Oral weight loss medications
There is one MHRA-approved, over-the-counter oral weight loss medication available in the UK. It's a drug called 'orlistat' that's sold under the brand name Alli. Orlistat has gone through rigorous clinical trials and has been found to be safe and effective when taken according to directions.
The safety of weight loss pills can vary based on whether they are prescription medications or over-the-counter supplements. Prescription weight loss pills have undergone rigorous testing and are generally considered safe when used under medical supervision.

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Top 8 Best Over the Counter Weight Loss Supplements in 2026

Over the counter weight loss supplements may interact with other medications , so it is important to consult with a healthcare professional before taking any supplements.
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