Luxury Hotel Downtown St. Louis

An Urban Oasis in Downtown St . Louis Experience Four Seasons Hotel St . Louis , a luxury hotel set along the banks of the Mississippi River in the heart of downtown . Just steps from the Gateway Arch, Busch Stadium and the city's best dining and entertainment, our urban retreat offers the ideal blend of sophistication and comfort.

Offering an experience like few other hotels in the area, The Ritz-Carlton, St . Louis is a luxury hotel tucked within the Arts and Garden District of Clayton, Missouri. Step onto the balcony of your luxury hotel room or suite and catch a glimpse of the downtown St . Louis skyline, enjoy a taste of the Sorrento Coast in Casa Don Alfonso or unwind from the day with a massage or a workout in our ...
Hotel Saint Louis, Autograph Collection

Book a distinctive stay at Hotel Saint Louis , Autograph Collection. Premium accommodations, unique rooms & great service await you.
Experience luxury at The Truitt, a boutique hotel in Downtown St . Louis , MO. Enjoy elegantly designed rooms, world-class amenities, and a prime location in the heart of St . Louis . Book your stay directly and get the best rates. Perfect for both leisure and business travelers visiting St . Louis .

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
A St . Louis Original Since 1925 Discover the Charm of Magnolia Hotel St . Louis Step into a storied stay at Magnolia Hotel St . Louis , a Tribute Portfolio Hotel , where historic character meets modern allure in the heart of downtown . Originally opened in 1925 as the iconic Mayfair Hotel , this architectural gem has welcomed guests for a century and built a legacy of thoughtful firsts.
If you're searching for the best luxury hotel , there are 26 deals in Saint Louis Downtown St . Louis district. One of the best highly-rated hotels is St . Louis Union Station Hotel , Curio Collection By Hilton (rating: 8.0/10), set a 10-minute walk from The Pepper Lounge.

THE 10 BEST Saint Louis Luxury Hotels
Best Luxury Hotels in Saint Louis on Tripadvisor: Find traveler reviews, candid photos, and prices for 11 luxury hotels in Saint Louis , Missouri, United States.
Book the Best Downtown Saint Louis Hotels on Tripadvisor: Find 36,750 traveler reviews and 12,852 candid photos, and prices for 25 hotels in Downtown .

The 20 best Luxury Hotels in Saint Louis. Complete Guide 2026
MAY 2026. The best luxury hotels in Saint Louis , USA. Modern and unique four star hotels , boutique hotels or five star hotels with personal service, indoor pools and great restaurants.








Five Star Alliance: the best luxury hotels in St Louis , MO. Great rates, stunning photos and easy, secure booking. Discover the luxury hotel experts.