Overview of Evaluating Glp-1 Agonist Therapy For Seniors
Effect of glucagon-like peptide-1 receptor agonist therapy on cardiorenal outcomes in patients aged ≥ 80 years with Type 2 diabetes.
Background Type 2 diabetes mellitus is highly prevalent among older adults and often requires multidrug therapy to optimize glycemic control while minimizing adverse effects. Glucagon-like peptide-1 receptor agonists ( GLP-1 RAs) are among the most effective antihyperglycemic drugs with demonstrated cardiometabolic benefits. However, their real-world safety, tolerability, and long-term outcomes ...
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GLP1 Receptor Agonist Therapy and Cardiorenal Outcomes in Patients ...
Background Glucagon‐like peptide‐1 receptor agonists ( GLP‐1 RAs) have demonstrated potential in improving glycemic control and reducing adverse outcomes in patients with Type 2 diabetes mellitus (T2DM); however, their efficacy in individuals aged 80 years and older remains understudied. To evaluate the efficacy of GLP‐1 RAs compared with dipeptidyl peptidase‐4 inhibitors (DPP4i) in ...
What does this review add? GLP - 1 RA therapy appears to be safe and effective for managing obesity in older adults, with compa-rable weight loss and glycemic control to younger individuals. Serious adverse events seem similar, but older adults may experience higher rates of constipation and hypoglycemia.
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