tf Liver Tf STOICHIOMETRY
xref: GO:0006826
right: Tf
right: FeLiver_0
left: Fe2Tf_0

FeSpleen_0
type: PhysicalEntity
member physical entity: FeSpleen
cellular location: Spleen

FeBM*
type: SmallMolecule
xref: CHEBI:24875

LEFT 0 conversion Duo NTBI 0 FeDuo 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeDuo_0
stoichiometric coefficient: 1.0

Liver_NTBI*
type: Transport
participant stoichiometry: LEFT 0 conversion Liver NTBI FeLiver STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Liver NTBI NTBI STOICHIOMETRY
xref: GO:0006826
right: NTBI
left: FeLiver

Hepcidin
type: Protein
xref: Q9EQ21

LEFT 0 conversion Duo NTBI FeDuo STOICHIOMETRY
type: Stoichiometry
physical entity: FeDuo
stoichiometric coefficient: 1.0

RIGHT 0 conversion Liver NTBI NTBI STOICHIOMETRY
type: Stoichiometry
physical entity: NTBI
stoichiometric coefficient: 1.0

LEFT 0 conversion Liver NTBI 0 FeLiver 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeLiver_0
stoichiometric coefficient: 1.0

NTBI
type: PhysicalEntity
member physical entity: NTBI*
cellular location: Plasma

RIGHT 0 conversion Fe1Tf Duo FeDuo STOICHIOMETRY
type: Stoichiometry
physical entity: FeDuo
stoichiometric coefficient: 1.0

RIGHT 0 conversion Liver NTBI 0 NTBI 0 STOICHIOMETRY
type: Stoichiometry
physical entity: NTBI_0
stoichiometric coefficient: 1.0

LEFT 0 conversion NTBI Fe1Tf 0 NTBI 0 STOICHIOMETRY
type: Stoichiometry
physical entity: NTBI_0
stoichiometric coefficient: 1.0

LEFT 0 conversion Spleen NTBI 0 FeSpleen 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeSpleen_0
stoichiometric coefficient: 1.0

RIGHT 0 conversion DuoLoss 0 FeOutside 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeOutside_0
stoichiometric coefficient: 1.0

LEFT 0 conversion DuoLoss 0 FeDuo 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeDuo_0
stoichiometric coefficient: 1.0

Fe1Tf_0
type: PhysicalEntity
member physical entity: Fe1Tf
cellular location: Plasma

Plasma
type: CellularLocationVocabulary
xref: BTO:0000131

RIGHT 1 conversion Fe1Tf Liver 0 Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

FeDuo_0
type: PhysicalEntity
member physical entity: FeDuo
cellular location: Duodenum

FeRest_0
type: PhysicalEntity
member physical entity: FeRest
cellular location: RestOfBody

RIGHT 0 conversion Fe1Tf Fe2Tf Fe2Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf_
stoichiometric coefficient: 1.0

RIGHT 0 conversion NTBI Fe1Tf 0 Fe1Tf 0 STOICHIOMETRY
type: Stoichiometry
physical entity: Fe1Tf_0
stoichiometric coefficient: 1.0

DuoLoss*
type: Transport
participant stoichiometry: LEFT 0 conversion DuoLoss FeDuo STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion DuoLoss FeOutside STOICHIOMETRY
xref: C25559
right: FeOutside
left: FeDuo

RIGHT 1 conversion Fe2Tf BM Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/28521769
type: PublicationXref
id: 28521769
db: PubMed

RIGHT 2 conversion Fe2Tf BM 0 Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

NTBI_0
type: PhysicalEntity
member physical entity: NTBI
cellular location: Plasma

Fe1Tf_0
type: PhysicalEntity
member physical entity: Fe1Tf
cellular location: Plasma

Liver_NTBI
type: Transport
participant stoichiometry: LEFT 0 conversion Liver NTBI 0 FeLiver 0 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Liver NTBI 0 NTBI 0 STOICHIOMETRY
xref: GO:0006826
right: NTBI_0
left: FeLiver_0

RIGHT 0 conversion Fe2Tf Rest FeRest 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeRest_0
stoichiometric coefficient: 2.0

FeDuo
type: SmallMolecule
xref: CHEBI:24875

Fe1Tf
type: Complex
xref: Q921I1
xref: CHEBI:29034

Fe2Tf_
type: PhysicalEntity
member physical entity: Fe2Tf**
cellular location: Plasma

FeBM_0
type: PhysicalEntity
member physical entity: FeBM*
cellular location: BoneMarrow

LEFT 1 conversion Fe1Tf Fe2Tf NTBI 0 STOICHIOMETRY
type: Stoichiometry
physical entity: NTBI_0
stoichiometric coefficient: 1.0

RIGHT 0 conversion RBC Spleen FeSpleen STOICHIOMETRY
type: Stoichiometry
physical entity: FeSpleen
stoichiometric coefficient: 1.0

RIGHT 0 conversion Fe2Tf BM 0 FeBM 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeBM_0
stoichiometric coefficient: 1.0

RIGHT 0 conversion Fe1Tf Fe2Tf 0 Fe2Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe2Tf
stoichiometric coefficient: 1.0

