A Structure Based Virtual Screening Identifies A Novel Mdm2 Antagonist

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This study used our newly designed structure-based virtual screening approach on a commercial compound library to identify a novel compound, CGMA-Q18, which directly binds to MDM2 , leading to the ...

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A Structure Based Virtual Screening Identifies A Novel Mdm2 Antagonist

Download Citation | On Oct 9, 2024, Qing-yong Hu and others published A structure-based virtual screening identifies a novel MDM2 antagonist in the activation of the p53 signaling and inhibition ...

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A Structure Based Virtual Screening Identifies A Novel Mdm2 Antagonist

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This study used our newly designed structure-based virtual screening approach on a commercial compound library to identify a novel compound, CGMA-Q18, which directly binds to MDM2 , leading to the activation of p53, the induction of apoptosis, and cell cycle arrest in cancer cells.

Article " A structure-based virtual screening identifies a novel MDM2 antagonist in the activation of the p53 signaling and inhibition of tumor growth" Detailed information of the J-GLOBAL is an information service managed by the Japan Science and Technology Agency (hereinafter referred to as "JST"). It provides free access to secondary information on researchers, articles, patents, etc., in ...

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Protein Structure Virtual Lab at Cody Learmonth blog. It gives the article a little more context before the image collection begins.

(PDF) Identification of new inhibitors of Mdm2-p53 interaction via. This note connects the source idea with the visuals in a simple, reader-friendly way.

Full article: Searching for novel MDM2/MDMX dual inhibitors through a. This note connects the source idea with the visuals in a simple, reader-friendly way.

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