Intrahepatic cholestasis of pregnancy (ICP) occurs mainly in the third trimester and is characterised by pruritus and elevated serum bile acid levels. ICP is associated with an increased perinatal risk and higher rates of foetal morbidity and mortality.
Intrahepatic cholestasis of pregnancy commonly presents in the second and third trimester with unexplained pruritus sine materia, abnormal liver function tests, and/or elevated serum total bile acid concentration.
Intrahepatic cholestasis of pregnancy with marked elevation of transaminases in a black American.Intrahepatic cholestasis of pregnancy and its complications. Analysis of 100 cases in Chongqing area. Chin Med J.1986; 99 : 957-960.
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SUMMARY Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disease that occurs during pregnancy. Typically, patients with ICP present with pruritus and an elevation in transaminases and serum bile acid concentration.
Intrahepatic cholestasis of pregnancy usually becomes apparent in the third trimester of pregnancy. Bile flow returns to normal after delivery of the baby, and the signs and symptoms of the condition disappear.
Routine Viral and Autoimmune Tests in Intrahepatic Cholestasis of Pregnancy: Are They Really Necessary?Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific liver condition marked by impaired bile flow that occurs in the later stages of pregnancy.
Current guidelines recommend viral, autoimmune, coagulation and liver ultrasound testing in intrahepatic cholestasis of pregnancy to exclude alternative diagnoses.
