Funding: Approximately $5.6M to fund two awards, with a total cost cap of $2.8M per award.
Doc Type: BAA
Clearance:No
Program Manager: N/A
Last Updated: 2026-08-19 14:52
Analyzed File:HT942526MRPFPARM_GG2.pdf
Eligibility Reasoning
Extramural and intramural U.S. Department of War (DOW) organizations are eligible to apply... Applications from investigators within the DOW and applications involving multidisciplinary collaborations among academia, industry, DOW, U.S. Department of Veterans Affairs (VA) and other federal government agencies are highly encouraged.
Note: This is an AI-generated summary...
Summary
The Fiscal Year 2026 (FY26) Melanoma Research Program (MRP) Focused Program Award – Rare Melanomas (FPA-RM) is a grant supporting a multidisciplinary research program focused on a single, overarching question relevant to rare melanomas. The program must consist of two to three distinct but complementary research projects. It requires a collaborative team structure with one Initiating Principal Investigator (PI) and one or two Partnering PIs, with each PI leading one project. A key feature is the mandatory inclusion of at least one rare melanoma survivor or patient advocate on the research team. The award allows for projects across the entire research spectrum, including clinical trials. The total combined funding for the entire program is capped at $2.8 million for a maximum performance period of four years. Submission is a two-step process requiring a pre-application, and only invited applicants may submit a full application.
Overall Technical Areas
Rare Melanoma ResearchMelanoma Prevention and InterceptionTumor Dormancy and MetastasisCancer Biology and EtiologyGenetic and Molecular SubtypingHistologic Cancer AnalysisClinical Trial DesignPreclinical Animal ModelsCancer Diagnosis and DetectionBiomarker Discovery and ValidationHuman Biospecimen AnalysisBiostatistical Data AnalysisTreatment Outcome ResearchQuality of Life Studies
Probable LBNL Areas
N/A
Focus Areas
Example Priorities:
Applications for the FPA-RM may propose projects across the entire research spectrum (biology, etiology, prevention, diagnosis and detection, prognosis, treatment and quality of life) and must address a critical unmet need relevant to rare melanomas.
The MRP is particularly interested in receiving applications that address other uncommon presentations of melanoma, including but not limited to: Genetic (molecular subtypes).
Uncommon presentations of melanoma, including but not limited to: ... Histologic (desmoplastic and acral lentiginous).
Uncommon presentations of melanoma, including but not limited to: ... Tissue of origin (mucosal, acral).
The MRP seeks to fund research that will lead to improved detection and monitoring capabilities (particularly for individuals at highest risk) as well as inhibition of melanoma initiation, early dissemination, emergence from tumor dormancy and metastases (i.e., interception).
Applications for the FPA-RM may propose projects across the entire research spectrum (...prevention, diagnosis and detection, prognosis...).
Applications for the FPA-RM may propose projects across the entire research spectrum (...treatment...).
A research project proposing a clinical trial must include preliminary data.
The MRP acknowledges that domestic dogs can spontaneously develop mucosal melanoma. FY26 applications proposing mucosal melanoma studies involving pets that are voluntarily enrolled in studies at the owner’s discretion may be considered...
Melanoma survivorship research covers a broad range of research areas that have the goal of improving the health and well-being of melanoma survivors and their families/care partners.
The MRP seeks to fund innovative and impactful research that advances studies in preservation of function (physical ability), quality of life improvement, symptom management, treatment outcomes, and support for psychological and social issues...
Applicants to the FPA-RM must collaborate with the rare melanoma consumer community to maximize the impact and translatability of the research for the benefit of the intended community(ies).
Specific Technical Skills:
Quality of Life AssessmentPsycho-OncologyHealth Services ResearchSymptom ManagementPatient-Reported OutcomesCommunity-Based Participatory ResearchPatient AdvocacyHealth Disparities ResearchLong-term Follow-up Care
Potential PIs for this Area:
Name
Score
Organization
Potential LBNL PIs (Overall)
Note on PI Matching: These suggestions are generated through an AI-driven semantic analysis of LBNL staff profiles.
BSA | Biological Systems & Engineering | Department of BioEngineering and BioMedical Sciences · Preclinical Animal Models
Fundamental Research Exemption (FRE)
In accordance with National Security Presidential Memorandum-33 and all associated laws, all fundamental research funded by the DOW must be evaluated for affiliations with foreign entities.
ONHS Funding Opportunity Report