Insulin treatment is essential for individuals with type 1 diabetes because the hallmark of type 1 diabetes is absent or near-absent β-cell function. Inadditiontohyperglycemia, insulinopenia can contribute to other metabolic disturbances like hypertriglyceridemia and ketoacidosis as well as tissue catabolism that can be life threatening.
1 Background Glycaemiccontrolis a treatment pillar for reducing the risk of both micro- and macrovascular complications in type 2 diabetes mellitus (T2DM) [1] , and early and intensive glycaemiccontrolhas a legacy effect in reducing cardiovascular and kidney disease events and all-cause mortality even after 24 years [2] .
This cross-sectional study examines associations of the frequency of continuous glucose monitoring withglycemiccontrolamong people with type 2 diabetes.
Self-care practices enable the maintenance of optimalglycemiccontrolfor patients with diabetes through a comprehensive lifestyle, medication adherence, and monitoring of blood glucose levels, preventing the complications of diabetes.
Theadditionof fotagliptin to metformin treatment shows enhanced and clinically meaningfulglycemiccontrolinpatients with type 2 diabetes who show inadequatecontrolwith metformin alone.
This particular example perfectly highlights why In Addition To Glycemic Control is so captivating.
Glycemictargets are generally set somewhat higher for older adults and for those with comorbidities or a limited life expectancy and little likelihood of benefit from intensive therapy. (See'Glycemicmanagement' above and "Glycemicmanagement and vascular complications in type 2 diabetes mellitus", section on 'Choosing aglycemictarget'.)
