GI Lymphoma in Cats
Learn about GI lymphoma in cats , including the common signs, causes, and treatment options to help manage this serious condition.
Feline High-Grade Gastrointestinal (GI) Lymphoma What is a feline high-grade GI lymphoma ? In general, lymphoma is a cancer of a type of white blood cell called a lymphocyte. High-grade GI lymphoma specifically is an aggressive form of cancer in cats , which is often wide spread at diagnosis.
Feline GI lymphoma
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June 16, 2026 — Gastrointestinal lymphoma is now one of the most common cancers in cats , and a new Foundation-funded study is using cutting-edge gene mapping technology to improve diagnosis and open the door to better treatment options.
Lymphoma is a cancer of the lymphocytes. Lymphocytes are cells that are involved in the immune system. Lymphoma is connected with feline leukemia, a viral infection. Feline lymphoma most commonly affects the intestines. Therefore, clinical signs of lymphoma are often similar to other intestinal diseases. Diagnosing lymphoma requires finding cancerous cells on microscopic examination. Lymphoma ...
The symptoms, diagnosis, and treatment of lymphoma in cats
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Find out what you need to know about lymphoma in cats (feline lymphoma ). Learn about the symptoms, diagnosis, staging, and treatment of this condition.
Small cell lymphoma is a slow-growing, cancer-causing gut thickening, whilst large cell lymphoma creates hard tumours in your cat's guts and/or stomach. Large cell lymphoma in cats is far more aggressive and has a poorer prognosis.
Addressing gastrointestinal lymphomas in felines
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Results from a 2022 study found 78% of 860 submitted feline intestinal biopsy specimens confirmed evidence of lymphosarcoma (LSA), with most cases of the disease occurring in the small intestine and stomach. 1 Using these data, Steven Suter, VMD, PhD, MS, DACVIM (Oncology), explained the prevalence of LSA in cats during a lecture at the North American Veterinary Community's 2023 Veterinary ...
The most common form of LSA in cats is alimentary or gastrointestinal (GI) lymphoma and it accounts for 50-70% of all feline LSA cases. It is most common in senior with an average age at diagnosis of 9 to 13 years. Mediastinal lymphoma affects lymphoid organs (thymus or lymph nodes) in the chest and is more often seen in younger cats with an average age at onset of 5 years. This type of LSA is ...
Feline lymphoma is a malignant cancer of the lymphatic system, the exquisitely structured arrangement of internal organs and tissues that directly or indirectly influences virtually every aspect of a cat's physical existence. Unfortunately, says Margaret McEntee, DVM, professor of oncology at Cornell University's College of Veterinary Medicine, it is the most frequently diagnosed among all ...
"Small cell GI lymphoma is the most common cancer of a cat's digestive system and a highly prevalent feline cancer overall," Hayburn said. "It can form anywhere along the digestive tract, including the stomach, small intestine, or colon."
