Overview of Glp 1 Programs The Neurovascular Landscape Cell Metabolism
Chen et al. summarize the recent literature on GLP -1R signaling in the different systems of the neuro-glial-vascular unit. This work provides novel insights into GLP -1R agonism, transcending its known role in weight loss and blood glucose control.
GLP-1 programs the neurovascular landscape Bandy Chen Xiaofei Yu Claudia Horvath-Diano María José Ortuño Matthias H. Tschöp Ania M. Jastreboff Marc Schneeberger Cell Metabolism Vol. 36 No. 10 pp. 2173-2189 · Elsevier BV View at Publisher Save 10.1016/j.cmet.2024.09.003
Key Details About Glp 1 Programs The Neurovascular Landscape Cell Metabolism
GLP-1 programs the neurovascular landscape October 2024 Cell Metabolism 36 (10):2173-2189 DOI: 10.1016/j.cmet.2024.09.003 Authors: Bandy Chen
GLP-1 programs the neurovascular landscape Bandy Chen, Xiaofei Yu, Claudia Horvath-Diano, María José Ortuño, ... Marc Schneeberger
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In exploring the intricate connection between obesity and neurological conditions, recent literature suggests that GLP -1R ag-onism may have the capacity to shape the neurovascular landscape . Thus, GLP -1R agonism emerges as a promising strategy for addressing the complex interplay between metabolic health and cognitive well-being.
In exploring the intricate connection between obesity and neurological conditions, recent literature suggests that GLP -1R agonism may have the capacity to shape the neurovascular landscape . Thus, GLP -1R agonism emerges as a promising strategy for addressing the complex interplay between metabolic health and cognitive well-being.
Overview of Glp 1 Programs The Neurovascular Landscape Cell Metabolism
Whether GLP -1R agonism directly impacts brain health or does so indirectly through improved metabolic health remains to be elucidated. In exploring the intricate connection between obesity and neurological conditions, recent literature suggests that GLP -1R agonism may have the capacity to shape the neurovascular landscape .
Substantial evidence suggests that GLP-1 RAs not only enhance insulin secretion and improve glycemic control but also exert protective effects on the CNS, primarily through their neurovascular benefits [ 14 ].
Key Details About Glp 1 Programs The Neurovascular Landscape Cell Metabolism
Notably, these processes overlap with pathways modulated by GLP-1 signaling across systemic and central compartments. GLP-1 receptors are expressed in neurons, glial cells , and components of the neurovascular unit, providing a biological basis for possible neurological effects.
Whether GLP -1R agonism directly impacts brain health or does so indirectly through improved metabolic health remains to be elucidated. In exploring the intricate connection between obesity and neurological conditions, recent literature suggests that GLP -1R agonism may have the capacity to shape the neurovascular landscape .