ONHS Report: HT942526OCRPIIRA

DoW, Ovarian Cancer, Investigator-Initiated Research Award

Solicitation ID: HT942526OCRPIIRA

Agency: DHA

Type: Grant

Deadline: 2026-10-01T00:00:00 ET

Eligibility: Yes (Unrestricted)

Funding: Total program funding is approximately $16.45M for about 14 awards. Individual awards have a total cost cap of $1.05M for a single PI or a combined total cost cap of $1.40M for Partnering PIs.

Doc Type: BAA

Clearance: No

Program Manager: help@eBRAP.org

Last Updated: 2026-08-19 15:03

Analyzed File: HT942526OCRPIIRA_GG.pdf

Eligibility Reasoning

Extramural and intramural U.S. Department of War (DOW) organizations are eligible to apply, including foreign and domestic organizations, for-profit and nonprofit organizations, and public or private entities... applications involving multidisciplinary collaborations among academia, industry, the DOW, the U.S. Department of Veterans Affairs (VA) and other federal government agencies are highly encouraged.

Note: This is an AI-generated summary...

Summary

The Department of War's Ovarian Cancer Research Program (OCRP) is soliciting applications for the Investigator-Initiated Research Award (IIRA) to fund high-impact research addressing critical needs in ovarian cancer. The award supports projects from basic laboratory to translational research, but explicitly excludes clinical trials. With approximately $16.45 million available to fund around 14 awards, applicants can request up to $1.05 million for a single Principal Investigator (PI) project or a combined total of $1.40 million for a Partnering PI option, both for a maximum performance period of four years. Eligibility requires PIs to be at or above the Assistant Professor level. Applications must include preliminary data and address at least one of the program's Areas of Emphasis, such as developing novel therapies, improving diagnostics, enhancing survivorship, or investigating links between military service exposure and ovarian cancer. Submission is a two-step process, with pre-applications due July 13, 2026, and invited full applications due October 1, 2026.

Overall Technical Areas

Novel Therapeutic StrategiesCancer Risk StratificationEarly Cancer DetectionDiagnostic and Prognostic MethodsSurvivorship & Quality of Life ResearchMilitary Exposure-Cancer LinksOvarian Cancer PreventionBasic Cancer BiologyCancer Etiology and InitiationCancer Progression and MetastasisCancer Recurrence BiologyOvarian Cancer GeneticsTranslational ResearchRigorous Experimental DesignStatistical Analysis & Planning

Probable LBNL Areas

N/A

Focus Areas

Example Priorities:

Understand the basic biology and etiology of ovarian cancer initiation, progression, metastasis, recurrence, genetics and other critical events.
Investigate innovative approaches for ovarian cancer prevention.

Specific Technical Skills:

Molecular BiologyCancer GeneticsCell BiologyTumor MicroenvironmentMetastasis ResearchEpigeneticsPathologyPreclinical ModelingTranslational Research

Potential PIs for this Area:

Name	Score	Organization

Example Priorities:

Identify and develop new strategies for risk stratification, screening, early-stage detection, accurate diagnosis and prognosis.

Specific Technical Skills:

Biomarker DiscoveryGenomicsProteomicsDiagnostic Assay DevelopmentMedical ImagingBioinformaticsEpidemiologyBiostatisticsEarly Detection Technologies

Potential PIs for this Area:

Name	Score	Organization

Example Priorities:

Develop novel therapeutic strategies for treatment.

Specific Technical Skills:

Drug DiscoveryPharmacologyImmunotherapyTargeted TherapyMedicinal ChemistryHigh-Throughput ScreeningPreclinical ModelsToxicologyTranslational Oncology

Potential PIs for this Area:

Name	Score	Organization

Example Priorities:

Identify and implement strategies to improve care, survivorship and quality of life.

Specific Technical Skills:

Health Services ResearchPatient-Reported OutcomesSurvivorship ScienceQuality of Life AssessmentPsychosocial OncologyPalliative CareImplementation ScienceClinical Research

Potential PIs for this Area:

Name	Score	Organization

Example Priorities:

Identify relationships between military service-related exposures and ovarian cancer.
Explain how the proposed research will have an impact on the health and well-being of Service Members, Veterans and their Family Members.

Specific Technical Skills:

EpidemiologyToxicologyEnvironmental HealthExposure ScienceMilitary HealthPopulation HealthBiostatisticsDatabase AnalysisVeteran Health Research

Potential PIs for this Area:

Name	Score	Organization

Potential LBNL PIs (Overall)

Note on PI Matching: These suggestions are generated through an AI-driven semantic analysis of LBNL staff profiles.

Name	Score	Organization
James Garbe	0.74	BSA \| Biological Systems & Engineering \| Department of BioEngineering and BioMedical Sciences · Cancer Etiology and Initiation
Jennifer Rosenbluth	0.74	· Basic Cancer Biology
Jian-Hua Mao	0.74	BSA \| Biological Systems & Engineering \| Department of BioEngineering and BioMedical Sciences · Early Cancer Detection
Yuan Mei	0.72	PSA \| PHY \| Atlas · Rigorous Experimental Design
Ling Jin	0.72	ETA \| Energy Analysis \| Systems & Energy Tech Analysis · Statistical Analysis & Planning
Gerard Marriott	0.72	BSA \| Molecular Biophysics & Integrated Bioimaging \| Cellular & Tissue Image · Novel Therapeutic Strategies
Zixi Hu	0.72	CSA \| AMCR \| Mathematics · Statistical Analysis & Planning
Satyarth Praveen	0.71	CSA \| SciData \| Data Science Applications · Diagnostic and Prognostic Methods
Michelle O'Malley	0.71	BSA \| Biological Systems & Engineering \| Biodesign Dept · Rigorous Experimental Design
Amy Kronenberg	0.71	BSA \| Biological Systems & Engineering \| Biodesign Dept · Military Exposure-Cancer Links

Fundamental Research Exemption (FRE)

In accordance with National Security Presidential Memorandum-33 and all associated laws, all fundamental research funded by the DOW must be evaluated for affiliations with foreign entities.