Melatonin Overdose Data and Statistics: A Widening Concern
According to the American Association of Poison Control Centers' National Poison Data System (NPDS), the annual number of pediatric melatonin ingestions has increased by 530% between 2012 and 2021, with a total of 260,435 ingestions reported. This represents a significant public health concern, particularly among young children, who are often more susceptible to melatonin overdose.

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Several factors contribute to the increasing use of melatonin supplements among children and adolescents, including:

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Consequences of Melatonin Overdose

The consequences of melatonin overdose can be severe, particularly among young children. According to recent studies, nearly 15% of children who ingested melatonin supplements required hospital care, and two children died as a result of melatonin overdose. Furthermore, the increased use of melatonin supplements has led to a significant rise in emergency department visits for unintentional melatonin ingestions among infants and young children.
Despite the growing concerns surrounding melatonin use among children and adolescents, there is a lack of long-term safety data for melatonin supplements in this population. To address this gap, further research is needed to investigate the effects of melatonin use on bone growth and sexual maturation in children and adolescents.
2. American Association of Poison Control Centers. (2022). National Poison Data System (NPDS). National Poison Data System, 2012-2021.