VRTX Earnings Predictions — 2026-08-03

Ticker Report or Guide KPI Prediction Answer Confidence
VRTX Report Total revenue BEAT pred ~$3.27B vs. cons $3.23B MEDIUM
VRTX Report Non-GAAP diluted EPS BEAT pred ~$4.48 vs. cons $4.30 MEDIUM
VRTX Report Non-CF product revenue (CASGEVY + JOURNAVX) BEAT pred ~$0.120B vs. cons $0.110B LOW
VRTX Guide FY26 total revenue guidance UNCHANGED guide ~$13.03B midpoint vs. cons $12.97B (FY26) HIGH
VRTX Guide FY26 non-CF product revenue guidance UNCHANGED guide ~$0.50B minimum vs. cons $0.50B (FY26) MEDIUM
VRTX Guide Povetacicept IgAN regulatory timing UNCHANGED guide ~November 30, 2026 PDUFA vs. cons November 30, 2026 (2H26) HIGH
VRTX Return Day-1 residual (stock − beta × S&P 500) +2.8% MEDIUM
VRTX Return 5-day cumulative residual +1.0% (FADE) The initial ~+2.8% residual reaction to a modest revenue/EPS and non-CF-sales beat should fade toward ~+1.0% over five days because reiterated ~$0.50B FY26 non-CF guidance still requires an approximately ~$0.154B average quarterly non-CF run-rate in 3Q–4Q after an estimated ~$0.120B 2Q result, leaving out-period revenue and EPS estimates vulnerable to modest cuts. MEDIUM