PFE Earnings Predictions — 2026-08-04

Ticker Report or Guide KPI Prediction Answer Confidence
PFE Report Adjusted EPS BEAT pred ~$0.70 vs. cons $0.68 MEDIUM
PFE Report Total Revenue MISS pred ~$14.2B vs. cons $14.4B MEDIUM
PFE Report COVID franchise revenue (Comirnaty + Paxlovid) MISS pred ~$0.9B vs. cons $1.1B LOW
PFE Guide FY2026 Revenue Guidance UNCHANGED guide ~$59.5-62.5B (midpoint $61.0B) vs. cons $61.0B (FY2026) HIGH
PFE Guide FY2026 Adjusted EPS Guidance LOWER guide ~$2.80-3.00 (midpoint $2.90) vs. cons $2.96 (FY2026) MEDIUM
PFE Guide Cumulative LOE revenue impact through 2028 (post-Vyndamax settlement) BETTER guide ~$14.5B vs. prior guide ~$17B (2026-2028 cumulative) MEDIUM
PFE Return Day-1 residual (stock − beta × S&P 500) -1.5% MEDIUM
PFE Return 5-day cumulative residual -2.5% (FOLLOW-THROUGH) An EPS beat is likely low-quality (cost controls/below-the-line) against a soft COVID-driven revenue miss, while FY26 guidance is only reaffirmed (not raised) for a third straight quarter, forcing sell-side to trim H2 COVID and top-line assumptions even after the headline beat. With no fresh catalyst to counter the SigVie-002 oncology overhang, HSBC-style caution, and a lame-duck CFO on the call, negative revisions to out-period numbers likely compound the initial reaction rather than reverse it, pulling the stock lower over the following days before dividend yield/valuation support limits further downside. MEDIUM