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T-complex protein 1-ring complex (TRiC)/chaperonin containing T-complex protein 1 (CCT) subunit enhances retrograde axonal transport by modulating tau phosphorylation . CCT enhances retrograde axonal transport of brain-derived neurotrophic factor (BDNF) in primary cortical neurons. The net effect on retrograde axonal transport of BDNF by CCT is the reduction in pauses with a concomitant ...

Tcomplex protein 1ring complex enhances retrograde axonal transport ...

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Expression of a single TRiC subunit increased the level of ptau while downregulation of the TRiC complex decreased ptau. We further demonstrated that TRiC-mediated increase in ptau induced detachment of tau from microtubules. Our study has thus revealed that TRiC-mediated increase in tau phosphorylation impacts retrograde axonal transport.

T-complex protein 1-ring complex (TRiC)/chaperonin containing T-complex protein 1 (CCT) subunit enhances retrograde axonal transport by modulating tau phosphorylation .CCT enhances retrograde axonal transport of brain-derived neurotrophic factor (BDNF) in primary cortical neurons. The net effect on retrograde axonal transport of BDNF by CCT is the reduction in pauses with a concomitant increase ...

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(PDF) T

PDF | On Aug 17, 2018, Xu-Qiao Chen and others published T-complex protein 1-ring complex enhances retrograde axonal transport by modulating tau phosphorylation | Find, read and cite all the ...

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Visual Reference: A Fyn Localises To The Postsynapse In A Tau Dependent

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