VRTX Earnings Predictions — 2026-08-03

Ticker Report or Guide KPI Prediction Answer Confidence
VRTX Report Q2 2026 total revenue IN-LINE pred ~$3.25B vs. cons $3.23B MEDIUM
VRTX Report Q2 2026 non-GAAP EPS BEAT pred ~$4.93 vs. cons $4.85 MEDIUM
VRTX Report Q2 2026 JOURNAVX revenue MISS pred ~$51M vs. cons $55M MEDIUM
VRTX Guide FY2026 total revenue UNCHANGED guide ~$13.03B midpoint vs. cons $13.05B (FY2026) HIGH
VRTX Guide FY2026 non-CF product revenue LOWER guide ~$500M floor vs. cons $540M (FY2026) MEDIUM
VRTX Guide FY2026 non-GAAP R&D, acquired IPR&D and SG&A UNCHANGED guide ~$5.70B midpoint vs. cons $5.70B (FY2026) HIGH
VRTX Return Day-1 residual (stock − beta × S&P 500) -2.3% MEDIUM
VRTX Return 5-day cumulative residual -3.4% (FOLLOW-THROUGH) Predicted day-5 residual of -3.4% vs. day-1 residual of -2.3%: an EPS beat is likely to be outweighed by soft JOURNAVX monetization, a non-CF guide below the ~$540M consensus, demanding second-half revenue math, and Crinetics-related dilution that pressures out-period estimates. MEDIUM