LEFT 0 conversion Fe1Tf Fe2Tf Fe1Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Fe1Tf
stoichiometric coefficient: 1.0

BioModels Database
type: Provenance
xref: BIOMD0000000735

Fe2Tf_
type: PhysicalEntity
member physical entity: Fe2Tf**
cellular location: Plasma

Fe2Tf_Rest
type: Transport
participant stoichiometry: RIGHT 0 conversion Fe2Tf Rest FeRest 0 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion Fe2Tf Rest Tf STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe2Tf Rest Fe2Tf 0 STOICHIOMETRY
xref: GO:0006826
right: FeRest_0
right: Tf
left: Fe2Tf_0

FeLiver
type: PhysicalEntity
member physical entity: FeLiver*
cellular location: Liver

RIGHT 1 conversion Fe1Tf Rest Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

NTBI
type: PhysicalEntity
member physical entity: NTBI*
cellular location: Plasma

FeBM_0
type: PhysicalEntity
member physical entity: FeBM*
cellular location: BoneMarrow

C61408
type: UnificationXref
id: C61408
db: NCIt

LEFT 0 conversion Liver NTBI FeLiver STOICHIOMETRY
type: Stoichiometry
physical entity: FeLiver
stoichiometric coefficient: 1.0

FeOutside_0
type: PhysicalEntity
member physical entity: FeOutside
cellular location: RestOfBody

FeRBC
type: PhysicalEntity
member physical entity: FeRBC*
cellular location: RBC

BM_Spleen*
type: Transport
participant stoichiometry: LEFT 0 conversion BM Spleen 0 FeBM 0 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion BM Spleen 0 FeSpleen STOICHIOMETRY
xref: GO:0006826
right: FeSpleen
left: FeBM_0

RIGHT 1 conversion Fe2Tf Liver 0 FeLiver 0 STOICHIOMETRY
type: Stoichiometry
physical entity: FeLiver_0
stoichiometric coefficient: 1.0

Fe1Tf
type: PhysicalEntity
member physical entity: Fe1Tf*
cellular location: Plasma

RIGHT 0 conversion DuoLoss FeOutside STOICHIOMETRY
type: Stoichiometry
physical entity: FeOutside
stoichiometric coefficient: 1.0

RIGHT 0 conversion Fe2Tf Liver FeLiver STOICHIOMETRY
type: Stoichiometry
physical entity: FeLiver
stoichiometric coefficient: 2.0

RIGHT 1 conversion Fe2Tf Liver Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

BioModels Database
type: Provenance
xref: MODEL1605030002

Tf
type: PhysicalEntity
member physical entity: Tf
cellular location: Plasma

Fe2Tf_0
type: PhysicalEntity
member physical entity: Fe2Tf
cellular location: Plasma

LEFT 0 conversion Spleen NTBI FeSpleen STOICHIOMETRY
type: Stoichiometry
physical entity: FeSpleen
stoichiometric coefficient: 1.0

RIGHT 2 conversion Fe2Tf Liver 0 Tf STOICHIOMETRY
type: Stoichiometry
physical entity: Tf
stoichiometric coefficient: 1.0

Fe2Tf_Liver*
type: Transport
participant stoichiometry: RIGHT 2 conversion Fe2Tf Liver 0 Tf STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe2Tf Liver 0 Fe2Tf STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion Fe2Tf Liver 0 FeLiver 0 STOICHIOMETRY
participant stoichiometry: RIGHT 0 conversion Fe2Tf Liver 0 FeLiver STOICHIOMETRY
xref: GO:0006826
right: FeLiver_0
right: FeLiver
right: Tf
left: Fe2Tf

Fe1Tf_0
type: PhysicalEntity
member physical entity: Fe1Tf
cellular location: Plasma

LEFT 1 conversion Fe1Tf Fe2Tf 0 NTBI STOICHIOMETRY
type: Stoichiometry
physical entity: NTBI
stoichiometric coefficient: 1.0

Fe2Tf_Rest*
type: Transport
participant stoichiometry: RIGHT 0 conversion Fe2Tf Rest 0 FeRest STOICHIOMETRY
participant stoichiometry: RIGHT 2 conversion Fe2Tf Rest 0 Tf STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe2Tf Rest 0 Fe2Tf STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion Fe2Tf Rest 0 FeRest 0 STOICHIOMETRY
xref: GO:0006826
right: FeRest_0
right: Tf
right: FeRest
left: Fe2Tf

BIOMD0000000735
type: UnificationXref
id: BIOMD0000000735
db: BioModels Database

Fe2Tf_Duo
type: Transport
participant stoichiometry: RIGHT 0 conversion Fe2Tf Duo FeDuo 0 STOICHIOMETRY
participant stoichiometry: RIGHT 1 conversion Fe2Tf Duo Tf STOICHIOMETRY
participant stoichiometry: LEFT 0 conversion Fe2Tf Duo Fe2Tf 0 STOICHIOMETRY
xref: GO:0006826
right: Tf
right: FeDuo_0
left: Fe2Tf_0

LEFT 0 conversion Fe1Tf Rest 0 Fe1Tf 0 STOICHIOMETRY
type: Stoichiometry
physical entity: Fe1Tf_0
stoichiometric coefficient: 1.0