In this video Justin Groce talks about the diabetes weight loss medication Exenatide (Byetta, Bydureon), and how it can be used in a health optimization prot...
Exenatide therapy results in weight loss, with mean changes of -1.3 to -8.0 kg across clinical trials.In fasted, diabetic Rhesus monkeys exenatide reduced 4000 plasma glucose concentrations with an ED50 of 0.25 g/kg 0.09 log in (Figure 2F).
Based on published literature describing weight loss with exenatide treatment among individuals with type 2 diabetes, we hypothesized that responders would stratify into a plateau group and a continued weight loss group by 52 weeks of treatment.
of more weight gain; exenatide failed to achieve a decrease in fasting plasma glucose but had the.Similarly to the aforementioned studies, exenatide also caused significant weight loss. (difference -4.6 kg), but similar HbA1c compared to glargine (-0.8 versus -0.7, respectively) [24].
Factors regarding exenatide-related weight loss have been underrecognized.Conclusion Exenatide provides more weight loss in the patients with higher baseline BMI or fT4. Thyroid function remains unchanged during treatment.
Weight loss with exenatide was 1.5 3.1 kg.Long-term effects of exenatide therapy over 82 weeks on glycemic control and weight in over-weight metformin treated patients with type 2 diabetes mellitus. Diabetes Obes Metab. 2006;8:419-428.
