Theobromine And Dog Mitophagy Related Function

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Comparative theobromine metabolism in five mammalian species.

Biotransformation of theobromine (TBR) was compared in rats, mice, hamsters, rabbits, and dogs by assaying urinary metabolites using HPLC after oral administration of a 5 mg/kg dose containing 8-14C-TBR. Recovery of radioactivity ranged from 60-89% of the dose in urine, and from 2-38% of the dose in feces, with most material being excreted during the first 48 hr after dosing. TBR was most ...

Theobromine poisoning is commonly caused by chocolate ingestion, where a dog finds a household item containing chocolate (O'Brien, 1998). Pet dogs in families that celebrate Christmas and Easter are especially susceptible to theobromine toxicosis due to increased amounts of chocolate commonly being consumed by people during both of these ...

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Effects of short

Exretion patterns of TBR and its metabolites were qualitatively similar among species, indicating that TBR is metabolized along similar pathways. Biotransformation of theobromine (TBR) was compared in rats, mice, hamsters, rabbits, and dogs by assaying urinary metabolites using HPLC after oral administration of a 5 mg/kg dose containing 8-14C-TBR. Recovery of radioactivity ranged from 60-89% ...

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Possible chocolate poisoning in a dog

The lethal dose of theobromine for dogs is 100-500 mg / kg, at a low dose may appear mild signs (agitation and vomiting), at higher doses can be observed cardio-toxic effects and cause death in ...

Additional Notes on Theobromine And Dog Mitophagy Related Function

Mechanisms of Mitophagy in mammals. Some OMM proteins, such as BNIP3. It gives the article a little more context before the image collection begins.

Frontiers | Targeting cellular mitophagy as a strategy for human cancers. It gives the article a little more context before the image collection begins.

Frontiers | Mechanisms and Functions of Mitophagy and Potential Roles. This note connects the source idea with the visuals in a simple, reader-friendly way.

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