Overview of Cat Genetic Testing For Neuromuscular Disorders
Describe the clinical course and diagnostic and genetic findings in a cat with X-linked myotubular myopathy. Case Summary A 7-month-old male Maine coon was evaluated for progressively worsening gait abnormalities and generalized weakness. Neurolocalization was to the neuromuscular system. Genetic testing for spinal muscular atrophy (LIX1) was ...
The information provided in this review will help veterinarians understand the genetic tests that should be requested, explains the best places to obtain genetic services and suggests recommendations for breed management based on test results. The practical tips - dos and don'ts - of genetic test usage in veterinary healthcare are also discussed.
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Learn about the veterinary topic of Congenital and Inherited Neuromuscular Disorders in Dogs and Cats . Find specific details on this topic and related topics from the Merck Vet Manual.
Neuromuscular disorders (NMDs) in cats represent a broad and complex spectrum of diseases that affect the motor unit, encompassing the peripheral nerves, neuromuscular junctions and skeletal muscles. Although relatively less common in feline patients compared to dogs, these disorders can have significant impacts on quality of life, and in some cases, may be progressive or even life-limiting ...
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Neuromuscular disorders in the cat
Feline neuromuscular diseases can be a diagnostic challenge. On initial inspection, the presenting signs can mimic disorders of other body systems, particularly cardiovascular, pulmonary and orthopaedic disease, or may be confused with systemic illnesses. Additionally, because many different pathologies of the feline neuromuscular system converge to a similar clinical phenotype, further ...
Comparative Neuromuscular Laboratory Genetics tests are available for some congenital myopathies, muscular dystrophies, peripheral neuropathies and congenital myasthenic syndromes for dogs and cats . The list of diseases and breeds for which genetic tests are available is growing and available at selected academic centers and commercial ...
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